12/18/2025
Every nutrient and herb is going to be slightly different in terms of possible interactions.
The reality, however, is that most nutrients are fine to combine together and most things are quite flexible in terms of how you take them. Herbs have a little bit more potential for interactions with medications (more on that next week!). You should always check with your healthcare provider!
If you’re taking a medication that’s meant to be taken away from anything else (like synthroid), you should also take it away from supplements, but many medications and nutrients can be taken at the same time.
For most nutrients and medications, it's much more important that you can take them consistently than that you worry about the time when you're taking them.
Iron is a classically cited example where we know that calcium can slightly decrease absorption as can dairy products, coffee, tea, and grains; and acidic foods may support absorption. These things are definitely true in terms of dietary iron intake, but in a supplement form you’re still going to get a lot of iron from the product if you’re taking a good dose even if you’re taking it at ‘the wrong time’. For most people finding a time that you can consistently take will be more important than avoiding the things that slightly decrease absorption.
If it’s easy enough to remember, we might consider taking it at dinner time or at bedtime as those are times that are easier to avoid those interactions, but if you’re not going to remember to take it except for with breakfast, I actually just want you to take it!
Most nutrients can be taken at the same time, iron and calcium are the only ones that we might try to separate if possible. And most things don't inherently matter if they're paired with or without food.
Food matters less for absorption typically, and more as a way to decrease the risk of digestive side effects in someone who is sensitive digestively. Most people will find that they need to take zinc and iron with food as they can hurt your stomach on an empty stomach.
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