08/07/2025
Taurolidine has proven 𝘀𝗮𝗳𝗲 𝗮𝗻𝗱 (𝗰𝗼𝘀𝘁-)𝗲𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 in preventing catheter-related infections and is therefore recommended by international guidelines. (1,2)
⚠️ But infections are not the only type of catheter-related complications that might occur. Patients with vascular-access devices also need protection against occlusion.
👉 That’s why our standard lock solution contains a combination of 𝘁𝗮𝘂𝗿𝗼𝗹𝗶𝗱𝗶𝗻𝗲 𝗮𝗻𝗱 𝟰 % 𝗰𝗶𝘁𝗿𝗮𝘁𝗲 to maintain an adequate flow rate.
For patients at high risk of occlusion, we have developed two more variants with different concentrations of 𝗵𝗲𝗽𝗮𝗿𝗶𝗻 (in addition to taurolidine and citrate). Since TauroLock™-HEP500 entered the market in 2007, it has become the gold standard for haemodialysis patients. (3,4)
☝️ Last but not least, thrombosis is another serious complication that warrants prevention. That’s where TauroLock™-U25.000 comes in: With taurolidine, 4 % citrate, and 25,000 IU 𝘂𝗿𝗼𝗸𝗶𝗻𝗮𝘀𝗲, it provides the strongest protection against severe occlusion and biofilm.
Our portfolio offers a comprehensive range of lock solutions for all central-venous catheters, PICCs, and ports. Designed to make the maintenance of VADs as easy, safe, and cost-efficient as possible.
1) Vernon-Roberts et al. JPEN J Parenter Enteral Nutr 2022. DOI: 10.1002/jpen.2363
2) Pironi et al. Clin Nutr 2020. DOI: 10.1016/j.clnu.2020.03.005
3) German Society of Nephrology (DGfN) 2019.
4) Van Roeden et al. BMC Nephrology 2021. DOI: 10.1186/s12882-021-02519-3