12/17/2024
Congratulations to researchers from John Hopkins University and Johns Hopkins All Children's Hospital for their remarkable research on pulmonary hypertension (PAH) and its metabolic effects. The John Hopkins team utilized our to filter and prepare the tissue samples before conducting ๐๐-๐ ๐ฆ ๐ฎ๐ป๐ฎ๐น๐๐๐ถ๐, enabling precise sample handling through solid-phase extraction. Read about VERSA here: https://www.aurorabiomed.com/product/automated-liquid-handling/
Their method involved treating rodent models to mimic human PAH symptoms. Through this approach, they were able to extract tissue samples and analyze metabolic changes associated with the diseaseโs progression. Notably, they observed changes in tissue metabolite levels in addition to physical changes such as ventricular sizes.
Interested in learning more? Check out the white paper/publication below:
White paper:https://www.aurorabiomed.com/wp-content/uploads/2024/07/Aurora-Whitepaper-VERSA110-VersaMetabolicProfiing.pdf
Publication:https://www.aurorabiomed.com/wp-content/uploads/2024/07/2023-VERSA1100-SPE-LLE-Simpson-Spatial-and-temporal-resolution-of-metabolic-dysregulation-in-the-Sugen-hypoxia-model.pdf
Authors: Catherine E. Simon, Anjira S. Ambade,Robert Harlan MS,Aurelie ROUX, David Graham, Neal Klauer, Tijana Tuhy, Todd Kolb, Karthik Suresh, Paul Hassoun, Rachel Damico
Automated Liquid Handling System for Genomics including Next Generation Sequencing, NGS Library Preparation, Microarray spotting, and more.