Virology and phage Research Group

22/01/2025

Welcome to Virology and Phage Research group

21/12/2024

Hello Professors and Researchers,

We have recently launched a special research topic, 'Bacteriophages and Phage-Engineered Products for Antibacterial and Anticancer Applications,' in collaboration with the Frontiers in Microbiology journal. The goal of this research topic is to provide a comprehensive understanding of the potential of bacteriophages, the challenges, and implications for revolutionizing the landscape of antibacterial and anticancer applications, with a strong emphasis on both in-vitro and in-vivo studies.

We encourage the submission of original research articles, reviews, mini-reviews, short communications, opinion articles, methods, and others that collectively cover a wide spectrum of areas, attracting a broad audience. Kindly consider submitting your research to this special issue, as it is meticulously reviewed by a dedicated editorial team in Bacteriophage research.

https://www.frontiersin.org/research-topics/61271/harnessing-bacteriophages-and-phage-engineered-products-for-antibacterial-and-anticancer-therapies-challenges-and-opportunities

26/11/2023

Bacteriophages and Phage-Engineered Products for Antibacterial and Anticancer Applications

Bacteriophages, nature's microscopic and most abundant biological entities, have been extensively studied for their potential in combating bacterial infectious diseases and also for anticancer applications.
The urgency to find alternatives to antibiotics, due to the increasing figures of antibiotic resistance, is accelerating efforts to harness and explore these bio-nanoparticles. Recent advances in phage-virus hybrids and phage protein engineering (e.g., capsid, tail, peptide, or enzyme) have broadened their applications to various industrial uses.
The goal of this research topic is to offer a comprehensive understanding of the bacteriophages’ potential, the challenges, and the implications for revolutionizing the landscape of antibacterial and anticancer applications, with a strong emphasis on both in-vitro and in-vivo studies.
Therefore, this topic aims to disseminate cutting-edge research on antibacterial and anticancer therapies, stimulate discussion, and advance our understanding of bacteriophages and phage-engineered products in clinical microbiology.
We encourage the submission of original research articles, reviews, mini-reviews, and methods that collectively cover a wide spectrum of subtopics, including, but not limited to:

1. Targeted Therapeutic Applications of Bacteriophages Against Antibiotic-Resistant Bacterial Strains
2. Engineering Bacteriophages for Enhanced Antibacterial Efficacy: A Molecular Approach
3. Exploring Bacteriophage-Derived Products for Antibacterial Coatings in Medical Devices
4. Phage-Based Approaches for Combating Biofilm-Associated Antibiotic Resistance
5. Bacteriophages as Precision Medicine: Tailoring Therapies for Antibiotic-Resistant Infections
6. PhagePhage-engineeredEngineeredclesTargeted Antibacterial Drug Delivery
7. Bacteriophages in Cancer Therapy: Selective Targeting of Tumor-Associated Bacteria
8. Phage-Induced Modulation of Tumor Microenvironment for Enhanced Anticancer Effects
9. Development of Bacteriophage-Loaded Hydrogels for Localized Antibacterial and Anticancer Treatment
10. Genetic Engineering of Bacteriophages for Synergistic Antibacterial and Anticancer Activity
11. Bacteriophage-Mediated Immunomodulation in Anticancer Therapy
12. Phage-Engineered Antibacterial and Anticancer Vaccines: A Dual-Action Strategy
13. Bacteriophage-Mimicking Nanoparticles for Antibacterial and Anticancer Applications
14. Combinatorial Approaches: Integrating Bacteriophages with Conventional Antibiotics in Anticancer Treatment
15. Bacteriophage-targeted therapy for Simultaneous Antibacterial and Anticancer Effects

Bacteriophages, nature's microscopic and most abundant biological entities, have been extensively studied for their potential in combating bacterial infectious diseases and also for anticancer applications.The urgency to find alternatives to antibiotics, due to the increasing figures of antibiotic r...

17/01/2023

A recent article "Accessing the In Vivo Efficiency of Clinically Isolated Phages against Uropathogenic and Invasive Biofilm-Forming Escherichia coli Strains for Phage Therapy" published in demonstrates the efficiency of specific and non-specific phages exhibiting depolymerase activity against biofilm-forming uropathogenic/invasive E.coli strains.

Bacteriophages as natural enzyme-bound nanoparticles!

Bacteriophage therapy getting more interesting!

https://lnkd.in/dZHEZbCG

Virology and phage Research Group George Eliava Institute of Bacteriophage, Microbiology and Virology Eliava Phage Therapy Center International Bacteriophage Research Consortium Bacteriophage Bacterion Bacteriophage.news Bacteriophage Antibacterial resistance Antibac Antimicrobials Working Group Philippine Antimicrobial Awareness Week Escudo Antibacterial InflammatoryBowelDisease.net

Escherichia coli is one of the most common members of the intestinal microbiota. Many of its strains are associated with various inflammatory infections, including urinary or gut infections, especially when displaying antibiotic resistance or in patients with suppressed immune systems. According to....

17/01/2023

The effect of RNA viruses like MS2 phages can have adverse effects in deceased conditions like Cancer! It can be a good model virus for Coronavirus research!

Our recent article published in Oncology letters predicts the possible role of viruses and how they might affect humans with prostate cancer!

https://lnkd.in/dgiHMn3e


Virology and phage Research Group Cancer Biology and Therapies WSVirology Bacteriotherapy Bacterion Eliava Phage Therapy Center Virology and Phage research The Phage Page Bacteriophage.news SEA PHAGES - FCB UANL Phage The Breast Cancer Site by GreaterGood National Cancer Institute International Bacteriophage Research Consortium Bacteriophage Bacteriophage Bacteriophage

Bacteriophages effectively counteract diverse bacterial infections, and their ability to treat most types of cancer has been explored using phage engineering or phage‑virus hybrid platforms. In the present study, it was demonstrated that the bacteriophage MS2 can affect the expression of genes ass...

24/11/2021

Please support Virology and Phage research WSVirology World Society for Virology our groups/phages by providing your review and comments.👍🤗
We also request to share valuable published information and research work with short discription of its background and important findings ...😇

03/10/2021

Our recently published communication shows Bacteriophages as an effective model nano-particle (natural) for in-vivo anticancer therapies along with its therapeutic potential ........🥳🎉😇



This Week in Virology Microbiology, immunology, virology, infectious disease department VirolVlog World Society for Virology
Virology American Cancer Society Cancer Research UK Shaukat Khanum Memorial Cancer Hospital and Research Centre

https://www.mdpi.com/2079-6382/10/10/1202/pdf

02/09/2021

Natural Bacteriophages can affect cancer cell viability and gene expression significantly!

Modified bacteriophages will be of great potential in cure for cancer in near future 🥳...

Wild-type or engineered bacteriophages have been reported as therapeutic agents in the treatment of several types of diseases, including cancer. They might be used either as naked phages or as carriers of antitumor molecules. Here, we evaluate the role of bacteriophages M13 and T4 in modulating the....

28/01/2021

Phage-encoded endolysins

Phage future and potential alternative for antibiotics against resistant bacterial pathogens!

Due to the global emergence of antibiotic resistance, there has been an increase in research surrounding endolysins as an alternative therapeutic. Endolysins are phage-encoded enzymes, utilized by mature phage virions to hydrolyze the cell wall from within. There is significant evidence that proves....