Centre for Molecular Medicine and Therapeutics

Centre for Molecular Medicine and Therapeutics RESEARCHING LIFE to CHANGE LIVES

It is with great pleasure that we announce the appointment of Dr. Bruce Verchere as the Director of the Centre for Molec...
07/22/2019

It is with great pleasure that we announce the appointment of Dr. Bruce Verchere as the Director of the Centre for Molecular Medicine and Therapeutics (CMMT).

Dr. Verchere is a highly accomplished researcher and Professor in the Departments of Pathology and Laboratory Medicine and Surgery. He is a prominent member of both the UBC and BC Children's Hospital Research Institute (BCCHR) communities.

Over the course of its twenty-year history, CMMT researchers have made significant achievements advancing the state of health research and making changes to the lives of children and families in BC and beyond. As a Faculty of Medicine Senate-approved centre, CMMT currently supports ten principal investigators dedicated to understanding the genetic, epigenetic and environmental factors that contribute to disease and translating this specialized knowledge into new prevention, diagnosis and treatment strategies. As a scientist and academic of international standing and an experienced administrator with a long track record of success, Dr. Verchere is uniquely well suited to build on this exceptional legacy and advance CMMT's vital mission.

As head of the Canucks for Kids Fund (CFKF) Diabetes Research Laboratories since its creation in 2002, Dr. Verchere has established BC Children's as a national leader in the field of pediatric diabetes research. During his time in this role he has built a multi-disciplinary team of over 100 world-class researchers, trainees and staff, secured several major infrastructure grants, and developed an engaged provincial network to further research into understanding the causes of type 1 and type 2 diabetes and improving treatments. Throughout this time, Bruce has continued to pursue his own leading-edge research on the functioning of insulin-producing beta cells and how their dysfunction or failure contributes to type 1 and type 2 diabetes.

A well-respected leader, Dr. Verchere has offered tireless service to BC Children's and UBC, as well as the larger research community in Canada. He is currently a member of BCCHR's Research Leadership Council and the Faculty of Medicine Faculty Academic Reappointment, Promotion, and Tenure Committee. He has also served on the national boards of Diabetes Canada and Partners in Research and on the CIHR Institute of Nutrition, Metabolism, and Diabetes Institute Advisory Board.

In the coming weeks, BCCHR will begin recruitment for a new head of the Canucks for Kids Fund Diabetes Research Laboratories. Dr. Verchere will continue in this role until a successor is identified.

On behalf of CMMT, BC Children's Hospital Research Institute and the UBC Faculty of Medicine, please join us in congratulating Dr. Verchere on this appointment.

03/26/2019

The SBN Biotech Expo is a major annual event that showcases the best and the brightest of the BC Biotech and Life Sciences industry

03/26/2019

The latest volume of Human Gene Therapy features the research findings published by the joint effort of the Simpson and Wasserman labs at Centre for Molecular Medicine and Therapeutics.

Figure caption: In vivo fundus autofluorescence (FAF) demonstrated intense expression (white) in the perifoveal ring, optic nerve, and nerve fibers.

The Simpson and Wasserman labs used computational biology and mined the human genome for the best genes from which to de...
03/20/2019

The Simpson and Wasserman labs used computational biology and mined the human genome for the best genes from which to develop a novel minimal promoter element(s) designed for expression in restricted cell types (MiniPromoter) to improve the safety and efficacy of retinal ganglion cell gene therapy.

To read more about their latest exciting findings:
https://www.liebertpub.com/doi/10.1089/hum.2018.118

Centre for Molecular Medicine and Therapeutics

Human Gene TherapyVol. 30, No. 3Research ArticlesOpen AccessOpen Access licenseNew MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina Elizabeth M. Simpson, Andrea J. Korecki, Oriol Fornes, Trevor J. McGill, Jorge Luis Cueva-Vargas,....

01/31/2019
Recently published in FASEB journal, the Hayden Lab identified a novel caspase protease site that regulates mutant HTT a...
11/27/2018

Recently published in FASEB journal, the Hayden Lab identified a novel caspase protease site that regulates mutant HTT aggregation, indicating caspase-1 might be target to promote mutant HTT clearance in Huntington disease.

ResearchIdentification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearanceDale D. O. Martin, Mandi E. Schmidt, Yen T. Nguyen, Nikola Lazic, and Michael R. HaydenDale D. O. MartinDepartment of Medical Genetics, Centre for Molecular Medicine and Therapeutics, The....

11/13/2018

A layer of tissue that’s only a single cell thick is all that that separates our intestines from the world of microbes living inside our gut. Until recently, scientists believed this layer, which is called the intestinal epithelium, was just a simple protective barrier. Thanks to work done in Dr. ...

11/09/2018

New Times Higher Education global subject rankings have been released, with UBC at 26 in Life Sciences, 52 in Physical Sciences, 12 in Psychology and 30 in Pre-clinical, Clinical & Health. http://ow.ly/as9R30mxqid

The Department of Medical Genetics is holding their annual Research Day at Life Sciences Institute tomorrow (Nov 9th), p...
11/08/2018

The Department of Medical Genetics is holding their annual Research Day at Life Sciences Institute tomorrow (Nov 9th), please see poster below for detail:
University of British Columbia
UBC Faculty of Medicine

11/08/2018

The Allen Institute in Seattle announced today their 2018 Next Generation Leaders, a group of six early-career neuroscientists who will participate in a special advisory council for the Allen Institute for Brain Science, a division of the Allen Institute.

10/30/2018

How do vaccines work at a population level? How can Canadians address health inequities beyond our own borders? Check out the video of Dr. Julie Bettinger's and Dr. Gina Ogilvie's presentations from last week's Mini Med School to learn about these topics and more:bit.ly/2OZb1DW

10/30/2018

This year our Department of Medicine Research Expo will be held at the Paetzold Health Education Centre, Vancouver General Hospital on November 7, 2018.

10/24/2018

seminar this Wednesday at 12 pm at LSC3; Dr. Elizabeth M. Simpson from Centre for Molecular Medicine and Therapeutics: "CRISPR for Gene Therapy and Novel Mouse Models"

10/22/2018

An enterovirus could be the cause, but proof is elusive

10/12/2018

Join us! Our Research Services team is looking for a full-time Administrative Coordinator. Check out this great opportunity: bit.ly/2yu3q5y

We are looking forward to hosting Prof. Surani and Dr. Murray during the Gairdner symposium on Oct 22.Gairdner Foundatio...
10/04/2018

We are looking forward to hosting Prof. Surani and Dr. Murray during the Gairdner symposium on Oct 22.

Gairdner Foundation
University of British Columbia

2018 Gairdner International Symposium Time: 3:30- 6:00 pm, Monday, October 22, 2018 Venue: LSC2, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6…

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