17/10/2023
Kill Verm
Result beyond expectations
Product properties
Composition
Each ml the product contains 1 mg Moxidectin
50. mg Triclabendazole.
Pharmacology:
Kill Verm Moxidectin is an endectocide active against a wide range of internal and external parasites and is a second generation of macrocyclic lactone of the milbemycin family. Its principal mode of action is interfering with neuromuscular transmission of the GABA (gamma amino butyric acid) – gated or glutamate-gated chloride channels.
Kill Verm Moxidectin stimulates the release of GABA and increases its binding to the postsynaptic receptors, and binds to the glutamate-gated chloride channels. The net effect is to open the chloride channels on the postsynaptic junction to allow the inflow of chloride ions and induce and irreversible resting state.
This result in flaccid paralysis and eventual death of parasites exposed to the drug.
Kill Verm Triclabendazole is a flukicide belonging to the benzimidazole group of anthelmintics. It is well established that benzimidazole anthelmintics selectively bind to ß-tubulin, thus causing the depolymerisation of microtubules and the subsequent disruption of microtubule – based processes in helminthes.
Kill Verm Moxidectin is distributed throughout the body tissues but due to its lipophilicity the highest drug concentrations are obtained in fat tissue.
Kill Verm Moxidectin undergoes biotransformation by hydroxylation.
The majority of the oral dose of triclabendazole in sheep, goats and rabbits is eliminated in faeces after 6-10 days, as unchanged drug or products of biliary excretion. Urinary excretion is minimal.
Indications of use
For the treatment of mixed nematode and fluke infections, caused by moxidectin and triclabendazole sensitive strains of:
Kill Verm
Moxidectin+Triclabendazole
- type: anti parasites
- usage: Oral Solution
- Packaging: 1 L
Storage conditions
Keep the product below 25 °C and avoid from direct sunlight.
Do not freeze.
Withdrawal Time
Meat: 31 days
Milk: not authorized for milks that consumed for use in human consumptions. This includes the dry periods.
Recommendations:
This product is safe for use in breeding animals.
Avoid direct contact with skin.
Do not smoke, drink or eat when suing this product.
Wear impermeable rubber gloves during use.
Wash hands after use.
infection. All animals in a group should be treated.
Shelf-life after first opening the immediate package in.
All medication and this product should be kept out of the reach of children
