04/16/2021
Gastrointestinal Adverse Effects of Immunotherapeutic Agents: A Systematic Review
By Dushyant Singh Dahiya, Farah Wanib, Jean Claude Guidic, Asim Kichlooa
Department of Internal Medicine, Central Michigan University, Saginaw, MI, USA
Department of Family Medicine, Samaritan Medical Center, Watertown, NY, USA
Department of Internal Medicine, Samaritan Medical Center, Watertown, NY, USA
Corresponding Author: Dushyant Singh Dahiya, Central Michigan University College of Medicine, 1000 Houghton Avenue, Saginaw, MI 48602, USA
"In 1909, Smith first speculated that the immune system could supress the growth of carcinomas by recognizing tumor cells as foreign antigens [1]. Hence, the immune system became an area of particular interest to investigators due to its specificity in targeting tumor-specific antigens. Immunotherapy is primarily focused on the development of agents to stimulate or supress the immune system as needed to fight off a wide spectrum of diseases, particularly cancer. Progress in the field is largely based on the identification of new immune based targets and a better understanding of the workings of the immune system [2]. Although still in its infancy stage, cancer immunotherapy (CI) is rapidly evolving and advancing to a point that it is considered a separate therapeutic entity and a potential fifth pillar in the management of cancers alongside surgical intervention, chemotherapy, radiotherapy and targeted therapy"
See full article at https://www.gastrores.org/index.php/Gastrores/article/view/1340/1340
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Gastrointestinal Adverse Effects of Immunotherapeutic Agents: A Systematic Review