Center for Akutforskning

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Center for Akutforskning

Center for Akutforskning er en forskningsenhed ved Aarhus Universitetshospital og Aarhus Universitet

Center for Akutforskning er en forskningsenhed på Aarhus Universitetshospital og Aarhus Universitet.

09/10/2025

⚡️ EUSEM 2025 Vienna, Austria ⚡️

Last week researchers from the Research Centre for Emergency Medicine attended the EUSEM (European Society for Emergency Medicine) 2025 conference in Vienna.

Once again, they joined an international gathering of researchers, clinicians, and students. An inspiring setting to share ideas and reflections, connect with colleagues, grow as a community and explore the latest advances in emergency medicine✨

03/10/2025

🚨 Oral presentation at the 24th Nordic Stroke Society Congress 2025, Tartu

At the congress, Line Bilgrav Nisgaard presented her master’s thesis:
“Symptoms and Referral Patterns of Patients with a Missed Acute Ischemic Stroke: A Danish Multicentre Cohort Study”

👉 Key findings:

Patients with non-specific symptoms (dizziness, headache, nausea, vomiting) were more often admitted to Emergency Departments than Stroke Centres.

These patients experienced significantly longer delays and received reperfusion therapy less frequently.

This work was carried out in close collaboration with supervisors:

Marianne Lisby, PhD, MHSc, RN, Associate Professor in Emergency Medicine
Rolf Blauenfeldt, MD, PhD, Associate Professor in Neurology
Niels Hjort, MD, PhD, Associate Professor in Neurology

Affiliations:
1️⃣ Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus University, Denmark
2️⃣ Department of Neurology, Aarhus University Hospital, Denmark

29/09/2025

🌟 Early DETECTION of inherited cardiomyopathies in the ED 🌟

We are delighted to welcome Heidi Brinkmann Larsen!

Heidi is a medical student and will be joining us as a research year student under the supervision of Professor Bas de Groot.

Her project investigates whether the emergency department could be a suitable setting for early detection of inherited cardiomyopathies. Although these diseases are rare, they can have fatal consequences, making early identification and prevention crucial. The study will focus on younger ED patients with unexplained cardiac symptoms, analyzing genetic variants, ECGs, and questionnaires to assess the prevalence of pathogenic findings.

Welcome Heidi – we look forward to following your exciting project! 🚀

25/09/2025

🌟 Ventilation pauses during in-hospital cardiac arrest 🌟

We are excited to welcome Anna Sommer Harrits to RECEM!
Anna is a 26-year-old medical student from Aarhus University who will begin her research year with us under the supervision of Kasper Glerup Lauridsen, together with co-supervisors Bo Løfgren, Kristian Krogh, and Johannes Wittig.

🫁 Her project focuses on ventilation during cardiopulmonary resuscitation, exploring the optimal chest compression pause duration needed to achieve successful manual ventilations during 30:2 CPR. Using data from the VENT-IHCA study, a prospective multicenter observational study, Anna will combine direct ventilation measurements with CPR quality data from defibrillators to investigate how the duration of chest compression pauses influence ventilation success in adult patients with in-hospital cardiac arrest.

We look forward to an exciting year of research with Anna and to following her contributions to improving cardiac arrest care! 🚀

23/09/2025

🔎 Can Ultrasound Improve Diagnosis of Abdominal Pain in the Emergency Department?

This is the key question that our new PhD student, Ronja Leth, will spend the next three years investigating.

Ronja is training to become a specialist in Emergency Medicine, and during her PhD she will lead a large randomized controlled trial across Danish emergency departments.

In the study, patients with abdominal pain will either receive:
1️⃣ One group receives the standard assessment (medical history, blood tests, physical exam).
2️⃣ The other group receives the same standard assessment together with a bedside ultrasound.

By comparing the tentative diagnoses from emergency physicians with final diagnoses reviewed by an expert panel, Ronja’s research will shed light on whether ultrasound can
improve diagnostic accuracy in the emergency department.

We look forward to following Ronja’s important work! 👩‍⚕️✨

16/09/2025

🚑 Exciting research in progress by Emma Bürgstein, an international research fellow and paramedic from Germany! 👏

Emma is currently visiting our center as part of an international research visit, aimed at studying the impact of CPR coaching in simulated paediatric out-of-hospital cardiac arrest (OHCA).

🌍 Together with Associate Professor Kasper G, Lauridsen and PhD student Johannes Wittig from the Research Center for Emergency Medicine, Emma is leading a simulation-based multicenter randomized trial investigating whether the CPR-Coaching method can help paramedic teams improve CPR quality during paediatric OHCA together with collaborators from Germany, Austria and Canada.

CPR Coaching is a new concept of team members providing real-time coaching and feedback on chest compression quality during CPR. CPR coaching has been developed for the in-hospital context but Emma and her team will assess if CPR Coaching can be transferred to the prehospital setting. This could contribute to improved quality of care and ultimately patient outcomes.

🚀 We are looking forward to seeing the results of the study and to learn more about the potential of CPR Coaching for paediatric OHCA!

12/09/2025

🚑 Who CARES2: Improving Emergency Care for Older Patients 🚑

We are excited to welcome Kasper Hoberg von Benzon, MSc in Health Sciences, as a new PhD student at the Research Center for Emergency Medicine.

The Who CARES2 project aims to improve emergency care for older patients by testing whether ambulance personnel can apply two simple tools: an age-adjusted early warning score and the Clinical Frailty Scale (CFS), to better assess disease severity and frailty before patients arrive at the hospital.

