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Geistlich Ortho

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Wolhusen
Geistlich Ortho

Geistlich is specialised in biomaterials for the regeneration of bone and cartilage.

02/10/2025

🚨 Exciting Clinical Milestone

🦵 OrthoPure®XT from Tissue Regenix Group is a safe, off-the-shelf product in ACL Reconstruction!

The first-in-human 5-year clinical study of a novel porcine xenograft for ACL reconstruction has just been published in the Journal of Experimental Orthopaedics.

✅ Key Highlights:
- 40 patients treated with a decellularized porcine tendon graft
- No immunogenic response observed
- Clinical outcomes comparable to autografts and allografts
- Graft ruptures limited to young male patients
- MRI and radiographic results support safety and performance

This study marks a significant step forward in expanding graft options for ACL surgery, offering a biomechanically sound and immunologically safe alternative.

📄 Read the full publication in our bio!

Contact us for more information ➡️ gpag.ortho@geistlich.ch

29/09/2025

Cartilage Image of the month – September 2025 🍁🍂

🖼️ Selected as the Cartilage Image of the Month September, this case was submitted by Dr. Andrejs Finogejevs (LV).
A 42-year-old active female office worker presented with pain, stiffness, and limited knee motion for two months (VAS 4–6). Conservative treatment included NSAIDs and a knee brace. Imaging revealed a 1.5 x 2.5 cm cartilage defect on the medial femoral condyle.

Dr. Finogejevs performed a mini-open chondroplasty and microfracture. At 6 months post-op, the patient reported no pain, had returned to sports activities, and was fully weight-bearing without crutches.

At 6 months post-op, the patient was pain-free, active in sports, and walking without crutches. The one-year follow-up image shows a well-filled defect, with cartilage regeneration reaching the level of the surrounding tissue—indicating a successful outcome and excellent tissue remodeling.

25/06/2025

Mark your calendars! 📅

On 1 July, the 𝗔𝗚𝗔𝗻𝘆𝘄𝗵𝗲𝗿𝗲 𝗥𝗼𝗮𝗱𝟮𝗛𝗮𝗺𝗯𝘂𝗿𝗴 kicks off with “Move on: Patellaluxation” – an interactive online event by Winglet Community 🦵

We’re proud to support this exciting stop on the road to the AGA Congress in Hamburg!

🎟 Free registration & full details via

30/05/2025

Selected as the Cartilage Image of the Month May, this case was submitted by Dominik Wilkens (🇩🇪).

👤 𝗣𝗮𝘁𝗶𝗲𝗻𝘁 𝗣𝗿𝗼𝗳𝗶𝗹𝗲: 38-year-old female patient presented with an extensive retropatellar cartilage defect measuring approximately 6 cm².

👉 𝗦𝘂𝗿𝗴𝗶𝗰𝗮𝗹 𝗔𝗽𝗽𝗿𝗼𝗮𝗰𝗵: The defect was treated using a 30x40 mm collagen membrane, tailored to fit the lesion. To optimize patellar tracking and reduce lateral pressure, the procedure was complemented by a Z-plasty lengthening of the lateral retinaculum.

🔎 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗜𝗻𝘀𝗶𝗴𝗵𝘁: This case highlights the importance of addressing both the cartilage defect and biomechanical contributors to patellofemoral joint stress. The combination of membrane-based cartilage repair and soft tissue realignment offers a comprehensive approach to managing complex patellar cartilage lesions.

𝗪𝗵𝗮𝘁 𝘄𝗮𝘀 𝘆𝗼𝘂𝗿 𝗹𝗮𝘀𝘁 𝗰𝗮𝘀𝗲 𝘆𝗼𝘂 𝘁𝗿𝗲𝗮𝘁𝗲𝗱 𝘄𝗶𝘁𝗵 𝗔𝗠𝗜𝗖® 𝗖𝗵𝗼𝗻𝗱𝗿𝗼-𝗚𝗶𝗱𝗲®?

22/05/2025

🦶 A new case report presents immunohistochemical analysis of tissue samples following AMIC® for osteochondral lesions in the talus, demonstrating progressive transformation to hyaline-like cartilage over 14 to 36 months.

A big 🙏 to the authors: Fabian Krause, Helen Anwander and Schäfer Birgit!

Read the full article with the link in our bio!

08/05/2025

Only two weeks left to join top experts and enhance your surgical expertise! 🙌

Elevate your skills at the 2nd Young Academy on Foot & Ankle Surgery led by the two chairmen Mario Herrera Perez and Sergio Tejero.

