05/15/2025
The brain directly influences the gut microbiome. And a new study shows it can change gut bacteria in just 2 hours.
In a surprising twist to the gut-brain connection, scientists have now shown that the brain can change the gut microbiome—and fast.
A new study in mice found that brain signals could alter the composition of gut bacteria within just two hours. This adds strong support to the idea that communication between the gut and brain is bidirectional, not just microbes affecting mood and cognition, but brain activity shaping the microbial ecosystem as well.
While researchers have long known that gut microbes can influence brain function and mental health, this study is one of the first to demonstrate that the brain can send rapid signals that reshape the microbiome.
The discovery could have major implications for understanding how stress, emotions, or neurological conditions might directly impact gut health. It also opens the door to new therapeutic strategies that target brain pathways to influence digestion, immunity, and overall wellness.
learn more about the gut and brain: https://scopeblog.stanford.edu/2025/03/06/gut-brain-connection-long-covid-anxiety-parkinsons/