By combining these tools with a holistic, patient-centered approach, the study seeks to:
✅ Improve quality of life for frail older patients
✅ Reduce unnecessary hospital admissions
✅ Lower healthcare costs through more appropriate prehospital care

The project will include training of ambulance staff and a large clinical trial in the Central Denmark Region. With this work, the project aims to contribute to more value-based, personalized emergency care for one of the most vulnerable patient groups.

We look forward to following Kasper’s journey and the important knowledge this project will bring!

09/09/2025

🚨 New publication on patients with pulmonary embolism in Emergency Departments during COVID-19

A new study in Acta Anaesthesiologica Scandinavica investigated whether the COVID-19 pandemic influenced outcomes for patients admitted with pulmonary embolism (PE) to Danish Emergency Departments.

👉 The key finding: no significant difference in 30-day mortality, disease severity at admission, or ICU transfers between the pre-pandemic and pandemic periods.

📌 In short: The COVID-19 pandemic did not impact short-term mortality or acute outcomes for PE patients in the Central Denmark Region.

🔗 Read the full article here: https://pubmed.ncbi.nlm.nih.gov/40828519/

👏 Congratulations to Katarina, Sara, Hans, and Marianne on this important contribution!

05/09/2025

✨ New beginnings at the Research Center for Emergency Medicine ✨

We’re excited to welcome both new PhD students, Research Year students, and Master thesis students who have just started with us!

Looking forward to introducing you to all the new people starting here and to their projects!

Stay tuned! 🚀

25/08/2025

🚨 Adherence to Antibiotic Guidelines in Acute Patients With Suspected Severe Pneumonia

Sanne Schjødt and colleagues have just published an exciting study in Dansk Tidsskrift for Akutmedicin:

🔍 What they found:
Only 38% of patients prescribed the regional “Start package for severe pneumonia” (piperacillin/tazobactam + clarithromycin) actually fulfilled the guideline criteria.
This highlights a substantial gap in guideline adherence and points to overuse of broad-spectrum antibiotics in Danish EDs.

💡 Why it matters:
- Community-acquired pneumonia is a major driver of antibiotic use.
- Overuse of broad-spectrum antibiotics accelerates antimicrobial resistance.
- Results provide concrete insights for Antibiotic Stewardship and implementation of updated pneumonia guidelines.

📖 Read the full open access article here:
👉 https://doi.org/10.7146/akut.v8i1.156720

Congratulations to Sanne and co-authors Marianne Lisby, Lotte Ebdrup, and Marie Kristine Jessen on this timely and clinically important work! 👏

20/08/2025

🔔 Time to ring the bell — twice!

At the Research Center for Emergency Medicine, ringing the bell marks a milestone — and this this week, PhD student Sandra Thun Langsted had every reason to celebrate 🎉
She just published two papers, including her 2nd PhD article

📄 #1: Identifying the optimal thoracentesis training strategy: a randomized non-inferiority study.
Link: https://pubmed.ncbi.nlm.nih.gov/40482565/

Can we train emergency doctors more effectively without taking them away from the clinic?

This multicenter RCT compared traditional instructor-led thoracentesis courses with a blended, self-directed, spaced learning program integrated into clinical work hours.

🔍 Key findings:
✅ Comparable skill acquisition after 2 weeks
✅ Superior skill retention at 3 months with spaced learning
✅ Higher procedural volume in spaced learning group
✅ Better integration into clinical workflows

💡 This study highlights the potential of spaced and self-directed learning in clinical education – especially in a time where resources, supervision and training time are increasingly limited

🧪 In collaboration with: Bo Løfgren, Kasper G. Lauridsen, Søren Helbo Skaarup & Jesper Weile.

🌍 #2: International collaboration with Royal London Hospital
During her research stay, Sandra joined the ED research team at Royal London Hospital led by Ben Bloom and contributed to the DECIPHER study, published in BMJ Health & Care Informatics.
Link: https://informatics.bmj.com/content/32/1/e101433

Goal: Use AI to automate classification of head CT reports for intracranial bleeds (ICB).

Three methods were tested: Text classification program, a commercial NLP tool, and a custom GPT-based LLM

🧠 Highlights:
✔️ 100% sensitivity and 97.4% specificity for the LLM
✔️ 86% reduction in manual review workload
✔️ Outperformed both competing methods

💥 A promising tool for scaling up research and improving data workflows in emergency medicine.

15/08/2025

🚫❤️ The myth of a poor life after cardiac arrest – busted ❤️🚫

Surviving a cardiac arrest can be life-changing – but not necessarily for the worse. A new study from Aarhus University Hospital, Hammel Neurocenter, and international partners finds that 98% of survivors have good functional ability and a quality of life comparable to the general population, even 5–8 years later.

Among the research team is Professor emeritus Hans Kirkegaard from the Department of Clinical Medicine - Center for Emergency Research, who contributed to the project alongside colleagues in Denmark, Finland, and Germany.

📊 Key findings:
✅ 97.8% have good functional ability
✅ Quality of life matches the general population
⚡ 45.5% experience fatigue
💤 24.5% have sleep problems
🧠 52.3% of relatives report cognitive decline in the survivor

🔍 Fear of severe, long-term disability should not be the main reason for declining resuscitation. While some survivors experience fatigue, sleep problems, or cognitive changes, these challenges do not overshadow an overall good quality of life for most.
📚 Read the study in Resuscitation: https://pubmed.ncbi.nlm.nih.gov/40499675/

Adresse

P***e Juul Jensens Boulevard 161
Aarhus
8200

Internet side

https://recem.au.dk/

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