TowardPi

05/08/2025

The impact of magnification-correction on glaucoma parameters in children and adolescents with refractive errors by using UWF SS-OCT！
Research recently published in observed and analyzed the characteristics of optic disc parameters, circumpapillary retinal nerve fiber layer (cpRNFL), and macular ganglion cell complex (GCC) thickness in children and adolescents aged 4–17 years with refractive errors using magnification-corrected swept-source optical coherence tomography (SS-OCT).
286 refractive error subjects (286 eyes) were included in this research. The results confirmed that ocular magnification had an impact on the actual position of the measurement ring on the retina around the optic disc and the size of the measurement area. Before magnification correction, the mean cpRNFL thickness was positively correlated with SE and negatively correlated with AL. No significant correlations were observed between optic disc and rim area and spherical equivalent (SE) or AL.
After magnification correction, macular GCC thickness demonstrated a negative correlation with increasing myopic degree and AL elongation, while optic disc and rim areas showed positive correlations. However, no significant correlation was observed in cpRNFL thickness. Therefore, the effects of magnification correction, AL, and SE should be taken into consideration when interpreting optic disc-related parameters and GCC thickness in children and adolescents.
A 400kHz speed swept source OCTA ( , TowardPi Medical) was used in this study to achieve high-resolution ultrawide field OCTA images with comprehensive glaucoma parameters. Ocular magnification correction formula is available on device, giving calibrated OCT data which shows high concordance with MRI measurements.
This research is authored by Dr. Jingyu Mu, Dr. Jing Wei, etc. team of Prof. Junguo Duan from Ineye Hospital of Chengdu University of TCM.
Link to original text：
https://www.sciencedirect.com/science/article/pii/S1572100025001097

01/08/2025

Connection between arterial pressure and arteriolar diameter captured by UWF SS-OCTA！
Research recently published in investigated the metrics of retinal arterioles and venules based on the en face images of the superficial retina using UWF SS-OCTA and assessed their relationships with specific systemic parameters in a normal sample.
Retinal arterioles and venules were manually segmented and distinguished from the disc margin based on 24mm x 20mm superficial retinal OCTA images. ACartery (averaged caliber of retinal artery) and ACvein (averaged caliber of retinal vein) were calculated separately according to vessel density and skeletonized vessel density of artery and vein. The results revealed a significant negative impact of real-time mean arterial pressure (MAP) on averaged vessel caliber, especially ACartery, indicating that retinal arteriolar caliber is capable of predicting real-time systolic blood pressure.
A 400kHz speed swept source OCTA ( , TowardPi Medical) was used in this study to achieve high-resolution ultrawide field OCTA images with precise and automatic segmentation algorithm.
This research is authored by Dr. Yuchen Li, etc. team of Prof. Jianqin Lei from First Affiliated Hospital of Xi’an Jiaotong University.
Link to original text：
https://www.ophthalmologyscience.org/article/S2666-9145(24)00215-X/fulltext

29/07/2025

Acute posterior multifocal placoid pigment epitheliopathy captured by 400kHz OCT
"Toward Pi，see better IN EYE!"
Golden Signature Series of TowardPi . Endorsement and courtesy: Prof. GuoPing Wang, Ineye Hospital of Chengdu University of TCM, Sichuan, China

24/07/2025

Cover story！True exfoliation syndrome captured by full range AS-OCT！
A wonderful case recently published on the cover of captured a true exfoliation syndrome patient with 100kHz full range swept source AS-OCT ( ,TowardPi ).
This 78-year-old female patient presented delamination of the anterior lens capsule (ALC) with a nuclear cataract in her right eye. A floating, wavy edge of the delaminated anterior layer of the ALC in the inferior nasal quadrant was observed with slitlamp. On 15mm ultra deep high-resolution AS-OCT image, the detailed structure inside the cataract could be observed clearly including the delaminated ALC. The floating membrane was confirmed connecting to the ALC.
This case was authored by team of Prof. Wen Xu from Eye Center of the Second Affiliated Hospital.
Link to original text:
https://journals.lww.com/jcrs/citation/2025/06000/true_exfoliation_syndrome__a_case_study_with.16.aspx

22/07/2025

Decreased choroidal thickness associated to early neurodegeneration in NDR detected by UWF full range SS-OCTA!
Research recently published in identified associations between choroidal alterations and the reduction of peripapillary retinal nerve fiber layer (pRNFL) thickness in diabetes without diabetic retinopathy (nondiabetic retinopathy, NDR) by using UWF SS-OCTA.
The results revealed significant reductions in perifoveal ChT (choroidal thickness), CVI (choroidal vascular index) and pRNFL thickness in patients with NDR, while an increase in CSI (choroidal stromal index) was observed. Notably, ChT was significantly correlated with pRNFL thickness, suggesting that ChT could serve as a predictor of retinal neurodegeneration in NDR.
A 400kHz speed swept source OCTA ( , TowardPi Medical) was used in this study to quantify choroidal changes in three-dimension. Comprehensive choroidal parameters, including CVI, CVV, CSV, CSI and choroidal thickness, can be analyzed on the device with high reproducibility.
This research is authored by Dr. Zhenping Li, Dr. Fan Yang, etc. team of Prof. Yuqing Lan from Sun Yat-sen Memorial Hospital.
Link to original text：
https://journals.lww.com/retinajournal/abstract/2024/08000/associations_between_choroidal_alterations_and.2.aspx

83 patients with NDR and 124 eyes from 82 matched healthy controls. Ultra-widefield swept-source optical coherence tomography angiography was used to automatically measure retinal and choroidal thickness (ChT), retinal vascular density, and choroidal vascular metrics. Data were analyzed using Studen...

