04/15/2025
🧠 Estrogen + Your Brain in Perimenopause & Menopause
Estrogen plays a major role in brain health — and during perimenopause and menopause, as levels begin to fluctuate and decline, the brain can really feel the shift.
Here’s how it can show up;
1️⃣ Mood changes
Estrogen supports the production of key neurotransmitters like serotonin and dopamine. When estrogen drops, mood changes like anxiety, irritability, or low mood can become more noticeable.
2️⃣ Brain fog + forgetfulness
Estrogen enhances memory, learning, and verbal recall. Without that support, you might find it harder to concentrate or feel mentally “foggy.”
3️⃣ Sleep issues + hot flashes
Estrogen helps regulate your internal thermostat and circadian rhythms. This is why sleep disturbances, night sweats, or temperature swings often increase during this transition.
4️⃣ Stress sensitivity
Estrogen helps regulate the HPA axis (your stress response system). Lower levels can leave you feeling more overwhelmed or reactive to stress.
5️⃣ Neuroprotection
Estrogen supports blood flow, reduces inflammation, and promotes neuron health — offering long-term benefits for cognitive function.
✨ The takeaway: If you’re feeling off, forgetful, or just not yourself — you’re not alone, and you’re not imagining it.
These shifts are real. And there’s support available to help you feel clearer, calmer, and more like you again.