Oral & Maxillofacial Pathology - Cairo University

25/02/2026

🌙✨ 𝐑𝐢𝐝𝐝𝐥𝐞 3 ✨🔬

Little bit easier this time… but still for the sharp eyes 👀🔬

22/02/2026

🌙✨ 𝐑𝐢𝐝𝐝𝐥𝐞 𝟐 ✨🔬

🧠 *A little bit harder… for specialists only!* 😄😎

20/02/2026

✨🔬 𝐑𝐢𝐝𝐝𝐥𝐞 𝟏 ✨🔬

19/02/2026

🎉 It is time to have some fun with Ramadan! 😁

Get ready for a series of exciting Oral Pathology riddles designed to test your knowledge and sharpen your thinking.😎😎

✨ Think smart
✨ Diagnose wisely
✨ Compete confidently

🚨 Stay tuned… The first riddle is coming soon!

09/02/2026

A 63-years-old female suffers from pain upon eating specially spicy food.

Upon clinical examination, a 10-years-duration cauliflower lesion was detected on her cheek. Histopathological examination revealed 𝐏𝐚𝐩𝐢𝐥𝐥𝐚𝐫𝐲 𝐒𝐪𝐮𝐚𝐦𝐨𝐮𝐬 𝐜𝐞𝐥𝐥 𝐂𝐚𝐫𝐜𝐢𝐧𝐨𝐦𝐚.

Examine the attached photos to clearly define the essential features of PSCC, as well as to differentiate it from its differentials.

29/01/2026

28/01/2026

Case of the Day🤩🤩
11-year-old female patient presented with a large swelling in the lower right posterior jaw, first noticed 5 months earlier and showing rapid progression. The patient is medically free, with no relevant systemic conditions.
Clinical and radiographic evaluation revealed a large unilocular expansile radiolucent lesion, extending from the lower right lateral region to the first premolar. Needle aspiration yielded blood, followed by an excisional biopsy. Gross examination showed a solid mass related to impacted canine with multiple small cystic spaces on cut section.
Histopathological examination demonstrated numerous multinucleated giant cells within a fibrovascular connective tissue stroma, associated with chronic inflammatory cell infiltrate. Areas of aneurysmal change were identified as blood-filled pseudocystic spaces, with reactive bone trabeculae seen at the lesion periphery.
Based on these findings, the differential diagnosis included:Central giant cell granuloma, Brown tumor of hyperparathyroidism (excluded due to normal PTH levels), Cherubism (excluded based on clinical and radiographic presentation). Thus the final diagnosis: Central giant cell granuloma associated with secondary aneurysmal bone cyst

📌 this case is a great example of how histopathology, radiology, and clinical correlation come together for an accurate diagnosis😍😍

cell lesion
bone cyst

19/01/2026

Here we are AGAIN, with interesting case 🤩🤩
A 29-year-old female patient presented with a very large palatal swelling. The lesion was noticed from 8 months earlier with rapid growth, raising concern for an aggressive jaw pathology. The patient is undergoing regular renal dialysis and is on antihypertensive medication and heparin as part of the dialysis protocol.
Clinical and Radiographic examinations revealed a progressive expansile large radiolucent swelling of palate crossing midline, causing buccal and palatal bone resorption.
Needle aspiration yielded blood, then an excisional biopsy was subsequently performed to reach final diagnosis.
Histopathological examination revealed interconnected irregular trabeculae of osteoid tissue rimmed by plump osteoblasts (yellow arrows) embedded in a highly cellular fibrovascular connective tissue stroma. Pseudo cystic spaces surrounded by multinucleated giant cells were observed in some areas (green arrows).
Differential diagnosis was made as:
Central giant cell granuloma &brown tumor of hyperparathyroidism (no bone trabeculae, only giant cells collections),
fibrous dysplasia (ground glass appearance in x-ray),
ossifying fibroma usually associated with radiolucent rim surrounding lesion & may show different types of calcified tissues histologically).
Osteoblastoma associated with secondary aneurysmal bone cyst is our Final Diagnosis🧐🧐.

bone cyst
DON'T MISS ANY CASE
KEEP FOLLOWING😍😍

06/01/2026

A 13-year-old male patient presented with a unilateral swelling of the left posterior mandible. The lesion was first noticed two years earlier but recently undergo a rapid enlargement in the last five months, raising concern for an aggressive jaw pathology.
Clinical and Radiographic examinations revealed a progressive expansile, large multilocular swelling involving the left side of the mandible and extending from the lower left first molar region to the mandibular condyle. A Needle aspiration yielded blood, then an incisional biopsy was subsequently performed.
Histopathological examination revealed a dual pathological pattern: Pseudocystic spaces lacking epithelial lining, containing abundant red blood cells and surrounded by fibrocellular connective tissue rich in multinucleated giant cells, (consistent with an aneurysmal bone cyst–like component). Another areas showed odontogenic epithelium arranged in solid, macrocytic, microcystic, and acanthomatous follicles, each of them is composed of ameloblast-like peripheral cells with stellate reticulum–like central cells (diagnostic clues of follicular ameloblastoma).
FOLLICULAR AMELOBLASTOMA ASSOCIATED WITH ANEURYSMAL BONE CYST is our Final Diagnosis, which is considered as a rare hybrid Lesion in a Pediatric Patient.
Aneurysmal bone cyst is a benign, osteolytic lesion, which may arise secondarily in association with other neoplastic lesions, including some odontogenic Tumors as Ossifying Fibroma . Recognition of this rare association is crucial, as accurate diagnosis directly impacts appropriate surgical management and prognosis of such cases. tumors
DON'T MISS ANY CASE🤩🤩
KEEP FOLLOWING 😍😍

05/01/2026

Happy New Year🤩🥳
Interesting Cases about ABC are waiting you😍😍
DON'T MISS ANY & STAY TUNED🥰

02/01/2026

A Smart Start🤩🤩
Waiting to see you all😍😍