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The Weight Loss Lab, 1801B Ottawa, ON, Canada, Ontario K1A 0K9, Toronto, ON (2025)

08/06/2025

Highlights from
At , our attendees were fully engaged in a series of dynamic and engaging sessions! 🙌
From cutting-edge treatments to the latest research advances, the enthusiasm and active participation was truly inspiring. It was a celebration of knowledge sharing and collaboration!

08/06/2025

Our laboratory capacity
Highly qualified staff:
Scientists and researchers: they have advanced academic training and extensive experience in research.
Technical staff: Competent in laboratory techniques and the use of specialized equipment.
Administrative and support staff: Ensure the daily running of the laboratory.
Advanced equipment and techniques:
High precision instruments: including microscopes, centrifuges, PCR machines and flow cytometers.
Advanced technology: Such as gene sequencers, mass spectrometers and high-performance screening systems.
Robust IT infrastructure: Powerful computing resources for storing, processing and analyzing data.
Strict safety and hygiene standards:
Biosafety: Implementation of biosafety facilities, sterile work areas and appropriate waste management procedures.
Chemical safety: Safe handling and storage of chemicals.
Staff safety: Use of personal protective equipment (PPE), regular safety training and first aid resources available on site.

08/06/2025

💖 Mood and weight: the power of your emotional world 💖
Hello everyone, I'm Dr. Sophia Turner.
Today I want to talk about an often overlooked but very important factor for weight management: the link between mood and weight.

😔 How does your mood affect your weight?
🍫 Eating for emotions
When we feel stressed, anxious or depressed, we often turn to food to comfort our emotions, especially snacks that are rich in sugar and fat. This can easily lead to an excessive calorie intake.
🔄 Hormonal changes
Negative emotions can alter hormonal balance. For example, they can raise levels of ghrelin (the hunger hormone) while lowering leptin (the satiety hormone), making us feel hungrier than usual.
Slower metabolism
Chronic stress and negative emotions can slow down the metabolism, making it easier to store fat in the body.
😴 Poor sleep quality
Poor mood often affects sleep, and lack of sleep further disrupts hormone regulation, creating a vicious cycle.

🌈 How do you improve your mood to support weight management?
🧘‍♀️ Practice emotional regulation
Take a few minutes each day to meditate or breathe deeply. These simple techniques can help calm your mind and relieve emotional tension.
👫 Stay socially engaged
Talk to friends or family. Sharing your feelings and seeking emotional support can make a big difference.
🏃‍♀️ Exercise regularly
Physical activity not only burns calories, but also improves mood and reduces stress levels in a natural way.
💤 Make good sleep a priority
Adequate rest is crucial for emotional balance and metabolic health. Aim to sleep between 7 and 9 restorative hours each night.

Improving your mood will not only make you feel better, but it also plays a key role in supporting sustainable weight management.
Remember, health is not just about a number on the scale, but also about your overall quality of life and inner well-being.

08/06/2025

The hidden dangers of excessive fat accumulation
Excess fat, especially the visceral fat surrounding the internal organs, is not just an aesthetic problem. It significantly increases the risk of chronic diseases. Here we explain how fat accumulation affects health in general:
🫀 Cardiovascular risks

Hypertension: Abdominal obesity increases blood pressure and is a major risk factor for heart disease and stroke.

Coronary artery disease: Visceral fat favors atherosclerosis (hardening and narrowing of the arteries), which increases the likelihood of heart attacks and other cardiovascular events.

🍬 Blood sugar and diabetes

Type 2 diabetes: Abdominal obesity causes insulin resistance, which makes blood sugar regulation more difficult and increases the risk of type 2 diabetes.

🩸 Cholesterol and liver health

High cholesterol: Excess fat can increase LDL ('bad cholesterol') levels, contributing to plaque build-up and cardiovascular complications.

Non-alcoholic fatty liver disease (NAFLD): Visceral fat is a key factor in the accumulation of fat in the liver, which can lead to inflammation, fibrosis, cirrhosis or liver failure.

😴 Sleep problems and breathing difficulties

Sleep apnea: Fat deposits in the throat and upper airways increase the risk of obstructive sleep apnea, a condition characterized by interrupted breathing during sleep, which is linked to fatigue, cognitive problems and heart disease.

🦴 Joint pain and mobility problems

Osteoarthritis: Being overweight puts strain on the knees, hips and lower back, accelerating wear and tear on joints and increasing the risk of osteoarthritis.

🧴 Ageing and skin elasticity

Loss of collagen and elasticity: Obesity can change the structure of the skin, causing wrinkles, sagging and premature ageing.

🎗 Increased cancer risk

Obesity is associated with a higher risk of cancer, such as breast cancer, colorectal cancer and uterine cancer. Adipose tissue affects hormonal levels, which can influence tumor growth.

🫛 Gallstones and digestive problems

Gallstones: High levels of cholesterol and fat increase the risk of gallstone formation, which can cause serious digestive problems that require medical treatment.

🧠 Mental health and hormonal imbalances

Depression and anxiety: Obesity is often linked to low self-esteem, emotional stress and increased risk of mood disorders.

Hormonal imbalance: Visceral fat can increase levels of cortisol (stress hormone) and estrogen, affecting metabolism, immune system and reproductive health.

🔹 Important to consider:
✅ Visceral fat is a major cause of heart disease, diabetes and metabolic disorders.
✅ It also contributes to sleep problems, joint pain, skin ageing and mental health.

08/06/2025

Lymphatic obstruction is a common health problem that can lead to the accumulation of toxins in the body, triggering a range of negative effects. One of the main consequences is body fat accumulation and fluid retention. When lymphatic flow is disrupted, toxins are not effectively removed from the tissues, affecting cell function, slowing down metabolism and increasing the risk of weight gain and edema.

08/06/2025

Lymphoedema is a condition characterized by the accumulation of lymphatic fluid in local tissues, causing swelling due to a disruption in lymphatic drainage. It can affect any part of the body, but usually affects the arms, legs or face. The etiology is usually classified into two broad categories: primary lymphedema and secondary lymphedema.

Primary lymphedema:
Primary lymphedema is usually caused by congenital malformations of the lymphatic system and often has an inherited component. Possible causes include:

Genetic anomalies: some people are born with underdeveloped lymphatic vessels, leading to disturbed drainage. This type of lymphedema can occur at birth or during childhood.

Disticiasis lymphedema syndrome: Rare genetic disorder characterized by the presence of two rows of eyelashes (disticiasis) linked to lymphedema.

Secondary lymphedema (acquired):
Secondary lymphedema is the result of external factors that block normal lymph flow. Common causes are:

Surgery: Cancer treatments may require the removal of lymph nodes or lymphatic vessels, which can interfere with lymphatic drainage and cause swelling. This is often the case in the treatment of breast cancer, prostate cancer or uterine cancer.

Radiation therapy: Radiation therapy can damage or scar lymph nodes and lymph vessels, disrupting lymph circulation and causing lymphedema.

Infections: Severe infections such as schistosomiasis or filariasis can cause inflammation or damage to the lymph nodes, disrupting lymphatic function.

Trauma or post-surgical complications: Injuries such as burns or surgical incisions can damage lymphatic vessels and cause localized swelling.

Chronic diseases: Conditions such as heart failure, liver cirrhosis or kidney disease can cause generalized fluid retention, which can trigger or worsen lymphedema.

Obesity: Severe obesity increases the risk of lymphedema because excess fat tissue can compress lymphatic vessels and impede circulation.

Inflammatory and autoimmune diseases: Chronic inflammatory conditions such as rheumatoid arthritis and systemic lupus erythematosus can affect lymphatic circulation and increase the risk of edema.

08/06/2025

Do you want to learn more about the molecular mechanisms, diagnosis and treatment of diabetes? You can now apply for the postgraduate program in diabetes.

08/06/2025

🩸 In type 2 diabetes, the body's ability to release insulin is affected, leading to elevated blood sugar levels.
💡 A study by Efraim Westholm and Lena Eliasson at the Diabetes Center at Harvard Medical School shows how levels of the protein IGFBP7 are elevated in the islets of Langerhans in people with type 2 diabetes.

The Weight Loss Lab

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