Anova Institute for Regenerative Medicine

Anova Institute for Regenerative Medicine ANOVA Institute for Regenerative Medicine is a clinic located in Germany that offers stem-cell based treatments, including a full diagnostic work-up.

ANOVA Institute for Regenerative Medicine is a Germany-based clinic that offers stem-cell based treatments, including a full diagnostic work-up.

Dr. Nicole Kühl is a central figure behind ANOVA IRM’s scientific and regulatory foundation. With decades of experience ...
09/01/2026

Dr. Nicole Kühl is a central figure behind ANOVA IRM’s scientific and regulatory foundation. With decades of experience in cell biology, GMP, and advanced therapy medicinal products (ATMPs), she has been instrumental in turning scientific innovation into clinically applicable, regulator-approved therapies.

Her career combines academic excellence with hands-on responsibility in highly regulated environments. Among her key milestones:

• PhD (Dr. rer. nat.) in Cell Biology, University of Bremen (magna cm laude)
• Postdoctoral Researcher, University & Academic Hospital Groningen
• Research Instructor in Biochemistry & Cell Biology, Jacobs University Bremen
• Former Director, PromoCell Academy (ISO-certified GMP training institution)

In 2016, together with Dr. mult. Michael K. Stehling, she co-founded ANOVA IRM, creating the regulatory and quality framework that enables safe, science-driven regenerative medicine.

01/01/2026

As we begin the new year, we would like to thank our patients and partners for their continued trust. We wish you a healthy and successful year ahead.

Not all regenerative challenges are the same.• BMC may be suitable when the goal is to support local tissue repair, for ...
19/12/2025

Not all regenerative challenges are the same.

• BMC may be suitable when the goal is to support local tissue repair, for example in joints or musculoskeletal structures.
• MSC Secretome may be considered when addressing systemic inflammation or signaling dysregulation.

Understanding where the problem originates helps determine how it should be addressed.

Diabetes affects far more than blood sugar. Over time, chronic inflammation and metabolic stress can damage nerves, bloo...
12/12/2025

Diabetes affects far more than blood sugar. Over time, chronic inflammation and metabolic stress can damage nerves, blood vessels, kidneys, and joints, even in people with well-controlled glucose.

At ANOVA, we combine advanced imaging, lab diagnostics, and cell-free regenerative therapies such as stem cell secretome, which delivers bioactive signaling molecules without introducing living cells. These approaches are designed to support tissue repair, modulate inflammation, and promote regenerative processes.

Every therapy begins with a simple step: being there for the patient.At ANOVA IRM, regenerative medicine isn’t just abou...
04/12/2025

Every therapy begins with a simple step: being there for the patient.

At ANOVA IRM, regenerative medicine isn’t just about innovative cell-based approaches, it’s about careful medical responsibility, safety, and individual support at every stage.

From first consultation to follow-up care, our team focuses on one goal: giving each patient the best possible conditions to move forward, with a treatment plan tailored to their situation.

Because progress in medicine is built on both science and people.

BMC is a stem-cell–rich concentrate made from your own bone marrow. We harvest a small sample from the pelvic crest, gen...
27/11/2025

BMC is a stem-cell–rich concentrate made from your own bone marrow. We harvest a small sample from the pelvic crest, gently concentrate the regenerative cell fraction, and inject it precisely where healing is needed.

Our BMC procedure at ANOVA includes:
• Collection: A minimally invasive bone-marrow harvest performed under sterile conditions and medical supervision.
• Concentration: The sample is carefully processed to enrich the stem cells and regenerative growth factors.
• Quality control: Each concentrate is checked on-site to ensure safety and consistency before application.
• Targeted application: The BMC is then delivered with imaging guidance directly into the affected joint or tissue for maximum precision.

Because BMC is autologous (from your own body), it comes with a very low risk of immune reaction and is designed to support repair and reduce local inflammation in orthopaedic and degenerative conditions.

If you’re exploring options to delay or avoid surgery, BMC may be worth discussing in a consultation.

🔗 Learn more: anova-irm.com

Bone Marrow Concentrate (BMC) is a minimally invasive therapy that uses your own regenerative cells to address joint and...
21/11/2025

Bone Marrow Concentrate (BMC) is a minimally invasive therapy that uses your own regenerative cells to address joint and soft-tissue damage.

At ANOVA IRM, we prepare a highly concentrated formulation of your bone marrow in a certified clinical environment, without any cultivation or manipulation.

Every case is evaluated individually to determine whether BMC is the right approach for your condition.

If you're looking for a regenerative alternative to surgery or long-term medication, we're here to guide you.

At ANOVA, every treatment begins with clarity.Our diagnostic work-up combines advanced imaging, detailed lab analysis, a...
13/11/2025

At ANOVA, every treatment begins with clarity.
Our diagnostic work-up combines advanced imaging, detailed lab analysis, and specialist evaluation to uncover the true cause of your pain — not just the symptoms.

Because ANOVA has its own radiology center, we provide advanced imaging with the precision needed to plan truly individualized therapies.

This is how we ensure that regenerative treatments like BMC, Secretome, or targeted interventions are based on data, not guesswork — and tailored to what your body actually needs.



While conventional therapies focus on symptom control, regenerative medicine aims to support the body’s ability to repai...
29/10/2025

While conventional therapies focus on symptom control, regenerative medicine aims to support the body’s ability to repair itself.

At ANOVA, we use the Stem Cell Secretome — the cell-free fraction containing growth factors, cytokines, and exosomes — to modulate inflammation and promote regeneration in the nervous system.

Produced under strict regulation in Germany, our Secretome-based therapy offers a scientifically grounded, safe, and innovative approach to support patients with neurodegenerative conditions such as Multiple Sclerosis.

Knee pain doesn’t have to mean joint replacement.With Bone Marrow Concentrate therapy, we at ANOVA focus on true regener...
26/09/2025

Knee pain doesn’t have to mean joint replacement.

With Bone Marrow Concentrate therapy, we at ANOVA focus on true regeneration, not just symptomatic relief.

If you’re exploring alternatives for knee health, we’re here to help you understand whether this approach is right for you.

👉 Learn more: anova-irm.com/BMC


Not all stem cell therapies are the same.Here’s why ANOVA focuses on the Stem Cell Secretome.
19/09/2025

Not all stem cell therapies are the same.
Here’s why ANOVA focuses on the Stem Cell Secretome.

At ANOVA, we operate our own laboratory directly within the clinic. This is where our stem cell–based products are prepa...
12/09/2025

At ANOVA, we operate our own laboratory directly within the clinic. This is where our stem cell–based products are prepared, stored, and routinely tested for quality. In addition, we work with independent external laboratories to verify results and maintain objectivity.

In Germany, stem cell products are regulated under the Medicinal Products Act (Arzneimittelgesetz). Any institution that manufactures or processes them must obtain an official license and comply with Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) standards. ANOVA has held these licenses since 2018.

Our laboratory and procedures are also subject to continuous oversight by the Ministry of the State of Hesse and the Paul-Ehrlich-Institut, Germany’s federal authority for vaccines and biomedicines. This ongoing supervision is designed to ensure consistent quality and patient safety. In countries without such regulatory frameworks, comparable safeguards are often missing.

Adresse

Strahlenberger Straße 110
Offenbach Am Main
63067

Öffnungszeiten

Montag 09:00 - 17:00
Dienstag 09:00 - 17:00
Mittwoch 09:00 - 17:00
Donnerstag 09:00 - 17:00
Freitag 09:00 - 17:00

Telefon

+4969505000944

Benachrichtigungen

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