📅 May 22-23, 2025 📍Sevilla 🇪🇸

👉 Register now and secure your spot via

01/05/2025

We're sharing a complex case for the 𝗖𝗮𝗿𝘁𝗶𝗹𝗮𝗴𝗲 𝗜𝗺𝗮𝗴𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗠𝗼𝗻𝘁𝗵 𝗔𝗽𝗿𝗶𝗹 𝟮𝟬𝟮𝟱, that Joan Freitas with his team was facing: a 58-year-old woman with chronic left knee pain, associated with multiple meniscal tears, chondropathy and possible ACL involvement.

Following a thorough evaluation (telemetry and MRI), a comprehensive and personalized surgical plan has been designed:

🛠️ ACL reinsertion and re-tensioning with anchors
✂️ Meniscal reshaping and repair
🧬 Biological augmentation with Chondro-Gide® (AMMR® meniscal wrapping)
🔗 Meniscocapsular ligamentoplasty
✨ Chondroplasty of the medial femoral condyle with Chondro-Gide® (AMIC®)
📍 Posterior root reinsertion of the lateral meniscus

𝗧𝗵𝗲 𝗴𝗼𝗮𝗹: to relieve pain, restore function, and improve our patient's quality of life.

Chondro-Gide® played a key role in enabling the surgical team to provide advanced biological solutions. 𝗪𝗵𝗮𝘁’𝘀 𝘆𝗼𝘂𝗿 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝘆 𝗶𝗻 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝗰𝗮𝘀𝗲𝘀 𝗹𝗶𝗸𝗲 𝘁𝗵𝗮𝘁?

17/04/2025

🌟 Exciting Days at the Laboratory Skills Course! 🌟

Congratulations to the Course Directors Jos Malda, Roel JH Custers, and Jasmijn Korpershoek for putting together an exciting program!
Participants enjoyed insightful lectures on chondrocytes, cartilage ECM, in vitro and in vivo models, and cutting-edge bioprinting technologies. The hands-on lab sessions featured cell seeding on a collagen membrane, bioprinting, on-chip systems, and cartilage and bone scoring.
Participants had the opportunity to see the fantastic infrastructure of the labs at UMC Utrecht and the Regenerative Medicine Centre Utrecht. 🏥🔬

31/03/2025

Off to new heights with Chondro-Gide®! ⛷️

Our this month’s Cartilage Image of the Month speaks almost for itself. Alexandra Schöllkopf (Germany) explored the mountains of Georgia (Miketi Mountain, Gudauri) on 3.200 meters above sea level and was ready enough in case of a cartilage defect. 😉

As high as Chondro-Gide® can go, as high is the pile of evidence that speaks for AMIC® in cartilage repair. More than 140 peer-reviewed studies document the good outcomes of AMIC®. 📚

👉 More than 10 years of follow-up data has been published and there is good evidence for AMIC® in the knee, the ankle, the MTP and the hip joint.

29/03/2025

𝗥𝗘𝗠𝗜𝗡𝗗𝗘𝗥: Geistlich is a partner in this Master IBRA Ankle Osteoarthritis Course!

👣 Join us in Basel, Switzerland, on April 4 and 5, 2025!

Explore the latest innovations, discuss representative cases, and engage in hands-on workshops led by Victor Valderrabano. Recommended for senior surgeons and department heads looking to improve patient care. 🏥
Course language is English.

Don't miss out and register via !

18/03/2025

🎉 𝗦𝘂𝗰𝗰𝗲𝘀𝘀𝗳𝘂𝗹 𝗖𝗼𝗺𝗽𝗹𝗲𝘁𝗶𝗼𝗻 𝗼𝗳 𝘁𝗵𝗲 𝗘𝗨 𝗛𝗼𝗿𝗶𝘇𝗼𝗻 𝟮𝟬𝟮𝟬 𝗠𝗘𝗙𝗜𝗦𝗧𝗢 𝗣𝗿𝗼𝗷𝗲𝗰𝘁 🎉

We are thrilled to announce the 𝘀𝘂𝗰𝗰𝗲𝘀𝘀𝗳𝘂𝗹 𝗰𝗼𝗺𝗽𝗹𝗲𝘁𝗶𝗼𝗻 of the 𝗠𝗘𝗙𝗜𝗦𝗧𝗢 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 - Meniscal Functionalised Scaffold to Prevent Knee Osteoarthritis Onset After Meniscectomy.

During yesterday’s 𝗳𝗶𝗻𝗮𝗹 𝗿𝗲𝘃𝗶𝗲𝘄 𝗺𝗲𝗲𝘁𝗶𝗻𝗴, the work done in the project’s final phase was presented and discussed with EC representatives.

