22/09/2025
Frozen vs. Fresh embryos: which is safer for avoiding high-risk twin pregnancies? A major study has answers that could change IVF practices
🔬 A multicenter study published in Reproductive BioMedicine Online indicates that Frozen Embryo Transfer (FET) significantly lowers the incidence of monozygotic twinning (MZT) compared to fresh embryo transfers. 📉
The study reports a MZT rate of 2.25% in FET cycles compared to 3.10% in fresh cycles, underscoring the potential advantages of FET for improving safety in fertility treatments, particularly for patients at an increased risk of complications.
This research highlights the necessity for continued investigations into how laboratory procedures influence embryonic development. 🌱 Let us advocate for safer and more effective Assisted Reproductive Technology (ART) practices!
Chen, N., Chen, R., Chen, S., Li, R., Mo, M., & Yang, D. (2023). Risk factors associated with monozygotic twinning in offspring conceived after single embryo transfer: a retrospective cohort study of 15 567 pregnancies. Human Reproduction Open, 2023(4), hoad035. https://doi.org/10.1093/hropen/hoad035