International Journal of Particle Therapy

08/01/2026

Adenoid cystic carcinoma of the head and neck is a rare malignancy with a high risk of perineural invasion, local recurrence, and distant metastasis and poses unique challenges due to its aggressive nature, resection limited by morbidity, and prior radiation.

Proton therapy, with its ability to spare normal tissues via the Bragg peak, may offer a promising and safe re-irradiation approach, especially in patients not amenable to resection requiring high definitive doses.

Read a study in press now with IJPT that evaluates outcomes of patients with recurrent adenoid cystic carcinoma treated with proton radiation: https://www.sciencedirect.com/science/article/pii/S233151802500561X

01/01/2026

Classical Hodgkin lymphoma is associated with favorable prognosis and high overall survival. Consolidative proton therapy represents a modality recommended for young patients due to its reduction in exit dose, with a goal to minimize late effects.

Start off the New Year with an important study presenting outcomes of pediatric patients with classical Hodgkin lymphoma receiving consolidative proton therapy: https://www.sciencedirect.com/science/article/pii/S2331518025005608

15/12/2025

15/12/2025

Only 1 month left to submit your abstract for !

Share your research & innovations in particle therapy before 13 Jan 2026!!

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PTCOG 64 – Join us from 8-13 June 2026 in Deauville, Normandy, France. Discover the latest research, innovations, and clinical advancements in particle therapy.

11/12/2025

IJPT Vol.18 is now online!

Read about advances in proton & carbon-ion therapy across clinical, technical and biological fronts: improved target coverage for pancreatic cancer, proton reirradiation for lung, RBE practice, automated QA/planning, treatment-time benchmarks, and radiobiology insights - https://www.sciencedirect.com/journal/international-journal-of-particle-therapy/vol/18/suppl/C

21/11/2025

Rates of local regional recurrence and secondary metachronous thoracic tumors remain high for patients with inoperable early and locally advanced non-small cell lung cancer treated with prior radiation.

These clinical situations pose therapeutic challenges due to the potential added toxicity of reirradiation.

During Lung Cancer Awareness Month, we are pleased to present a study demonstrating the feasibility and efficacy of a hypofractionated course of proton reirradiation for recurrent thoracic tumors - in press with IJPT now: https://www.sciencedirect.com/science/article/pii/S2331518025004780

14/11/2025

Developing consensus guidelines and integrating advanced relative biological effectiveness (RBE) and LET-based models into treatment planning could improve precision and safety of proton therapy.

Read the results of an important survey of 29 U.S. proton therapy centers assessing awareness and management of RBE variability in clinical practice: https://www.sciencedirect.com/science/article/pii/S2331518025004779

12/11/2025

Our first AI in Particle Therapy Special Issue article is available!

Radiotherapy can lead to radiation-induced optic neuropathy, with vision loss and visual field deficits related to damage to the optic pathways: Accurately quantifying visual field deficits and establishing their spatial relationship with anatomical structures and radiation dose distribution remains a significant challenge.

Learn how researchers from Université de Caen- Normandie; Centre François Baclesse; and Hôpital de La Croix-Rousse, Hospices Civils de Lyon applied a novel artificial intelligence approach in oncology to identify patterns of visual field loss and model their spatial evolution over time after pencil beam scanning proton therapy: https://www.sciencedirect.com/special-issue/10J8TL0GQ4D

27/10/2025

Kidney cancer represents 4% of all new cancer cases in the United States and there has been a consistent increase in its incidence over recent decades, largely attributed to more frequent use of routine imaging studies for unrelated medical reasons.

Read a study in press now with IJPT that suggests proton-based SBRT improved target coverage while reducing the dose to OARs in primary renal cell carcinoma patients: https://www.sciencedirect.com/science/article/pii/S2331518025004755

06/10/2025

The modern proton therapy center is a complex environment – numerous factors influence patient treatment time – and with 29 new centers opened last 5 years, the National Association of Proton Therapy reports that the number of patients treated with protons has nearly tripled since 2012.

There is a pressing need for data from modern proton therapy centers to inform operational planning for new facilities and provide benchmarks for existing ones: Read important treatment time insights from the Baptist Health Miami Cancer Institute’s Real Time Location Service (RTLS) system, in press with IJPT now - https://www.sciencedirect.com/science/article/pii/S2331518025004731

03/10/2025

Most automatic error detection studies in radiation therapy focus on photon therapy, with limited attention to proton therapy. Read a UF Health Proton Therapy study that developed and validated an automated framework for initial proton therapy plan review, enhancing error detection capabilities and workflow efficiency in pencil beam scanning (PBS) treatments - learn more: https://www.sciencedirect.com/science/article/pii/S233151802500472X