Sociedad Ecuatoriana De Alergia,asma E Inmunologia (SEAAI)

22/01/2026

22/01/2026

How to write a scientific article: A step-by-step guide for beginners,
Publisher ELESVIER (2015)
Find Full-Text here:
https://www.sciencedirect.com/science/article/abs/pii/S1878764915001606
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15/01/2026

AI may help public health researchers track trends that could develop into an outbreak, but these tools should be used to complement traditional research.

14/01/2026

AAAAI celebrates the addition of training on “best practices to prevent, recognize and respond to food-related allergic reactions” for federal school lunch and breakfast programs from today’s signing of the Whole Milk for Healthy Kids Act.

14/01/2026

https://www.linkedin.com/posts/balexander-salazar_esta-revisi%C3%B3n-describe-c%C3%B3mo-elm%C3%BAsculo-esquel%C3%A9tico-share-7416638000882753536-zSRn?utm_medium=ios_app&rcm=ACoAAAnzVNEB1XSvHb-lA1ohH-wtGMRdhwk05ac&utm_source=social_share_send&utm_campaign=facebook

14/01/2026

In 2003, Jean-Michel Claverie made a discovery in bacterial genomics that would change his career trajectory and begin a new era in microbiology. “One day, we found a very strange beast that nobody could characterize,” Claverie, now a semi-retired bioinformatician at the Aix-Marseille University, said, “It was not responding to the regular tests for bacteria.”

Growing in an amoebal host, this ‘beast’ had been isolated from a water-cooling tower in England following a pneumonia outbreak a decade earlier. It looked and acted like a parasitic bacterium, yet it could not be extracted using any established protocols, nor amplified using universal 16S rDNA bacterial primers. It wasn’t until Claverie and his colleagues examined it under a powerful electron microscope that they realized it wasn’t a bacterium at all—it was an enormous virus. “This changed my life, basically,” Claverie recalled.

Lurking in the vast expanse of the ocean and buried deep in the Siberian permafrost, there are giants—not blue whales and mammoths, but giant viruses.

13/01/2026

Fossils of a human ancestor from 773,000 years ago may be near the base of the Homo sapiens lineage, representing a common ancestor of modern humans, Neandertals and Denisovans

13/01/2026

BACKGROUND

MOv18 IgE is a first-in-class IgE antibody targeting FRα, an antigen overexpressed in ovarian and other cancers.1 IgE-based anti-cancer antibodies offer significant advantages, such as the ability to bind strongly to immune effector cells via the FcɛRI receptor and to stimulate tumour-infiltrating immune cells against cancer. In a recent Phase I clinical trial, MOv18 IgE demonstrated promising efficacy, but also triggered transient urticarial skin reactions. The authors aimed to elucidate the immunological basis of these reactions and assess whether they were mediated by allergic mechanisms.

MOv18 IgE is a first-in-class IgE antibody targeting FRα, an antigen overexpressed in ovarian and other cancers...

13/01/2026

CONCLUSION

Eosinophils are sensitive to both sample collection and treatment conditions, while the post-collection release of EDN should be avoided.5 Among the tested blood matrices, the one with the lowest reference interval, mean, and median is considered ideal. According to the manufacturer’s validation data, EDTA plasma emerges as the logical matrix of choice, while serum is the least favourable choice. This study, conducted under common routine practice, confirms the choice of EDTA plasma, although the author’s ranking also proposes that Barricor™ lithium-heparin plasma is the least favourable choice. The manufacturer of the ImmunoCAP™ assay suggests that EDTA inhibits enzymatic processes, whereas heparin is supposed to leave the eosinophils in a less activated state compared to serum. The authors claim that the treatment of samples, the activation by the applied centrifugation conditions, and the separation by the Barricor™ system, is critical. Therefore, the EDN value measured in EDTA plasma more reflects the true EDN concentration in blood. The author’s reference intervals are based on a general hospital population, which includes individuals with both EDN-related and unrelated pathologies, and do not represent a purely healthy cohort.

Eosinophil-derived neurotoxin (EDN), as a biomarker of eosinophilic activity, can be measured in blood matrices such...

13/01/2026

BACKGROUND

Eosinophil-derived neurotoxin (EDN), as a biomarker of eosinophilic activity, can be measured in blood matrices such as serum, ethylenediaminetetraacetic acid (EDTA) plasma, and heparin plasma.1 For unclear reasons, current EDN studies aim to use serum, even though the manufacturer’s assay validation identifies it as the least suitable matrix of choice.2,3 Moreover, the same validation data do not include reference values for adults.4 The goal of this study is to establish EDN reference intervals, means, and medians in different blood matrices in adults, and to argue which blood matrix should be measured for EDN.

Eosinophil-derived neurotoxin (EDN), as a biomarker of eosinophilic activity, can be measured in blood matrices such...

13/01/2026

🔥Manual de redacción científica: cómo escribir manuscritos de forma eficiente y efectiva
✍🏼Alejandro Gustavo Farji-Brener/Víctor Arroyo-Rodríguez2
📚 Editorial: UNAM-ENES (Mérida)/IIES
🔓🧡📥
https://www.iies.unam.mx/libros/Manual-Redaccion-Cientifica_UNAM2025.pdf

13/01/2026

The CDC now recommends that all children receive vaccines for polio, measles, mumps and rubella, chickenpox, Haemophilus influenzae type B, pneumococcal disease, human papillomavirus (HPV), tetanus, diphtheria and pertussis. High-risk groups or populations may also be recommended shots for dengue, hepatitis A, hepatitis B, meningococcal ACWY, meningococcal B and respiratory syncytial virus, or RSV. For other diseases, including rotavirus, COVID and the seasonal flu, the agency suggests people talk to their doctor.

“The data support a more focused schedule that protects children from the most serious infectious diseases while improving clarity, adherence, and public confidence,” acting CDC director Jim O’Neill said in the announcement. The announcement did not cite the data O’Neill referred to.

The U.S. Centers for Disease Control and Prevention is reducing the recommended number of vaccines for children to those that protect against 11 diseases instead of the protections against 17 illnesses that it recommended previously