
20/01/2024
النهاردة هنتكلم شوية عن الكاربيمازول من أهم الأدوية اللى بتعالج فرط نشاط الغدة الدرقية و كمان فيه أزمة كبيرة دلوقتى في توفيره لأنه ناقص، كتير من الروشتات اللى بيبقي مكتوب فيها كاربيمازول بيبقي مكتوب ممكن بال 8 أو 10 حبة في اليوم وممكن توصل 12 حبة كمان ودا لأنه التركيز الوحيد المتوفر في السوق هو ال 5 mg بس ف دا يخلينا نسأل نفسنا ليه مفيش أدوية فيها تركيز أكبر من الكاربيمازول في السوق عشان مشكلة ال adherence و ال compliance للمريض خصوصا انى دورت ولقيت أنه مفيش اي سبب علمي أو صيدلانى يمنع وجود حاجة زى كده
لو حد عنده إجابة ياريت يشاركنا بيها فى الكومنتات.
Today's post is about a question that always confuses me regarding carbimazole, but first here is some information about carbimazole
Carbimazole is a medicine used to treat an overactive thyroid (hyperthyroidism).
dosage:
Adult: Initially, 15-60 mg daily in 2-3 divided doses, titrate dose against thyroid function until euthyroidism is achieved. Maintenance: 5-15 mg daily (may be given as a single dose), adjust dose as needed to maintain euthyroid state. Blocking-replacement regimen: Initially, 20-60 mg daily in combination with levothyroxine. Treatment duration: 6-18 months.
Child: 3-17 years Initially, 15 mg daily adjusted according to response
so after we knew the dose of carbimazole, i didn't find any product in the Egyptian market containing carbimazole higher than 5 mg per tablet so according to the dose, patients may need to take up to 12 tablets per day which is a real problem for patient adherence and compliance.
I saw many prescriptions containing this number of tablets and I searched very much for the reason why there's no drug containing higher dose of carbimazole and if it related to any Pharmaceutical cause but I didn't find any answer so if any one have any answer, you can share it with me and for the pharmacist from the other countries can you tell me if there's drugs containing crabimazole other than 5mg.