This is what EDS looks like

04/08/2026

Is your GP unsure how to support you to manage your hypermobility?

This happens a LOT. So much so that we created a one-page Quick Reference Guide for GPs who need a bit of help in that area. The document is freely available on our website, downloadable, printable and links to our Clinician's Guide, which gives even more detailed information about the kind of issues someone with symptomatic hypermobility might face.

More info and all the links here: https://www.hypermobility.org/post/a-quick-reference-guide-a-year-on

04/08/2026

Now available to download and print are wallet cards for each type of Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorder (HSD).

The wallet cards are available in US and UK printing sizes. One side features the EDS or HSD type, and on the reverse is a scannable QR code that links to the type-specific webpage featuring signs and symptoms of that type and further information.

Click here to download your wallet card today: https://www.ehlers-danlos.com/download-your-wallet-card/

02/28/2026

Mast cell activation doesn’t begin in the immune system; it starts in the mitochondria. Under persistent environmental or physiological stress, from toxins, EMFs, infections, or trauma, mitochondria shift into defense mode: ATP production drops, oxidative stress rises, and mitochondrial contents (ATP, mtDNA) leak extracellularly.

Mast cells respond with a cascade of over 1,200 inflammatory mediators, including peroxynitrite – a molecule that damages mitochondrial membranes and DNA, deepening the immune activation. This is a closed-loop system of self-amplifying cellular distress.

I expand on this topic in my newsletter. Comment MCAS to receive it.

Disclaimer: The information shared in this post is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional for specific medical guidance and treatment.

11/05/2025

The Glitch

The Glitch is inspired by my individual personal story of dealing with chronic illnesses, specifically "Pots" or Postural Orthostatic Tachycardia Syndrome. a...

10/28/2025

10/22/2025

Kids with complex, invisible illness and their families face unimaginable hurdles as they confront failing medical and child protective systems.

10/22/2025

The Ehlers-Danlos Society is delighted to welcome you to register for the EDS ECHO Summit: Mental Health, a virtual event held on November 1, 2025. This event is suitable for community members, their friends, families, and caregivers, as well as healthcare professionals.

10/21/2025

Emerging research shows that Ehlers-Danlos Syndromes (EDS) involve more than collagen defects. Dysregulation of the immune system—especially mast cells and complement—may increase tissue injury and affect healing in pEDS and hEDS/HSD.

➡ Understanding these connections is key to developing personalized treatments for neurological and spinal symptoms in EDS.

🔗Learn more about the connection between EDS & Chiari: https://youtu.be/QEmNDyzJa-g

Dr. Anne Maitland is an Associate Professor in the Department of Medicine, Division of Rheumatology and Director of the Ehlers Danlos Syndrome Institute at the Medical University of South Carolina (MUSC).