31/10/2025
𝐒𝐡𝐨𝐮𝐥𝐝 𝐁𝐅𝐑 𝐛𝐞 𝐭𝐡𝐞 𝐟𝐢𝐫𝐬𝐭-𝐥𝐢𝐧𝐞 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐟𝐨𝐫 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐰𝐢𝐭𝐡 𝐤𝐧𝐞𝐞 𝐨𝐬𝐭𝐞𝐨𝐚𝐫𝐭𝐡𝐫𝐢𝐭𝐢𝐬?
Osteoarthritis (OA) is among the leading causes of pain and disability worldwide, with the knee being the most commonly affected joint. Current clinical guidelines recommend patient education and neuromuscular exercise, as in the GLA:D Concept (Good Life with osteoArthritis in Denmark), now implemented internationally.
In recent years, blood flow restriction ( ) exercise has been proposed as an alternative to traditional high-load strength training for patients with knee OA – particularly for those who cannot tolerate heavy resistance due to pain, which often reduces adherence (Wang, 2022). These reports align with our practical experience and the feedback we receive from health care professionals during our courses and workshops, highlighting a clear need for additional tools in the OA exercise toolbox – especially for patients who are pain-compromised.
Two recently published studies by a Danish research group (Sørensen et al., 2025 A+B, see refs in comments) compared blood flow restriction resistance exercise (BFR-RE) to a standard neuromuscular exercise (NEMEX) program, both including two hours of patient education.
96 patients with unilateral knee OA completed 12 weeks of training where allocated to either:
1️⃣ BFR-RE (n = 47): 2 sessions/week of unilateral knee extension and leg press (30-15-15-failure) with, 60–80% AOP, ~40 min/session, cuff: Occlude BFR.
2️⃣ NEMEX (n = 49): 2 sessions/week of circuit-based strength training (pelvic lifts, lunges, hip/knee exercises, sit-to-stand, stair climbing), 2–3 sets of 10–15 reps, ~60 min/session.
𝗦𝘁𝘂𝗱𝘆 𝗔 – 𝗣𝗮𝘁𝗶𝗲𝗻𝘁-𝗿𝗲𝗽𝗼𝗿𝘁𝗲𝗱 𝗼𝘂𝘁𝗰𝗼𝗺𝗲𝘀 𝗮𝗻𝗱 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻:
Both groups improved KOOS and Oxford Knee Scores (OKS), but BFR-RE showed a tendency toward greater pain reduction and clinically relevant change. At 12 weeks, BFR-RE produced superior gains in gait speed, stair climbing, sit-to-stand performance, and reduced pain sensitization.
Continued in comments: