04/08/2026
The most common type of bladder cancer is urothelial carcinoma. “This arises in a specialized cell layer on the inner surface of the urinary tract,” explains Ramkishen Narayanan, M.D., a urologist.
“The urothelium has the unique property of having multiple cell layers that can transition from stretched to contracted as the bladder fills and empties, which is why bladder cancer is also known as transitional cell carcinoma.”
The number-one sign that should prompt a call to your doctor is called “gross painless hematuria,” or blood in the urine that is not associated with pain. “This may involve a brief episode of bloody urine that stops and then returns several days or weeks later. Inflammatory and infectious conditions such as a kidney stone or urinary tract infection typically involve pain or burning with urination.. Bladder tumors, on the other hand, typically do not cause pain at first.
Constant need to p*e or urinating more often in the absence of a urinary tract infection also merits further investigation, especially if you have a family history or a history of smoking. Anything that feels out of the ordinary is worth making an appointment.
When the initial cancer is caught before spreading, the survival rate for bladder cancer is 98%.