10/15/2025
Do you ever feel like your brain is not your brain anymore? 🤯
The exact words I said to my colleague about two years ago were “I feel like I’m going crazy.” And yes, I was peri-menopausal. And yes, here's why I felt that way 👇👇👇 as described by Deanna Minich PhD:
"A review in Brain Sciences highlights how estrogen receptors shape women’s mental health and cognition during the menopausal transition. Estrogen influences neurotransmitters, synaptic connections, and neuroplasticity in regions tied to memory, mood, and learning. This aligns with Dr. Lisa Mosconi’s brain imaging research showing profound midlife changes as estrogen declines.
The message is clear: women’s brain health must be central to the menopause conversation. Menopause is not only an endocrine shift. It is a whole-body and whole-brain transition."
Reference/image credit: Cho JM, Lee J, Ahn EM, Bae J. Beyond Hot Flashes: The Role of Estrogen Receptors in Menopausal Mental Health and Cognitive Decline. Brain Sci. 2025 Sep 16;15(9):1003. doi: 10.3390/brainsci15091003. PMID: 41008363.