
03/05/2023
Here’s something interesting!…. several studies have demonstrated beneficial associations between the circadian clock and drug responses in patients with cancer. Using chemotherapy in this way is called chronotherapy (“chrono” meaning time and “therapy” meaning treatment)
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In this study adult patients with a type of lymphoma called diffuse large B cell lymphoma (DLBCL) received their chemo and targeted therapy either in the morning (one group of patients) or afternoon (another group).
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Interestingly, survival and side effects were significantly WORSE for FEMALE, but not male patients, if treatment was received in the MORNING.
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The authors conclusion was “In female DLBCL patients, R-CHOP treatment in the AFTERNOON can reduce toxicity while it improves efficacy and survival outcome.
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👩⚕️I hope to see chronotherapy emerge with more research as part of standard of care, while oncologic care becomes moreand more personalized🙌 We must treat the whole person!!!
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