09/12/2022
30 years of electrophysiological recordings during classical eyeblink conditioning are summarized in this review. A wide perspective of different brain sites involved in this ‘rather’ simple learning task. We describes the firing activities of motor cortex, red and interpositus nuclei, medial prefrontal cortex, hippocampus, claustrum, brainstem motoneurons and eyelid muscles during eyeblink conditioning. Pure physiology!
For almost a century the classical conditioning of nictitating membrane/eyelid responses has been used as an excellent and feasible experimental model to study how the brain organizes the acquisition, storage, and retrieval of new motor abilities in alert behaving mammals, including humans. Lesional...