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  in combinationGulvas Met 50mg/1000mg Tablet Vildagliptin + Metformin Hydrochloride  Patients with type 2 diabetes mell...
01/09/2023

in combination

Gulvas Met 50mg/1000mg Tablet


Vildagliptin + Metformin Hydrochloride


Patients with type 2 diabetes mellitus who are not adequately controlled on Metformin Hydrochloride or Vildagliptin alone, or who are already treated with the combination of Vildagliptin and Metformin Hydrochloride as separate tablets, should take this tablet as an adjunct to diet and exercise to improve glycaemic control.


Vildagliptin works by inhibiting DPP-4 (Dipeptidyl peptidase-4), an enzyme that breaks down the incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucagon-like peptide-2) (glucose-dependent insulinotropic polypeptide). Vildagliptin inhibits DPP-4 activity quickly and completely, resulting in higher endogenous levels in the fasting and postprandial states.

&
This combination may be started twice daily, with one tablet in the morning and the other in the evening, depending on the patient's current Metformin dose. Patients who are currently taking Vildagliptin and Metformin as separate tablets may be switched to this combination, which contains the same doses of both drugs. Vildagliptin doses greater than 100 mg are not recommended.


When Vildagliptin (100 mg once daily) was combined with Metformin Hydrochloride, no clinically significant pharmacokinetic interaction was observed (1,000 mg once daily). Drug interactions are unlikely with Vildagliptin. Vildagliptin is unlikely to interact with co-medications because it is not a cytochrome P (CYP) 450 enzyme substrate, nor does it inhibit or induce CYP 450 enzymes.


Patients who have a known hypersensitivity to Vildagliptin, Metformin Hydrochloride, or any of the excipients should avoid this combination. It's not recommended for people who have kidney disease or dysfunction, a heart attack, or septicaemia.


Headache, tremor, dizziness, nausea, hypoglycemia, and other side effects are the most common.


&
Because there are no adequate and well-controlled studies in pregnant women, this combination should not be used during pregnancy unless the potential benefit outweighs the risk to the fetus. There have been no studies done on the components of this combination. Because Vildagliptin and/or Metformin Hydrochloride are unknown.



&
Metformin accumulation can cause lactic acidosis. If metabolic acidosis is suspected, treatment should be stopped immediately and the patient admitted to the hospital. Patients with normal renal function should have their serum creatinine levels checked at least once a year, and patients with serum creatinine levels above the upper limit of normal and elderly patients should have their serum creatinine levels checked 2–4 times a year.

Therapeutic Class
Oral hypoglycemic preparations in combination

Storage Conditions
Keep away from light and heat in a dry place. Keep out of children's reach.

Pharmaceutical Name
Novartis (Bangladesh) Ltd.

Alternative brands for
Galvus Met 50/850

31/08/2023

ክቡር ጠቅላይ ሚኒስተር ዶ/ር አብይ አህመድ የትምህርት ሚኒስቴር ሚኒስትር ፕሮፌሰር ብርሃኑ ነጋን የአዲስ አበባ ዩኒቨርሲቲ ቻንስለር አድርገው ሾሙ፡፡

ነሓሴ 25/2015 ዓ.ም (የትምህርት ሚኒስቴር) የትምህርት ሚንስትሩ ክቡር ፕ/ር ብርሃኑ ነጋ በቅርቡ የመጀመሪያው ራስ ገዝ ዩኒቨርስቲ እንዲሆን በሚንስትሮች ምክር ቤት የተወሰነው የአዲስ አበባ ዩኒቨርሲቲ ቻንስለር በመሆን ተሹመዋል፡፡

ክቡር ጠቅላይ ሚኒስተር ዶ/ር አብይ አህመድ ሹመቱን የሰጡት የአዲስ አበባ ዩኒቨርሲቲ የመጀመሪያው ራስ ገዝ ዩኒቨርስቲ ሆኖ እንዲቋቋም በ1294/23 የራስ ገዝ አዋጅ በረቀቀው መሰረትና የሚኒስትሮች ምክር ቤት ሃምሌ/28/2015 ዓ.ም ባካሄደው 23ኛው መደበኛ ስብሰባ የዩኒቨርሲቲዎችን የራስ ገዝ ማቋቋሚያ ደንብ ላይ ተወያይቶ ማጽደቁን ተከትሎ ነው፡፡

በመሆኑም የከፍተኛ ትምህርት ተቋማት የአካዳሚክ ነጻነት እንዲረጋገጥ፣ከፖለቲካዊም ሆነ አስተዳደራዊ ጣልቃ ገብነት ነጻ ሆነው የመማር ማስተማር እና የምርምር ሥራዎችን በላቀ መልኩ እንዲፈጽሙ እንዲሁም የሰው ሀብትና የፋይናንስ አስተዳደር ነጻነትን በማረጋገጥ በሀገሪቱ የማህበራዊና ኢኮኖሚያዊ እድገት ላይ የላቀ አስተዋጾ እንዲያበረክቱ ለማስቻል ነው፡፡

