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The Good Doctor, Frankfurt (2025)

11/09/2025

Lucas Jemeljanova, a 13-year-old boy from Belgium, became the first person in history to be cured of terminal brain cancer after being diagnosed with diffuse intrinsic pontine glioma (DIPG), one of the deadliest childhood tumors. Doctors had given him less than a year to live, but a groundbreaking personalized treatment completely eradicated his cancer. His survival marks a historic medical breakthrough and brings hope for future tailored cancer therapies.

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10/09/2025

❤️Study shows fasting protects against strokes and heart attacks by reducing blood clot formation.

What and *when* you eat are both critically important.

New research has uncovered a promising link between intermittent fasting and reduced blood clot risk, offering potential benefits for people with cardiovascular concerns.

The study, published in Life Metabolism, found that intermittent fasting inhibits platelet activation—a key trigger in clot formation—by boosting levels of indole-3-propionic acid (IPA), a metabolite produced by gut bacteria. Using blood samples from 160 coronary artery disease patients and mouse models, researchers showed that participants who followed a 10-day intermittent fasting routine had higher levels of IPA and a marked reduction in platelet aggregation.

These findings suggest that the gut microbiome plays a central role in how fasting influences the body’s natural clotting mechanisms.

The mice in the study also experienced reduced heart and brain damage after simulated heart attacks and strokes, further highlighting the protective potential of fasting. IPA appeared to mimic the effects of clopidogrel, a common antithrombotic medication, and even worked synergistically when both were combined.

The researchers found that gut bacteria—specifically Clostridium sporogenes—were essential for producing IPA, indicating a powerful link between gut health and cardiovascular protection. While more research is needed to confirm long-term benefits and broader applicability, experts say intermittent fasting could eventually be integrated as a lifestyle-based therapy alongside traditional medications for reducing heart attack and stroke risk.

source
Zhiyong Qi, Luning Zhou, Shimo Dai, Peng Zhang, Haoxuan Zhong, Wenxuan Zhou, Xin Zhao, Huajie Xu, Gang Zhao, Hongyi Wu, Junbo Ge, Intermittent fasting inhibits platelet activation and thrombosis through the intestinal metabolite indole-3-propionate, Life Metabolism, Volume 4, Issue 2, April 2025,

10/09/2025

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09/09/2025

Athletes are at signiﬁcant risk for atherosclerosis and heart damage. Since athletes need to eat more food, the damage may stem from overstressing their hearts with saturated fat and cholesterol.

Plant-based diets, which are low in cholesterol and saturated fat, may contribute to improved performance, quicker recovery, and long-term health by lowering risk of chronic diseases, including heart disease.

Exercise increases the production of free radicals as we burn through energy. If left unchecked, these free radicals can cause DNA damage. Eating antioxidant-rich plant foods helps protect our bodies from these free radicals.

Researchers have observed DNA damage following ultra-marathon races, as well as after just five minutes of moderate or intense cycling. So, regardless of our athletic level, we can all benefit from eating more plants.

Those eating more plant-based diets may naturally be better able to counter exercise-induced oxidative stress due to the higher intake of antioxidant-rich foods.

Plant foods average 64 times more antioxidants than animal products like meat (including fish), eggs, and dairy. Additionally, animal protein can have a pro-oxidant effect. It’s not just about what we’re eating less of—saturated fat and cholesterol—but what we’re eating more of: the phytonutrients, which are found only in plants.

Long term, a plant-based diet can be beneficial for both endurance performance and health.
For more on how specific foods can enhance athletic performance and health, check out the our athletes topic page at nutritionfacts.org/topics/athletes

PMID: 30634559, 16336008, 15059637, 20839226, 20845212, 20096093

09/09/2025

🧠 Study finds sugar-coated proteins sabotage your brain’s defenses, driving Alzheimer's disease.

In a breakthrough study from Johns Hopkins Medicine, scientists have identified a sugar-studded protein that could play a critical role in the development of Alzheimer’s disease.

By examining brain tissue from people who had died with Alzheimer’s, researchers discovered a unique glycoprotein—named RPTP zeta S3L—that connects with the microglial receptor CD33, a protein known to impair the brain’s ability to clear harmful plaques when overactivated.

This glycoprotein’s glycan portion, sialylated keratan sulfate, appears to bind with CD33 and potentially disables the brain’s “clean-up crew,” allowing toxic proteins like amyloid and tau to accumulate. The team found RPTP zeta S3L was over twice as abundant in Alzheimer’s-affected brains, marking it as a potential driver of disease progression.

This discovery opens a promising path toward new treatments and diagnostic tools for Alzheimer’s. If researchers can find a way to block RPTP zeta S3L from activating CD33, they may be able to restore the brain’s ability to remove harmful proteins before they build up to dangerous levels. The study also raises the possibility of using this glycoprotein as an early biomarker for Alzheimer’s, improving detection and intervention strategies. As the researchers continue to unravel the structure of this molecule, they hope to better understand how it influences brain immune responses and how it might be targeted therapeutically.

Source: Gonzalez-Gil Alvarenga, A., Porell, R., Fernandes, S., Maenpaa, E., Li, T. A., Li, T., Wong, P., Yu, Z., Orsburn, B., Bumpus, N., Aoki, K., Tiemeyer, M., & Matthew, R. (2022). Journal of Biological Chemistry.

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09/09/2025

Scientists have created a smart menstrual pad prototype that can detect disease biomarkers in period blood, offering a noninvasive way to screen for conditions like inflammation and ovarian cancer. The pad uses a color-changing test strip to identify proteins such as CRP, CEA, and CA-125. Early trials showed promising accuracy compared to standard lab tests, with no loss of comfort for users.

09/09/2025

Dry fasting, also known as absolute fasting, is a technique that involves abstaining from all food and liquids.

It has many potential benefits, including:
-It can help regulate blood sugar.
-It can help burn fat.
-It can help support liver function.
-It can help reduce inflammation.

If you’re new to fasting, experiment with intermittent dry fasting for a few hours and pay attention to how your body reacts.

Note how you feel after your first few fasting sessions, and once you get comfortable, transition into a 12-hour or 14-hour dry fasting period.

Then, when you break your fast, drink plenty of liquids. Kefir and bone broth are good choices!

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09/09/2025

A new study has uncovered an alarming trend: cancers once considered diseases of older age are now appearing more often in younger adults. Rates of breast, colon, kidney, and uterine cancers are rising sharply among people under 50, raising urgent questions about the causes behind this shift.

Researchers believe that lifestyle factors such as diet, obesity, alcohol use, and lack of physical activity may be contributing, along with possible environmental exposures. Advances in screening and awareness also mean cancers are being detected earlier, but the steady rise among younger age groups points to deeper changes in health patterns.

This trend is sparking calls for earlier screening, especially for colon and breast cancers, which traditionally began later in life. Doctors emphasise the importance of knowing your family history, staying active, eating a balanced diet, and not ignoring unusual symptoms.

The findings serve as a wake-up call that cancer is no longer just a disease of old age, but one that younger generations must take seriously.

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