Adama Public Health Research and Referral Laboratory center

18/11/2025

central dogma of molecular Biology

17/11/2025

Health Tips:-
How do scientists copy DNA millions of times from just a tiny drop of sample?
If you’ve ever wondered how COVID tests worked, how forensic labs identify criminals, or how genetic diseases are detected, the answer is PCR.

PCR is basically a DNA photocopier.
You take a small piece of DNA, give it the right ingredients, and the machine multiplies it again and again until there’s enough to study.

What’s wild is that the entire process runs on:
primers, nucleotides, an enzyme stolen from a heat-loving bacterium, and a machine that just keeps heating and cooling your sample like a biological thermostat.

Denature.
Anneal.
Extend.
Repeat 30–40 times.
Boom, millions of DNA copies.

Whether it’s diagnosing a virus, solving a crime, cloning a gene, or doing cutting-edge research, PCR is the backbone of modern molecular biology.
Understand this…and half of biotechnology starts making sense.

15/11/2025

14/11/2025

Hemorrhagic Fevers | overview for community education and prevention

Eight suspected cases of hemorrhagic fever have been reported in Jinka town, Ethiopia. The exact virus is still under laboratory investigation, but health authorities have intensified surveillance, contact tracing, and community awareness to prevent further spread.

As prevention is paramount, I took time to compile a detailed overview for community education and prevention in the affected area and beyond.

🧾 Definition

• Viral Hemorrhagic Fevers (VHFs) are a group of severe illnesses caused by several families of viruses.

These infections are multi-systemic, disrupting vascular integrity, immune responses, and the function of vital organs.

Clinically, they are marked by high fever, a tendency to bleed due to vascular and coagulation abnormalities, and progressive multi-organ dysfunction, often leading to life-threatening complications1,2.

🩺 Clinical Presentation

• Early symptoms: sudden fever, fatigue, muscle aches, headache, sore throat.

• Progressive symptoms: abdominal pain, vomiting, diarrhea, rash.

• Severe signs: bleeding (nose, gums, gastrointestinal), low blood pressure, shock, organ failure.

• Note: Bleeding is not always present, but vascular damage is a hallmark1.

🔬 Diagnosis
• Clinical suspicion: based on symptoms, outbreak context, and exposure history.
• Laboratory tests (confirmation):
o PCR for viral RNA
o ELISA for viral antigens/antibodies
o Blood counts (low platelets, leukopenia)
o Liver and kidney function tests

• Differential diagnosis: always do not forget the common problems in the setting including malaria, typhoid, sepsis, dengue1.

🧪 Investigations
• Complete blood count: may show thrombocytopenia, leukopenia.
• Coagulation profile: prolonged clotting times.
• Biochemistry: elevated liver enzymes, renal impairment.
• Imaging: rarely needed, but may show organ involvement.

💊 Case Management:
• Supportive

13/11/2025

ከጤና ሚኒስቴር እና ከኢትዮጵያ የሕብረተሰብ ጤና ኢንስቲትዩት በወቅታዊ የጤና ጉዳይ የተሰጠ መግለጫ

29/10/2025

Adama public health research and referral laboratory center is accredited by the Ethiopian Accreditation services (EAS) to perform tests in accordance with the attached scope of accreditation in the field of MEDICAL TESTING.
APHRRLC is accredited in accordance with the requirements of ISO15189:2022, medical laboratory Requirements for quality and competence. The accreditation demonstrates technical competence with the defined scope and the operation of a laboratory quality management system. While this certificate remains valid, Adama PHRRLC authorized to use the combined ILAC-EAS accreditation mark/symbol to issue test report and/or certificates.
Hence APHRRLC is accredited by six scopes such as TB microscopy test, TB Gene Xpert test, TB Culture test, Molecular Viral load tests and molecular EID tests),Bacteriology (with 8 samples examination).
Congratulations 🙏

11/09/2025

Dear All,

On behalf of APHRRLC, I would
like to extend our warmest wishes to you and your team on the occasion of the Ethiopian New Year! As you celebrate this joyful time of renewal and hope, may the coming year bring you prosperity, success, and happiness both personally and professionally.

We truly value our partnership and looking forward for the opportunity to work with you. It is our sincere hope that our collaboration continues to grow and thrive in the year ahead.

Happy Ethiopian New Year! May this new year be filled with blessings and achievements for you all.

Best regards,
Mesfin Bekele Tolosa