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اوراسكوب - OraScope

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اوراسكوب - OraScope

OraScope is a specialized lab in the diagnosis of Oral & Maxillofacial diseases.

اوراسكوب هو معمل متخصص في تشخيص أمراض الفم والوجه والفكين.

OraScope is an Oral and Maxillofacial Pathology Lab specializing in the diagnosis of diseases and conditions affecting the oral cavity, jaws, and related structures. Our team includes specialists with clinical and academic expertise, ensuring that each case is reviewed carefully and thoroughly. We aim to provide accurate and timely diagnostic reports to support treatment planning and patient care. Our Services Include:
• Biopsy examination and histopathological diagnosis
• Fine needle aspiration cytology (FNAC)
• Slide consultation and second opinions
• Histomorphometric image analysis and statistical interpretation for research purposes

أوراسكوب هو معمل أمراض الفم والوجه والفكين متخصص في تشخيص الأمراض والحالات التي تصيب الفم، والفكين، والهياكل المرتبطة بهما

يضم فريقنا مختصين ذوي خبرة اكلينيكية وأكاديمية، مما يضمن مراجعة كل حالة بعناية ودقة. نهدف إلى تقديم تقارير تشخيصية دقيقة وسريعه لدعم تخطيط العلاج ورعاية المرضى.

:تشمل خدماتنا
فحص الأنسجه والتشخيص النسيجي المرضي •
سحب الخلايا بالإبرة الدقيقة •
مراجعة الشرائح وتقديم الآراء الثانية •
التحليل الصوري الكمي للنسيج والتفسير الإحصائي للأبحاث•

30/07/2025

As promised, we’re continuing our discussion with a closer look at the histopathological features of our Proliferative Verrucous Leukoplakia (PVL) case.

(Missed the first part? Catch up here to follow the full case) https://www.facebook.com/share/p/18mbBpqwu9/?mibextid=wwXIfr

According to the WHO 2022 classification, grading dysplasia in papillary and verrucous lesions can be particularly challenging, as architectural abnormalities often predominate, while cytological atypia may be minimal or even absent.

In this case, the epithelium exhibited classic structural alterations consistent with a high risk lesion: papillary and verrucous surface architecture, basal cell clustering, irregular stratification, and reduced keratinocyte cohesion. Additional findings included keratin pearls within rete processes and expanded proliferative compartments, all of which reflect disordered epithelial maturation.

Despite limited cytological atypia, the extent and severity of the architectural alterations justified a diagnosis of moderate epithelial dysplasia in our evaluation, consistent with the WHO 2022 criteria.

Such patterns may represent early transformation and carry significant malignant potential, underscoring the importance of recognizing structure-led dysplasia in lesions like PVL.

26/07/2025

Tip #2
Biopsy ulcers from the margin, not the center!

The center of an ulcer often contains necrotic debris and inflammation, which are rarely diagnostic.

To capture the pathology, always sample the active margin, where abnormal tissue changes begin, ensuring you include both lesional and adjacent normal tissue.

لما تاخد عينة من قرحة في الفم، خدها من الحافة مش من المركز!

لأن مركز القرحة غالبًا بيكون فيه أنسجة ميتة والتهابات، وده نادرًا ما يفيد في التشخيص.

عشان توصل للتشخيص الصح، خُد العينة من الحافة, المكان اللي التغيرات النسيجية غير الطبيعية بتبدأ منه, وتأكد إن العينة تشمل جزء من الأنسجه المصابه والسليمه كمان.

23/07/2025

A case of mucoepidermoid carcinoma (MEC) in a 20-year-old female, presenting as an ulcerated lesion in the left posterolateral palate.

Initially misdiagnosed as a palatal abscess, the lesion underwent multiple incision and drainage attempts, but showed no clinical resolution. Due to its persistent non-healing nature, it was finally sent for histopathological examination.

Microscopy revealed classic features of MEC, including multiple cystic spaces, a mix of mucous, intermediate, and epidermoid cells, and the presence of clear cells.

This case is a reminder that clinical appearance can be misleading. We must keep reinforcing the importance of histopathology. Biopsy isn’t just for confirmation, it’s often the first and most crucial step to avoid delays in diagnosis and ensure timely, effective treatment.