The 𝗠𝗘𝗙𝗜𝗦𝗧𝗢 project is a collaborative effort involving 𝟭𝟯 𝗽𝗮𝗿𝘁𝗻𝗲𝗿𝘀 across eight European countries. Our 𝗴𝗼𝗮𝗹 is to 𝗽𝗿𝗲𝘃𝗲𝗻𝘁 𝗢𝗔 𝗮𝗳𝘁𝗲𝗿 𝗺𝗲𝗻𝗶𝘀𝗰𝗲𝗰𝘁𝗼𝗺𝘆 using 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝘃𝗲 𝗯𝗶𝗼𝗮𝗰𝘁𝗶𝘃𝗲 𝗺𝗮𝘁𝗲𝗿𝗶𝗮𝗹𝘀. 🤝

In the final phase, 𝗻𝗼𝘃𝗲𝗹 𝗰𝗼𝗮𝘁𝗶𝗻𝗴 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝗶𝗲𝘀 were used to 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹𝗶𝘇𝗲 resorbable and non-resorbable meniscal implants. These implants were then tested in vivo in partial meniscectomy models. 🦵

The 𝗿𝗲𝘀𝗼𝗿𝗯𝗮𝗯𝗹𝗲 𝗰𝗼𝗹𝗹𝗮𝗴𝗲𝗻 𝘀𝗰𝗮𝗳𝗳𝗼𝗹𝗱 produced by Geistlich and functionalized by Tissue Click was tested by the University Hospital Regensburg team. Meanwhile, 𝗻𝗼𝗻-𝗿𝗲𝘀𝗼𝗿𝗯𝗮𝗯𝗹𝗲 𝗺𝗲𝗻𝗶𝘀𝗰𝗮𝗹 𝗶𝗺𝗽𝗹𝗮𝗻𝘁𝘀 from Active Implants and ATRO Medical, functionalized by Tissue Click and USC, were tested by the Humanitas University team.

Analysis of joint tissues and explanted devices indicates that Tissue Click’s biomimetic, nanostructured coating may provide protection to articular cartilage following meniscectomy. In addition, this 𝗰𝗼𝗮𝘁𝗶𝗻𝗴 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 has proven to be both easily 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝗯𝗹𝗲 to meniscal devices and 𝘀𝘁𝗲𝗿𝗶𝗹𝗶𝘇𝗮𝗯𝗹𝗲.

⌚ Looking back over the past 5.5 years, it's incredible what the MEFISTO consortium has accomplished.

Geistlich is very proud to be a partner and coordinator in this multidisciplinary project that is dedicated to find new ways to help patients overcome the adverse effects of meniscectomy. From the initial project idea to the final report, SCIPROM Sàrl has always provided great support in management, dissemination and communication. 💙

28/02/2025

𝗛𝗼𝘄 𝘄𝗼𝘂𝗹𝗱 𝘆𝗼𝘂 𝘁𝗿𝗲𝗮𝘁 𝘁𝗵𝗶𝘀 𝗽𝗮𝘁𝗶𝗲𝗻𝘁?

🖼️ Our this month’s Cartilage Image of the Month is coming from Kailash Devalia, UK.

👉 Freiberg’s disease is a rare condition affecting the metatarsal head, often leading to pain and functional impairment. We present a case of a 17-year-old female who initially presented with persistent pain and stiffness in her left second toe, unresponsive to conservative management. MRI confirmed Freiberg’s disease of the second metatarsal head.
Due to failure of nonoperative treatments and significant impact on daily activities, she underwent the AMIC® procedure with calcaneal bone grafting as a joint-sparing approach, reserving arthroplasty as a potential future option.

🙌 The patient experienced complete pain relief and returned to full daily and recreational activities within six months postoperatively. One year later, she developed Freiberg’s disease of the second metatarsal of the contralateral foot and underwent the same surgical procedure. Serial postoperative imaging at 1, 3, 5, and 7 years demonstrated stable results, with near-complete remodeling of the metatarsal head and no need for revision surgery.

💡 This case highlights the efficacy of the AMIC® technique with bone grafting as a durable joint-preserving strategy for Freiberg’s disease, offering excellent long-term outcomes.

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About us

Geistlich Surgery produces innovative bio-derived matrix products for bone and cartilage, including Orthoss®, Orthoss Collagen®, and Chondro-Gide®. Our products leverage the body’s own healing potential to regenerate bone and cartilage. Our focus is on helping people maintain and regain their quality of life.

Geistlich Surgery is a business unit of Geistlich Pharma AG, which is headquartered in Switzerland. Entirely family owned since 1851, the company develops, produces, and markets medical devices for regenerative medicine and pharmaceuticals. From research and development to marketing, our operations are fully integrated under one roof, which enables us to oversee and optimize all levels of our business.