02/20/2026
GROUND-BREAKING STUDY: A simple digital treatment involving gameplay has been shown to dramatically reduce intrusive trauma memories within one month.
Six months on, some participants were symptom-free.
The research, involving Oxford experts, also found significant reductions in overall PTSD symptoms.
The study, funded by Wellcome Trust, carried out a randomised controlled trial of 99 healthcare workers exposed to trauma at work during the Covid-19 pandemic. The results demonstrate huge potential to implement a highly scalable, low intensity, easily accessible digital treatment that could transform how we prevent and treat PTSD for people who have been exposed to trauma worldwide.
According to the World Health Organization, psychological trauma – exposure to severe injury, death, or sexual violence – affects seven out of 10 of people at least once in their lifetime. Severe trauma can lead to PTSD, experienced by millions of people globally, and often presents as sudden, unwanted intrusive memories accompanied by very distressing emotions.
Existing therapies for PTSD are effective yet remain widely inaccessible. They tend to be resource-intensive – requiring multiple sessions with specialists – are widely unavailable, and are not recommended for those facing ongoing trauma.
The new study tested an intervention developed at Uppsala University in collaboration with P1vital, and trialled with collaborators including the University of Cambridge, and Oxford University. The focus was on treating intrusive, vivid, and unwanted memories of trauma, a hallmark symptom of PTSD.
After recalling a memory, participants learned how to use a cognitive skill called mental rotation, which involves rotating 2D and 3D shapes using your ‘mind’s eye’. They then used this skill to play a slower form of the video game Tetris, which similarly involves rotating geometric blocks. This is thought to occupy the brain’s visuospatial areas, competing with the visual flashback, weakening its vividness and emotional impact – and critically, the frequency with which it intrudes.
To actively compare against this treatment, one control group of the trial listened to music by Mozart, reputed for therapeutic benefits to alleviate stress, and informational podcasts about him. In a second control group, participants received only standard care.
After just one month, researchers found a stark reduction in intrusive memories, commonly known as flashbacks, for those using the Tetris-based treatment – ten times fewer than either control group. It remained highly effective after six months, with 70% of participants who received it reporting no intrusive memories at all, even alleviating other PTSD symptoms.