20/07/2025

يسعدنا أن نعلن أن الدكتورة هديل قطط، عضو فريق أوراسكوب (بكالوريوس جراحة الأسنان، ماجستير ودكتوراه في أمراض الفم والوجه والفكين)، ستقدّم ندوة إلكترونية بعنوان:
“Oral Lesions: When to Suspect a Malignancy and How to Manage It”

📅 الجمعة، 25 يوليو 2025
⏰ الساعة 5 مساءً بتوقيت مصر | 7 مساءً بتوقيت باكستان
🎓 تسجيل مجاني + شهادة إلكترونية

ستتناول الدكتورة هديل استراتيجيات مهمة لتشخيص وتصنيف والتعامل مع الآفات الفموية، خاصة تلك التي قد تكون مرتبطة بأمراض جهازية.

ندعو جميع أطباء الأسنان والمهتمين إلى حضور هذه الجلسة العلمية المفيدة.

We’re pleased to share that Dr. Hadeel Kotat, member of the OraScope team (BDS, MS, PhD – Oral & Maxillofacial Pathology), will be delivering a webinar titled:
“Oral Lesions: When to Suspect a Malignancy and How to Manage It”

📅 Friday, 25th July 2025
⏰ 5 PM Egypt | 7 PM PKT Time
🎓 Free registration + E-Certificate

Dr. Hadeel will cover key strategies for identifying, classifying, and managing oral lesions, especially those with potential systemic significance.

We encourage dental professionals to attend and benefit from this focused discussion.

https://www.linkedin.com/posts/experience-dentistry-pk_experiencedentistry-dentistrywebinar-oralpathology-activity-7348396507940696064-MNzN?utm_source=share&utm_medium=member_ios&rcm=ACoAAD0RtaEB0MQMPqC7yvSoEEGVskh_Kj8tMxY

17/07/2025

يسرّنا في معمل أوراسكوب الإعلان عن نجاح تنظيم
محاضرة علمية مميزة لأطباء الأسنان بعنوان:

Oral Pathology Essentials: Early Detection & Biopsy Techniques

‎وذلك يوم الأربعاء 16 يوليو 2025، بقاعة التدريب في
مستشفى حلوان العام. قدّم فريق أوراسكوب المحاضرة، وتناول اللقاء أهمية الاشتباه المبكر في الأورام وتقنيات أخذ العينات وحفظها

‎ نتوجه بالشكر لإدارة المستشفى وكل من ساهم في إنجاح
هذا اللقاء العلمي، ونتطلع للمزيد من الفعاليات القادمة

We at OraScope Lab are pleased to announce the successful organization of an insightful scientific lecture for dentists titled:

Oral Pathology Essentials: Early Detection & Biopsy Techniques

Held on Wednesday, July 16, 2025, at the Training Hall of Helwan General Hospital.
The lecture was delivered by the OraScope team, and the session focused on the early suspicion of oral tumors and proper biopsy and specimen handling techniques.

Our sincere thanks to the hospital administration and to everyone who contributed to the success of this day. We look forward to more upcoming events.

16/07/2025

A typical case of complex odontome in a 17-year-old male was discovered incidentally during routine radiographic examination, revealing a radiopaque mass associated with an impacted lower left third molar. Surgical removal of the lesion, along with the impacted tooth, was performed.

Histopathological examination showed disorganized but mature dental tissues, including dentin, pulp tissue, cementum, and enamel spaces.

Complex odontomes are developmental hamartomas composed of dental tissues that lack anatomical resemblance to normal teeth.

Commonly occurring in the posterior mandible during adolescence, they can obstruct tooth eruption and should be surgically removed upon diagnosis to prevent potential complications.

Courtesy of Dr. Mohamed Gamal

12/07/2025

❌Myth: ”If a lesion looks like soft tissue only, no X-ray is needed.”

✅ Truth: Lesions on the gingiva or alveolar mucosa may arise from or extend into bone.

A simple periapical or panoramic X-ray can reveal hidden bone changes that affect diagnosis, biopsy planning, and treatment.

Don’t let appearances mislead you, always assess the bone before you biopsy.

الخرافة بتقول : لو شفت أي soft tissue lesion فمش لازم تعمل أشعه.

✅ الحقيقة: إن أي soft tissue lesion موجود في اللثة أو الalveolar mucosa ممكن يكون طالع من العضم أو داخل فيه.

ممكن ال periapical x-ray أو البانوراما تكشف عن تغيرات خفية في العضم وتؤثر على التشخيص وطريقة أخذ العينة وبالتالي العلاج المناسب.

ما تخليش شكل الlesion يضللك ، اطمن على العظم دايمًا قبل ما تاخد عينه.

