Reversing PKD - Health Coaching

15/05/2026

What if the next big PKD research lead comes from the patient community?

In this clip, Dr. Beno Freedman explains that the PKD RRC is interested in hearing from people who have molecule or treatment ideas — including “off-the-wall” concepts that have not yet been tried in PKD.

This is such an important shift: patients are not just waiting on research anymore. They can help ask better questions, point researchers toward overlooked ideas, and bring real-world curiosity into the scientific process.

Full episode here: https://www.youtube.com/watch?v=vglWM2pFIwg

14/05/2026

What makes a stem cell become a kidney cell — and not a liver cell, heart cell, or something else entirely?

Watch the full conversation on the Reversing PKD Podcast:
https://www.youtube.com/watch?v=vglWM2pFIwg

In this clip, Dr. Benjamin “Beno” Freedman explains one of the most fascinating parts of kidney organoid research: scientists can guide pluripotent stem cells into becoming tiny kidney-like structures in a dish.

And the wild part?

Sometimes the difference between creating kidney tissue and creating beating heart cell clusters can come down to the dose of the same signaling trigger.

For PKD research, this matters because these “mini kidneys” can form cysts and give scientists a human model to study what is actually happening in Polycystic Kidney Disease — outside the body, but much closer to real tissue than simple cell cultures.

This is where the future of PKD research gets very interesting.

02/05/2026

Fiona Chin, whose podcast I recently appeared on, has synthesized much of what we talked about in a new article summarizing and expanding on my stance regarding Endotoxin as a necessary trigger for PKD. A very interesting read if this is new to you!

Full Podcast: https://www.youtube.com/watch?v=gF02MeaeLXk

Explore the connection between polycystic kidney disease (PKD), gut health, and cancer risk. Learn how the gut–kidney axis, inflammation, and the microbiome may influence disease progression and long-term outcomes.

30/04/2026

What if PKD cyst growth wasn’t just an inevitable progression, but actually had a physical “off-switch”? 🧬
Full Interview: https://www.youtube.com/watch?v=gF02MeaeLXk

23/04/2026

Researchers tried to force PKD cysts to grow in a petri dish using injury and chemicals, but nothing happened. They couldn't get them to grow until they added this one specific ingredient. 🧪
Full Interview: https://www.youtube.com/watch?v=gF02MeaeLXk

15/04/2026

We all thought ketosis was the finish line, but we might be missing the most dangerous part of the entire equation. 🧠
Full Interview: https://www.youtube.com/watch?v=gF02MeaeLXk

13/02/2026

🥩 The best cooking fat is basically free (and it’s not seed oil).

Ask your beef guy for fat trimmings. They often throw it out. Grass-finished is mandatory here. Then turn it into tallow with almost zero effort:

✅ How to render tallow (lazy + clean method):

Pack the slow cooker to the brim with fat (it shrinks).

Set to Auto/Low and let it go ~15–24 hours.

Flip/stir once midway so the top renders too.

Strain through a sieve/funnel into clean mason jars. They sterilize themselves.

Let it cool — it turns solid and seals when the lid pulls in.

From ~8 kg / 16 lb fat you’ll get about 2.5 liters of tallow. That’s months of frying.

🔥 High-heat stable. Cheap. No seed oils.
This is how you combat high butter prices.

16/11/2025

Still haven’t changed your diet for PKD?
I get it – life’s busy. Work, family, everything else.
It’ll all work out eventually… or will it? 🤔

13/10/2025

🔥 Why High-Carb Diets Are a Problem for PKD

Your cyst cells aren’t just growing randomly — they’re addicted to glucose.

🍬 Here’s what happens:
The cells lining your cysts are stuck in a continuous growth mode, and their main fuel is glucose.
Meanwhile, your healthy cells can easily switch to burning fatty acids and ketones for energy.

🥑 So when you lower glucose (with a ketogenic or Bulletproof-style diet),
you starve the cysts while nourishing your healthy cells.

That means you’re not just “cutting carbs” — you’re pumping the brakes on cyst growth.
Over time, this can slow or even partially reverse cyst expansion.

💡 Action step:
If you haven’t yet — start a PKD-proof ketogenic diet (based on the Bulletproof roadmap).
Fuel your healthy cells. Starve the cysts.

28/08/2025

😵 Cravings hit out of nowhere? Don’t panic.

👉 Most cravings = protein deficiency 🍗💪.
Check: did you hit your protein target yet? If yes, maybe you just need more healthy fats 🥑🧈.

⏱️ During fasting? Bulletproof coffee ☕️ keeps you satisfied.
💡 Deep fast? Try my zero-calorie craving hack: warm water + 🍎 apple cider vinegar + 🌿 cinnamon + monk fruit/stevia = cravings crushed.

Your body is smart — give it what it really needs.

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