Institut des Maladies Neurodégénératives Bordeaux

29/01/2026

🎙️ Podcast : l'IA pour comprendre l'apprentissage humain - avec Chloé Mercier, chercheuse à l'IMN.

💡Dans le cadre de sa thèse, elle s’est appuyée sur l’IA pour décrypter comment l’humain apprend et développe sa créativité via l’observation d’une activité CréaCube. Son observation et son analyse permet de mieux comprendre les processus créatifs.
❓Elle s’intéresse désormais à comprendre s’il est possible d’utiliser l’IA générative dans un processus d’apprentissage sans tuer l’envie d’apprendre et en cherchant à s’améliorer ?

🎧

Serge Abiteboul nous emmène une nouvelle fois à la rencontre d’une doctorante et de sa thèse. Cette semaine il s’agit de Chloé Mercier, jeune docteure, qui cond

26/01/2026

Light, a non-invasive alternative to painkillers 💡🧠

Turn on the light to turn off the pain: this is the principle behind a new pain relief method called LIA (Light-Induced Analgesia), discovered in rodents by Benjamin Sueur, Pascal Fossat, Eric Boué-Grabot and al.

👉 CNRS press release : https://www.cnrs.fr/en/node/12632
👉 Nature Communications article : https://www.nature.com/articles/s41467-025-67819-w

Membrane ion channels can be responsive to a variety of stimuli such as pressure, temperature, or pH. Here, the authors show that simply shining 365 nm light activates a native potassium channel in rodent pain-sensing neurons, delivering powerful analgesia without drugs or genetic manipulations.

21/01/2026

SATT Aquitaine has decided to invest €317,890 (including €40,000 in intellectual property) in the development of the NOVEL project, help by Benjamin Dehay, Sébastien Lecommandoux and Philippe Barthélémy.

📍For more :

La SATT Aquitaine investit 317 890 € dans le projet NOVEL, visant à développer un traitement innovant pour ralentir la progression de la maladie de Parkinson et l’atrophie multisystématisée.

19/01/2026

🧠 IMPACT Research Network's Science Day :
2 post-doctoral researchers from the lab had the opportunity to present their work :
🔸Elise Cosenza : Development of Diffusion MRI and tractography of white matter fibres in small animals at 7 Tesla
🔸Anna Matsulevits : Relevance of Disconnectome Approaches for Prognostication following Ischemic Cerebral Infarct

👉 Find out more about their research project opposite: https://www.canal-u.tv/chaines/univ-bordeaux/journee-scientifique-du-reseaux-recherche-impulsion-impact

Université de Bordeaux| Bordeaux Neurocampus

Réseau Recherche Impulsion IMPACT / Journée scientifique, 11 décembre 2025, Université de Bordeaux

18/12/2025

L'ensemble de l'IMN a pu se retrouver autour d'un joli repas de Noël et vous souhaite d'excellentes fêtes de fin d'année ! 🎄🎅

📸 Arnaud Rodriguez

15/12/2025

📰 "Targeting pain with deep brain stimulation: Insights into the thalamus and associated structures", published in Deep Brain Stimulation

✒️ Rabia Bouali-Benazzouz, Pascal Fossat, Abdelhamid Benazzouz

📍 For more :

15/12/2025

📰 "Alzheimer’s Tau seeds-induced pathology enhances hippocampal extracellular diffusion", published in communications biology.

✒️ J. Estaún Panzano, A. Lovisotto, C. Mazzocco, C.Piva, M. Darricau, V.Planche, B. Dehay, E. Bezard and al.

📍 For more :

Quantum dot single-particle tracking in live mouse brain tissue was used to study extracellular diffusion in a Tau model. Tau aggregation and inflammation increase extracellular diffusion which may facilitate tau pathology propagation.

12/12/2025

New article about how the basal ganglia and cortex work together to learn and adapt complex movements ! 🧠⚙️

📰 "Reward-driven adaptation of movements requires strong recurrent basal ganglia–cortical loops", published in PNAS
✒️ Arthur Leblois, Thomas Boraud and David Hansel

📍 For more :

The basal ganglia (BG) are a collection of subcortical nuclei involved in motor control, sensorimotor integration, and procedural learning. They pl...

05/12/2025

New article !
📰 "Animal models of ADHD: diversity and validity"

✒️ An article by Sarah Bou Sader Nehme, Ph.D., Sandra Sánchez Sarasúa de la Bárcena, Mari-Carmen Medrano, Marc Landry and al. published in Aspet journals, Pharmacological Reviews.

📍For more :

Attention-deficit/hyperactivity disorder (ADHD) is one of the most widespread neurodevelopmental disorders globally, marked by chronic symptoms of inattention and/or hyperactivity-impulsivity. Its multifactorial origin and phenotypic heterogeneity make it a complex condition, and despite substantial...

05/12/2025

Congratulations to Eduarda Gervini Zampieri Centeno, winner of the 2025 Open Science Thesis Award 🏆

Organized for the first time in 2024, the Open Science Thesis Award aims to encourage and highlight open science practices among doctoral students.
The award recognizes theses in which open science practices have contributed to the quality of the scientific work.

📍 For more : https://imn.u-bordeaux.fr/en/2025/12/04/eduarda-centeno-winner-of-the-2025-open-science-thesis-award/

Bordeaux Neurocampus

Institut des Maladies Neurodégénératives

01/12/2025

Alexandra Dupic, interne en neurologie, a eu l'occasion d'interviewer Pierre Burbaud, neurologue et professeur des universités - praticien hospitalier à l'IMN sur l'impact qu'ont les habitudes sur le développement cérébral 🧠

📍 Interview :

Je suis neurologue, PU-PH, avec un parcours un peu atypique.

19/11/2025

New article !
📰 "Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson’s disease" 🐭

✒️ An article by Rémi Kinet, Marie-Laure Arotçarena, Evelyne Doudnikoff, Anna Lovisotto, Marie-Laure Thiolat, nathalie dutheil, Claire Mazzocco, François Georges, Erwan Bezard, Pierre-Olivier Fernagut, Benjamin Dehay and al. published in NPJ Parkinson Disease.

📍 For more :

Mutations in the ATP13A2 gene were identified as the cause of Kufor-Rakeb syndrome (KRS), a juvenile-onset form of Parkinson’s disease (PD). Developing relevant and predictive models for the rare PD forms is necessary to understand the pathological mechanisms and validate therapeutic strategies. H...