26/02/2026
Retinal vascular features of Beta-Thalassemia captured by UWF full range SS-OCTA!
A 14-year-old girl presented with bilateral vision loss for 3 months was diagnosed as Beta-thalassemia by genetic testing. Ultra-widefield SS-OCTA images revealed extensive nonperfusion areas involving macular area in her both eyes. High-resolution ultra-widefield OCT B-scan images showed clearly hyperreflective inner retina in macula with absence of flow signals, demonstrating the ischemia retinal tissue corresponding to the nonperfusion areas. This patient underwent hematopoietic stem cell transplantation and long-term monitor of retinal perfusion.
This case was published in , authored by Dr. Xinyu Zhao, etc. team of Prof. Guoming Zhang from Shenzhen Eye Hospital.
A 400kHz speed swept source OCTA ( , TowardPi Medical) was used in this case to reveal details of retinal vasculatures with exquisite resolution in an ultra-wide field, providing a convenient and effective method for early diagnosis, decision making and long-term disease management.
Link to original text:
https://www.aaojournal.org/article/S0161-6420(25)00601-3/fulltext
A 14-year-old girl presented with bilateral vision loss for 3 months. Ultra-widefield swept-source OCT angiography (BM-400K BMizar, TowardPi Medical Technology; 160°) revealed extensive areas of nonperfusion, particularly involving the macular area (A, D). Widefield B-scans (24 mm) of both eyes dem...