18/07/2025

Proliferative diabetic retinopathy captured by 400kHz OCTA
“Leader of industry, Nation's pride;
Insight of doctor, Patients' gospel.”
Golden Signature Series of TowardPi . Endorsement and courtesy: Prof. Jie Zhong, Sichuan Provincial People's Hospital, Chengdu, China.

16/07/2025

TowardPi at 2025 CSCRS. 1 big exhibition booth, 1 surgery broadcast, 2 satellite symposium. OCT, Biometry, Microscope… together we improve the management of Cataract and Refractive Surgery.

14/07/2025

Confident IOL repositioning surgery under intraoperative SS-OCT！
A severe corneal degeneration patient with extensive corneal neovascularization and corneal opacification was found IOL dislocated. In the past, repositioning surgery for such kind of patients could be complicated and probably massive wound could not be avoided.
Now with digital navigation surgical microscope ( , TowardPi Medical), 100kHz intraoperative SS-OCT with 12mm scan-depth provides a dynamic view of panoramic anterior chamber with high resolution during surgery without time-delay. The dislocated IOL haptic was revealed clearly (fig 1. iOCT image, yellow arrow) and repositioned easily with the guide of intraoperative SS-OCT (fig 2).
“Performing such kind of complex surgery in the past was like groping in the darkness. Now, provides real-time, high-resolution intraoperative imaging - effectively granting surgeons tomographic visualization capability during complex cataract surgeries.”
Case courtesy: Prof. Wen Xu from Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University.

*TowardPi microscope is not cleared by CE/MDR or FDA yet.

04/07/2025

A 61-year-old woman African descendant with diagnosis of Sickle Cell Retinopathy (SCR) (Figure 1A) was studied by Toward-Pi BMizar Swept-Source 400 KHz Widefield Optical Coherence Tomography Angiography (WF-OCTA) to assess vitreoretinal anomalies detected 20 years after argon laser photocoagulation....

03/07/2025

Successful completion of the 13th International Distributor Training in TowardPi Shanghai Business Center. It’s with great pleasure having teams from BJC (Thailand), Bon Optic (Germany), Focus Mercantile (Hong Kong) and Nikon Solutions (Japan). Congrats everyone on your certification. The highest score winner of this round of application test goes to: Mr. Worapat Trekitwattanakul from BJC.

01/07/2025

Three-dimensional choroidal changes in DR quantified by UWF SS-OCTA！
Research recently published in investigated three-dimensional choroidal characteristics in different stages of diabetic retinopathy (DR) and determined the effect of panretinal photocoagulation (PRP) by using UWF SS-OCTA.
192 treatment-naïve DR patients, 42 PRP-treated DR patients and 56 healthy controls were included in this study. Results revealed that choroidal thickness (CT), choroidal vascular and stromal volume (CVV/a and CSV/a) decreased in full range of DR (without treatment), while choroidal vascularity index (CVI) decreased only in the peripheral area. Interestingly, choroid was thinning in no-DR (NDR) and mild NPDR, followed by an increased trend in moderate and late stages of DR. Meanwhile, non-perfusion area (NPA) was positively associated with CT, CVV/a, and CSV/a in moderate and late stages of DR suggesting that increased expression of VEGF might be a significant factor in choroidal thickening. After PRP, choroidal parameters decreased while an increase of CVI in the central area was observed, suggesting that PRP treatment could contribute to the redistribution of choroidal blood flow and improve the perfusion of the macula.
A 400kHz speed swept source OCTA ( , TowardPi Medical) was used in this study to quantify choroidal changes in three-dimension. Based on AI-assisted segmentation algorithm and built-in software, comprehensive choroidal parameters, including CVI, CVV, CSV, CSI and choroidal thickness, can be analyzed on the device with high reproducibility.
This research is authored by Dr. Zhaoxia Zheng, etc. team of Prof. Xiaobing Yu from Beijing Hospital.
Link to original text：
https://www.sciencedirect.com/science/article/abs/pii/S0026286225000512

27/06/2025

Corneal neovascularization secondary to trauma captured by 400kHz OCTA
“TowardPi brings us "stunning" ultra-high-speed full range wide-field OCT Angiography technology, which has become a powerful tool to help physicians diagnose diseases. It also represents the leading technical level of medical equipment from China.”
Golden Signature Series of TowardPi . Endorsement and courtesy: Prof. YiQi Chen, Zhejiang Provincial People's Hospital, Hangzhou, China