
10/09/2025
Melatonin is a hormone naturally produced by the brain’s pineal gland. It plays a key role in regulating your circadian rhythm, or sleep-wake cycle. As daylight fades, melatonin levels rise, signaling to your body that it’s time to wind down. Melatonin supplements mimic this effect and are commonly used to help with insomnia, jet lag, and delayed sleep phase disorder. They’re especially helpful for shift workers or anyone adjusting to a new sleep schedule.
So, are melatonin supplements safe? For most adults, short-term use is considered safe and non-addictive. However, side effects can occur, including headache, dizziness, nausea, daytime drowsiness, and vivid dreams or nightmares. Less common effects include mood changes, stomach cramps, and reduced alertness. Melatonin may also interact with medications for blood pressure, diabetes, seizures, and birth control.
That’s why it’s important to speak with a healthcare provider before starting melatonin—especially if you’re taking other medications or have underlying health conditions.