15/03/2026
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Hormones play a vital role in many disorders: thyroid conditions, diabetes, and some rare diseases. As World Hormone Day is approaching, at Thyroid Federation International, we want to draw attention to hormone health and hormonal dysfunctions.
📍 Hypothyroidism is the most common clinical condition of thyroid hormone deficiency, and, if left untreated, can lead to adverse health effects on multiple organ systems, with the cardiovascular system as the most robustly studied target.
📍 The onset of hypothyroidism is insidious in most cases, and symptoms may present relatively late in the disease process.
❗ Some signs, such as tiredness, are often mistakenly attributed to the normal course of aging or a busier period in life.
❗It is important to understand the progressive nature of symptoms.
📍 Hypothyroidism is primarily categorized as primary and secondary hypothyroidism. In primary hypothyroidism, the thyroid gland cannot produce adequate amounts of thyroid hormone, with Hashimoto's disease being the most common cause in iodine-sufficient regions.
Other conditions may also lead to primary hypothyroidism:
📍 Postpartum thyroiditis affects nearly 10% of women and often presents 8 to 20 weeks after the delivery of the infant.
📍 Treatment with radioactive iodine to manage Graves' Disease usually results in permanent hypothyroidism in about 80% to 90% of the patients within 8 to 20 weeks after treatment.
📍 Subacute granulomatous thyroiditis, also known as de Quervain's disease
📍 Thyroid surgery
📍 Radiotherapy of the head or neck area
📍The antibodies that cause Graves' disease hyperthyroidism can also be present with a hypothyroid condition. Graves' antibodies in hypothyroid patients should be checked, as many of these cases are not detected until the patient develops hyperthyroid symptoms, or Graves dermopathy, or Thyroid Eye Disease.
The less commonly seen secondary, tertiary (central) hypothyroidism results from abnormal pituitary gland or hypothalamus function.
Why early diagnosis matters?
❗ Hypothyroidism, if untreated, may negatively affect female reproductive health, causing disrupted ovulation and issues with fertility. Early diagnosis and treatment are essential.