
30/04/2025
DOES TRT MAKE A MAN INFERTILE?
Thinking about starting Testosterone Replacement Therapy? There is one important thing to consider: exogenous testosterone injections reduce your fertility.
For men who want to increase their testosterone level, but don´t want to abandon the idea of having (more) children, there is an alternative option: increase your own natural testosterone production.
HOW DOES IT WORK AND WHY IS THE OUTCOME DIFFERENT:
The body´s mechanism of testosterone production is controlled by receptors in the body that inform the brain how much hormones are circulating. When there is a high level of hormones circulating in your blood, the receptors send signals to the hypothalamus and the pituitary gland stops liberating LH (Luteinizing Hormone) and FSH (Follicle stimulating hormone) into the bloodstream.
The go**ds (te**es) have receptors for LH and FSH. They need LH to stimulate the production of testosterone and FSH to stimulate the production of s***m.
With TRT you are directly injecting testosterone, which the receptors in your body detect and send signals to the brain to stop releasing LH and FSH in the bloodstream. Without these, the go**ds stop their production of testosterone and s***m. The testosterone from the injection improves s*xual function, but the go**ds remain inactive. Semen with little or no s***m leaves the man infertile.
The alternative treatment consists of an oral supplementation with a compound that attaches to the hormone receptors in your body and blocks them from sending signals to the brain. The pituitary gland does not receive the information that there are enough hormones in the blood. Therefore, it will start releasing more LH and FSH that stimulate the go**ds to produce more Testosterone and more s***m. Result: higher level of testosterone and better quality of semen with increased fertility.
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