አዲስ አበባ ዩኒቨርሲቲ ራስ ገዝ ዩኒቨርሲቲ መሆኑን ተከትሎ ከተሾሙት ቻንስለር በተጨማሪም አዲስ የቦርድ አመራሮች የተሰየሙለት ሲሆን ቦርዱም ዩኒቨርሲቲውን በሃላፊነት ሊመሩ የሚችሉ ፕሬዚዳንት እና ም/ፕሬዚዳንቶችን በቀጣይነት ይሾማል።

ለተጨማሪ መረጃ
• እሴተ የሺጥላ ከፍተኛ የኮሙኒኬሽን አማካሪ
ስልክ - 0911235322
ኢ-ሜል- esete.yesh*tla@ethernet.edu.et
• አመለወርቅ ህዝቅኤል የህዝብ ግንኙነትና ኮሙኒኬሽን ስራ አስፈጻሚ
ስልክ - 0911976196
ኢ-ሜል- ameleworkhizkeal@ethernet.edu.

30/08/2023

JJU S.H.Yabare Comprehensive Specialized Hospital
Dr.Hassen Mohamed Areys ( OBGYN Senior, Assistant Professor)

❤️❤️❤️🌟🌟🌟
28/08/2023

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28/08/2023

5 Differences Between Stress And Anxiety

By Chris Butler
Published on June 26, 2016
Last modified June 11, 2023
ANXIETY, MENTAL HEALTH

Stress and anxiety are similar. People often use these two words interchangeably, but there is a difference between these two emotional responses. It’s time to eliminate the confusion. Here are five differences between stress and anxiety.

What is stress?

Stress is a normal emotional response to a demand put on your brain or body. When you experience a challenge at work or school or have a significant life change, you will feel stressed. Some people cope better with stress than others. Stress can affect your health, so you must pay attention to the cause and reduce it. Examples of stress include:

Stressors related to school, work, or your family. Stress from a sudden negative experience or change such as a divorce, death in the family, losing your job, or illness.
Stress from an event such as an assault, war, major accident, or natural disasters like a hurricane, tornado, or earthquake. This type of traumatic event can produce physical symptoms and temporary emotional ones.

What is anxiety?
They describe anxiety as a natural response to stress. It involves feeling fearful or apprehensive about the future. You may feel anxious on your first day at work or when you have a job interview. Anxiety causes these emotional reactions:

Worry
Nervousness
Concern
Uneasiness
If your anxiety continues longer than six months and interferes with your life, you could have an anxiety disorder. Anxiety disorders make you feel fearful all the time. Sometimes these fears are intense or debilitating. Everyday things can become difficult for you because of your constant worry about what could happen. Left untreated, your condition may get worse.

What are anxiety disorders?

Anxiety disorders are a widespread type of emotional disorder. They affect people of all ages. Common anxiety disorders include the following:

Panic disorder
Phobias
Social anxiety disorder
Obsessive-compulsive disorder
Separation anxiety disorder
Illness anxiety disorder
Post-traumatic stress disorder

Who’s most at risk for an anxiety disorder?

Researchers suggest there are genetic and environmental factors that can contribute to who develops an anxiety disorder.

General risk factors include the following:

Individuals who are especially shy or had inhibitions as a child
Exposure to a stressful or negative experience in early childhood or early adulthood.
Biological relatives who have a mental illness or other mental health issues
Physical conditions like thyroid problems, heart problems, or certain medications can cause anxiety disorders

differences between stress and anxiety

It may be hard to decide if you’re struggling with stress or anxiety. But there are noticeable differences between the two of them.
Here are the five significant differences between stress and anxiety.

1 – Different in how long they last
Stress is a reaction to an external cause. It could be a test at school or your first day at work. Usually, your feelings of stress go away once you finish the test or complete your first day of work. Anxiety reacts to an external, but it doesn’t go away when you remove the stressor.

2 – Different in how they affect your body
If your conditionspersists, it can get so severe that it turns into an anxiety disorder. Anxiety can affect your body in a variety of ways, including

Having trouble concentrating
Your mind goes blank
Fatigued all the time
Muscle tension
Can’t control your worry
Sleep problems
Unsatisfying sleep
Stress is a physical or emotional response to the demands and pressures of your life. Some people don’t process stress well, resulting in health problems such as the following:

Digestive disorders
Headaches
Sleep disorders
Heart problems
Asthma
Overeating
Alzheimer’s disease

3 – Stress has a known cause, but anxiety may not have a noticeable trigger
You usually know what makes you feel stressed out. You know your job is a source of stress for you. But it may be hard to pin down where your triggers originated. You may not remember an unpleasant childhood experience or not know that you have a genetic tendency toward a specific mental health disorder. That’s why it’s essential to see a professional counselor who can help you find the cause of your anxiety.stressed loved oneSave

4 – Stress is manageable, but anxiety may not be. Most of the time, when you have stress, you can figure out how to manage it or get rid of it. Long-term anxiety can become unmanageable, so that you can’t do your regular daily tasks.

