25/12/2023
General medical history:
• Wound since: 6 weeks.
• Severe obesity.
• Diabetes mellitus.
• Hypertension.
• Oedema of the legs (chronic).
• DEBRICHEM: 21 days to full granulation.
The patient entered the clinic with an infected lesion on the lateral side of the left leg. (Figure A)
the ulcer presented has been present for over six weeks. The wound initially started as a small post
traumatic lesion but started to become infected in a very short timeframe. Despite treatment with
silver and iodine containing dressings the ulcer was progressing. There was even no improvement
with antibiotic treatment.
DEBRICHEM application desiccated the exudative wound bed covered in slough. The slough was not
removed by DEBRICHEM or after application.(Figure B) One week after DEBRICHEM application the
wound bed shows a dark colour of the desiccated material on the wound bed. However, there are no
signs of (re-)infection present. (Figure C)
One week later at fourteen days post DEBRICHEM application, the crusts spontaneously detached
from the wound bed and granulation became visible. (Figure D) At the follow-up visit 21 days post
DEBRICHEM application full granulation was visible. (Figure E) from this stage, the wound progressed
to reepithelization and at day 50 the wound bed has decreased in size significantly.
