20/07/2025
Your allergy medication?
One of the most commonly used and readily available medication for allergies is diphenhydramine, more commonly known under the trade name - Benadryl! But is there really a space for it in the current context of newer options available.
A recent article appearing on the World Allergy Organization Journal under the title - Diphenhydramine: It is time to say a final goodbye - indicates that "presence of effective and safer second-generation antihistamines, frequent and sometimes severe adverse reactions to first-generation agents, [and] its demonstrated abuse potential."
In clinical practice, there are many options now available that have much less side effects, the newer antihistaimines (anti-allergy) are also more targeted and selective in terms of their mechanisms of action. As it is, diphenhydramine can affect almost any organ and while most persons are not aware, it shouldn't be used in persons who have dry eyes, peptic ulcer disease, those who are constipated or have urinary retention and should be used with caution in those who are older than 65 or those having any form of dementia.
Of course, there is no clinical indication as a 'sleep medication' or 'sleep aid' as this is commonly used and abused in Belize!
Talk to your doctor about the better options for diphenhydramine (Benadryl).