09/07/2025

We present an interesting case of Central Giant Cell Granuloma (CGCG) in a 21-year-old female, involving the anterior maxilla, a location less commonly affected, as CGCG shows a strong predilection for the mandible, particularly in younger individuals. Radiographic imaging revealed a well-defined, expansile radiolucency crossing the midline.

Histology revealed classic features: fibrous stroma, scattered multinucleated giant cells, hemorrhage, and hemosiderin.

👉 A diagnostic tip we’d like to highlight, which pointed us toward CGCG, was the focal clustering of giant cells. This pattern, as opposed to diffuse distribution seen in other giant cell lesions, is quite characteristic and can be a valuable clue in histologic interpretation.

Of course, histology alone is not enough. Correlating with the clinical and radiographic context is critical, and systemic causes must be ruled out.

In our case, parathyroid hormone and calcium levels were assessed and found to be within normal limits, helping us confidently exclude brown tumor of hyperparathyroidism.

05/07/2025

Tip #1:
“If a lesion lasts more than 2 weeks, biopsy it.”

Many reactive oral lesions heal on their own or after removal of the cause. But if it’s persistent, it’s time for pathology, better to catch dysplasia or malignancy early.
Early detection is key. Don’t delay the diagnosis!

"لو فيه تغيّر نسيجي في الفم مستمر لأكثر من أسبوعين, لازم يتاخد منه عيّنة".

فيه كتير من التغيّرات النسيجية اللي بتظهر في الفم نتيجة عدوى أو إحتكاك مزمن بتختفي لوحدها أو بعد إزالة السبب.
لكن لو التغيّر فضل موجود، يبقى لازم نلجأ للفحص الباثولوجي علشان نلحق قبل ما يتحول لحاجة أخطر زي خلل في النسيج أو ورم خبيث.
الكشف المبكر بيفرق. متأجلش التشخيص!

02/07/2025

Here’s a fascinating example of bilateral epulis fissuratum, a reactive fibrous lesion of the oral mucosa caused by chronic irritation from ill-fitting dentures.

Histopathology revealed classic features of hyperplastic fibrous connective tissue covered by acanthotic stratified squamous epithelium.

But what truly caught our attention was the presence of Toto bodies, also called keratin pools. These are rounded, eosinophilic, keratin-like bodies found within the superficial epithelial layers.

First described by Toto in 1953, these structures are associated with chronic inflammation or irritation and are typically seen in lesions like epulis fissuratum, pyogenic granuloma, and inflammatory fibrous hyperplasia. Believed to result from keratin degeneration or altered keratinization due to chronic trauma, their presence indicates the longstanding nature of the lesion.

Have you come across Toto bodies in your practice? We'd love to hear your insights!

30/06/2025

Introducing: Oral Pathology Tips & Myths!🔬

At OraScope Lab, we believe early detection begins with awareness. Every now and then, we’ll be sharing quick, practical insights along with clarifying common misconceptions to help dental professionals recognize when to biopsy, avoid common pitfalls, and enhance clinical decision-making.

Let OraScope Lab be your trusted partner in delivering smarter, safer patient care.

25/06/2025

*** Myofibroma Showing its Classic Biphasic Morphology ***

A 6-year-old presented with a soft tissue swelling that caused looseness and eventual extraction of the lower left D. However, the lesion continued to grow after extraction.

Histology showed the classic biphasic (zonation) pattern of myofibroma; compact vascular balls/nodules (black circles) formed of fascicles of spindle cells (black arrows) encircling cellular zones of rounded cells (yellow arrows) rich in hemangiopericytoma-like, staghorn vessels (arrowheads). Areas showed concentric perivascular layering and occasional uneven myointimal proliferation (blue arrows).

Immunohistochemistry was performed to confirm the diagnosis and exclude key differentials. Alpha-SMA showed patchy positivity, while both STAT6 and beta-catenin were negative, ruling out solitary fibrous tumor and desmoid-type fibromatosis.

"It’s important to consider infantile myofibromatosis if multiple lesions or intrabony involvement are identified, especially in infants and very young children. Further imaging and systemic evaluation may be warranted in such cases."

Swipe through to see the striking features!

Courtesy of Dr. Mohamed El-Shammaa

Address

٥ ش عز الدين محمد عطيه - النزهه الجديده
Cairo

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Monday	1pm - 8pm
Tuesday	1pm - 8pm
Wednesday	1pm - 8pm
Thursday	1pm - 8pm
Saturday	1pm - 8pm
Sunday	1pm - 8pm

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