5 – Different emotional responses
Anxiety and stress cause different physical and emotional reactions. Here are some differences and similarities between the two emotional responses.

Anxiety
Stress
Both
restless
moodiness
racing heartbeat
nervous
anger or irritability
fast breathing
tense
dizziness
diarrhea
sweating
unhappiness
constipation
feeling of dread
overwhelmed
higher blood pressure
uneasy
loneliness
fight or flight response

Primary causes of stress
There is a wide assortment of reasons for feeling stressed. These include the following triggers:

Unhappy at work
Too much responsibility at work
Working too long of hours
Unclear expectations of you at work
Dangerous work
Lack of security at work
worried about being fired
Death of a loved one
Divorce
Financial problems
Getting married
Moving
Illness
Emotional problems
Caregiving of elderly or sick family member

Causes of anxiety
Anxiety is part of your life, but after several months, if you’re still experiencing intense fear about everyday situations, you could have an anxiety disorder. Anxiety symptoms can start in childhood or teen years and can continue into your adulthood.

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Causes of anxiety disorders
Stress from illness: Serious health conditions cause you to worry or worry about your treatment.
Trauma: If you experienced abuse or witnessed a traumatic event as a child, you’ll be at risk of an anxiety disorder.
Stress buildup: A big event or smaller stressful life situations can trigger your anxiety. If there was a death in your family, plus work stress plus financial problems-these can pile up on you. You may end up with extreme pressure.
Personality: Some personality types are more apt to experience this than others.
Drugs and alcohol: Misuse of drugs and alcohol and withdrawal can make your anxiety worse.
Having family members with mental illness: Anxiety disorders run in families.
How to manage problems of stress and anxiety
Anxiety and stress are normal reactions to difficult situations in your life. They provide the fight-or-flight response that keeps you safe if you’re in danger. Generally, stress is your body’s reaction to a threat. But this outcome is your body’s reaction to stress. You need to figure out what stressors are setting off your anxiety and stress. Then you can better deal with them. Here are some things to help you manage them.

Exercise
According to studies, regular exercise has a positive impact and heals your mind. Some activities that can help you with your stress or anxiety include:

Running
Biking
Tennis
Dancing
Swimming
Fast walking
Talking
Seek counseling for your anxiety
Talking with a trusted friend, your pastor, or a family member is essential to help you reduce overthinking. Talking about your worries, fears, and stressors can help relieve them.

Save
Setting boundaries
Set boundaries for yourself on what you will take on at work, home, or school. Know what causes your stress or anxiety, and eliminate it from your life. Of course, not everything can be taken away, but there are many things you can do to find relief. Perhaps it’s time to find remote work instead of staying at a job where you need to commute to work. Maybe you need to pull out of some of your responsibilities at church or school.

Setting boundaries is just one positive management tool for reclaiming your mental health.

Relaxation
Relaxation techniques are another way to improve your mental health. Try some of these techniques:

Deep breathing exercises
Visualizing a tranquil scene or the beach
Practice yoga
Practicing Ta Chi
Slowly counting to 10
When do you need to see a doctor?
If you find you can’t deal with your mental illness, it could be time to see a doctor. Warning signs you need to see a doctor include things like
Excessive worry makes it hard for you to do your everyday daily life
Irrational fears
Significant changes to your sleep patterns
Important changes to your hygiene habits
Feeling moody and low
Thinking about self-harm
Other things you can do to deal with your stress and anxiety include these:
Accept the stuff you can’t control
Figure out what triggers your reaction
Limit your caffeine and alcohol
Settle to be good, but don’t aim for perfection
Eat nutritious foods
Get enough sleep
anxiety disordersSave
Final thoughts of beating stress and anxiety
Some stress and anxiety are typical in your life. You may have a hard time distinguishing the difference between stress and anxiety since they are similar. Stress typically has limits, and stressors cause it. Once the causes of stress are removed, your stress will go away. The reasons for anxiety are harder to nail down. Plus, if it continues, you may end up with an anxiety disorder. Fortunately, you can manage and improve your mental health by setting boundaries, exercising, and relaxation techniques. If none of this helps, or if your symptoms get worse, it could be time for you to speak to a doctor to get relief.

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Author: Chris Butler

About the Author

Chris Butler
Chris is a happy dad and co-creator here at PoP. Since 2009, Chris has experienced multiple life changing positive events, released over 100 pounds, attained inner peace, created academic and professional success, and learned to see increased abundance in every area of life, while remaining grateful and joyous through the journey. Chris has transformed from rock bottom in the areas of personal health, fitness, and spirituality. He credits it all to the power of positive thoughts, words, actions and reactions.

In his spare time, Chris enjoys music, fitness, plant-based nutrition and inspiring others to take positive action steps and catch their own dreams in life. Chris also loves to spend quality time with his lovely wife Kristen and two beautiful daughters.

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