Fundación MEDINA

26/08/2025

🚨 New paper out in the Journal of Natural Products!
In collaboration with the University of Granada through the Micro-Lichens project, we report the discovery of new glycinocins (E-H) lipopeptides with calcium-dependent antibiotic activity.

Interestingly, standard Marfey’s analysis couldn’t resolve the absolute configuration of all amino acids. By combining biosynthetic gene cluster (BGC) analysis with Marfey’s at lower temperature, we successfully determined their stereochemistry.
https://pubs.acs.org/doi/10.1021/acs.jnatprod.5c00740
Fundación MEDINA Universidad de Granada Junta de Andalucía

In an antifungal screening of extracts from microbial strains isolated from gypsum outcrops in Granada, Spain, four new cyclic lipopeptides, glycinocins E–H (1–4), were identified from Streptomyces sp. CA-297274 and exhibited potent activity against Zymoseptoria tritici, the causal agent of sept...

26/08/2025

🚀 Excited to share our latest work drug discovery:

MEDINA has developed an innovative high-throughput screening platform using NanoBRET technology ( Corporation ) to profile bioactive compounds, using the European Chemical Biology Library as a PoC.

✨ The results provide new insights into the development of NLRP3 inhibitors as potential therapeutic agents for inflammatory diseases.
This work underscores how combining advanced screening technologies with diverse chemical libraries can open new avenues for drug discovery.

https://www.sciencedirect.com/science/article/pii/S2472555225000516

EU Openscreen Universidad de Granada Junta de Andalucía

21/07/2025

Fundación MEDINA en el XIX Congreso de la Sociedad Española de Biotecnología 🧬

Ha sido un placer poder participar de la mano de

Victor Gonzalez-Menendez, Investigador Senior del Área de Microbiología y miembro del comité científico de BIOTEC 2025, que ha sido responsable de la coordinación de la sección de Biotecnología Mircrobiana.

Y Gioele Pecin, investigador pre-doctoral en la Fundación MEDINA, quien presentó los avances de su investigación enmarcada en la red doctoral europea MAGic-MOLFUN con la comunicación oral “OSMAC and Metabolomic Engineering Strategies to Improve the Chemical Information of Stanjemonium spectabile and Enhance the Production of a Novel Compound" centrada en el descubrimiento de un nuevo compuesto fúngico con potente actividad citotóxica.

Más info 👉 https://bit.ly/4kU43dM
SEBiot - Sociedad Española de Biotecnología Marie Skłodowska-Curie Actions Universidad de Granada Junta de Andalucía

03/07/2025

🥳 🎉 🎊 Fundación MEDINA celebrates its 15th anniversary with the launch of its new corporate video, an in-depth look at its work as an international reference center in the discovery of new drugs from natural products.

📽️ The video highlights the work of its main research areas and offers a visual tour of the facilities, platforms, and equipment that make up Fundación MEDINA.

In this special year, alongside the release of the corporate video, Fundación MEDINA has prepared a commemorative program of activities and unveiled a refreshed visual identity.

👀 We invite you to watch the video, share it, and continue being part of this celebration.
https://youtu.be/oONVurXWSlI?feature=shared
http://bit.ly/44wnAuz
Universidad de Granada Junta de Andalucía

26/06/2025

¡Un placer haber participado en la celebración del ! 🎉
Diego Pozas, Gerente de Fundación MEDINA, participó en la mesa redonda "Alianzas estratégicas para impulsar la investigación e innovación biomédica en Granada Salud".
Durante la mesa redonda, Diego resaltó el singular modelo público-privado de Fundación MEDINA, que combina la excelencia científica y la búsqueda de financiación competitiva con un fuerte enfoque de mercado, conectando eficazmente con la industria y las instituciones académicas.
https://bit.ly/4ejOUAC
Instituto de Investigación Biosanitaria de Granada - ibs.GRANADA Escuela Andaluza de Salud Pública - EASP Granada Salud FIBAO Universidad de Granada Junta de Andalucía

25/06/2025

We're excited to be attending in !
Dn, Senior Researcher at FFundación MEDINA has presented her poster about the molecular characterisation of the Tuberculosis vaccine using its exometabolome. It's always inspiring to connect with colleagues, explore innovative research, and be part of the vibrant metabolomics community.
UUniversidad de ZaragozaUUniversidad de GranadaMSD España JJunta de Andalucía

25/06/2025

Last week Olga Genilloud, Daniel Oves-Costales, and Marina Sánchez Hidalgo from Fundación MEDINA attended the 20th International Symposium on the Biology of Actinomycetes ( ) in Egmond aan Zee, Netherlands.
Congratulations to Daniel Oves Costales for his oral presentation on some of the strategies that we are employing at MEDINA to discover new antibacterial compounds and to Marina Sánchez-Hidalgo for showcasing in two posters new research data on our medinamycin and kibdelomycin.
Many thanks to the organizers and to everyone who contributed to the great science, fantastic presentations, and excellent posters.
Universidad de Granada MSD España Junta de Andalucía

23/06/2025

Fundación MEDINA attended , the international biennial scientific conference on marine biotechnology, held on June 17–18 at UiT Norges arktiske universitet, .
Georgia Karyofyllidou, PhD Student at Fundación MEDINA, within the project for marine biodiscovery presented her poster explaining the Isolation and structural elucidation of new compounds from the marine-derived fungus Pyrenochaetopsis indica.
Universidad de Granada MSD_España Junta de Andalucía

23/06/2025

Fundación MEDINA ha asistido al ### Congreso Nacional de Microbiología , celebrado en Jaén.
Nuestra compañera Rachel Serrano Bacallao, del Área de Microbiología, presentó su comunicación oral en la sesión del grupo especializado Microbiología Industrial y Biotecnología Microbiana: "Nueva diversidad química en hongos para el descubrimiento de nuevos agentes fungicidas".
https://congresosem.es/SEM2025
Sociedad Española de Microbiología Universidad de Granada MSD_España Junta de Andalucía

18/06/2025

Thrilled to share that Rosario Fernandez Godino, Head of Screening and Target Validation at Fundación MEDINA, has presented m3DinAI at !
This innovative platform, developed entirely in , leverages AI and 3D tumor spheroid models for high-throughput screening. It automates the analysis and quantification of phenotypic changes in high-content images, drastically improving the speed and accuracy of compound screening accelerating the identification of promising drug candidates.
https://convention.bio.org/speaker/rosario-fernandezgodino

I am Biotech Universidad de Granada MSD_España Junta de Andalucía

16/06/2025

📢 Reminder! 📢
Don't forget to mark your calendars! The next MEDINA Seminar Series is happening next week.
We are excited to host Dr. Bradley Moore, Distinguished Professor of Marine Chemical Biology and Director of the Center for Marine Biotechnology and Biomedicine at Scripps Institution of Oceanography, University of California, San Diego.
Dr. Moore will be presenting a talk on:
“Understanding and Translating the Specialized Chemistry of the Ocean’s Living Wonders”.

🗓️ Date: June 24th
🕛 Time: 12:00 – 13:00 (followed by networking refreshments)
📍 Location: attend in person at the Conference Hall at Fundación MEDINA, Fundación PTS - Parque Tecnológico de la Salud, Granada or
💻 Online: Via Zoom 👉 registration required https://bit.ly/4j8kMZW

Don’t miss this fantastic opportunity to engage with Dr. Bradley Moore, learn more about chemical, biochemical and genetic approaches to understanding and bioengineering the biosynthesis of natural products drugs and toxins and connect with Granada’s vibrant scientific community.
Universidad de Granada MSD España Junta de Andalucía Scripps Institution of Oceanography