10/10/2025
Complicated urinary tract infections denote an important research field for new antibiotics against Gram-negative pathogens. There is, however, increasing concern that this disease entity is too vaguely defined, leading to heterogeneous study populations and risk of bias. We analysed researchers' adherence to the US Food and Drug Administration (FDA) guidance on complicated urinary tract infection and assessed risk of bias using a three-step procedure 📒
We are pleased to announce our paper: Bjerklund Johansen TE, Bahrs C, Bruyere F, Cai T, Joseph A, Köves B, Livermore DM, Oliva A, Soriano A, Wagenlehner F, Zahl PH, Etienne M; cUTI Consensus Group. Consensus position statement on advancing the classification of patients and tests of cure in studies of antibiotic treatment of complicated urinary tract infections. Lancet Infect Dis. 2025 Oct;25(10):e605-e618. doi: 10.1016/S1473-3099(25)00142-2.