Intensive Care Medicine

Intensive Care Medicine The official page for ICM, Intensive Care Medicine.

ICM is an international peer-reviewed medical journal intended for all those who are involved in intensive care medicine. ''Intensive Care Medicine'' is the publication platform for the communication and exchange of current work and ideas in intensive care medicine. The journal publishes original research papers, reviews, as well as discussions on technology, methods, new apparatus and modificatio

ns of standard techniques and correspondence concerning matters of topical interest or relating to published material. Official journal of The European Society of Intensive Care Medicine and The European Society of Paediatric and Neonatal Intensive Care.
12 issues per year.

https://zurl.co/BWYma Severe traumatic brain injury poses major challenges where invasive ICP monitoring is unavailable....
23/05/2026

https://zurl.co/BWYma Severe traumatic brain injury poses major challenges where invasive ICP monitoring is unavailable. Bedside tools such as optic nerve sheath ultrasound, transcranial Doppler and automated pupillometry can support a multimodal strategy, with at least two methods used together. CREVICE, B-ICONIC and BOOTStraP offer stratified frameworks, while tele-neurocritical care can link frontline clinicians with specialist support.

https://zurl.co/l63pP Invasive intracranial pressure monitoring remains the gold standard for measurement and treatmen...
22/05/2026

https://zurl.co/l63pP Invasive intracranial pressure monitoring remains the gold standard for measurement and treatment. Non-invasive methods include transcranial Doppler, optic nerve sheath diameter ultrasound, automated pupillometry, skull expansion monitoring and brain imaging. These tools cannot replace invasive monitoring, but may support patient selection, risk assessment and bedside management.

https://zurl.co/MeUko Physiological data suggested a more nuanced view of respiratory mechanics in critically ill obese ...
22/05/2026

https://zurl.co/MeUko Physiological data suggested a more nuanced view of respiratory mechanics in critically ill obese patients. A Bayesian meta-analysis of four longitudinal studies including 329 patients found no robust association between BMI and chest wall elastance. Ecw values remained within similar ranges across BMI categories, while PEEP appeared to exert greater influence, although evidence remained weak because credible intervals were wide and overlapping.

https://zurl.co/NnYcx Coma of unknown origin requires early stabilization of airway, breathing and circulation, followed...
21/05/2026

https://zurl.co/NnYcx Coma of unknown origin requires early stabilization of airway, breathing and circulation, followed by focused history and neurological scoring. CT, MRI, EEG, blood tests and CSF analysis provide complementary evidence when selected according to clinical findings. The strategy prioritizes reversible causes and limits unnecessary or falsely reassuring tests. Regular reassessment is needed because coma and treatment response can change rapidly after interventions.

https://zurl.co/X1zwv -Quizz Stroke mimics can account for up to 30–50% of suspected strokes in the ED. Bilateral, sy...
21/05/2026

https://zurl.co/X1zwv -Quizz Stroke mimics can account for up to 30–50% of suspected strokes in the ED. Bilateral, symmetrical lesions with clear anatomical delineation can indicate toxic or metabolic causes. Brain MRI showed a lentiform fork sign attributed to metformin-associated lactic acidosis, with severe lactic acidosis, dehydration and acute renal failure.

-Quizz An 87-year-old man with hypertension and type 2 diabetes, treated with metformin, irbesartan, acarbose, esomep...
20/05/2026

-Quizz An 87-year-old man with hypertension and type 2 diabetes, treated with metformin, irbesartan, acarbose, esomeprazole and pravastatin, presented to the ED with rapidly worsening altered mental status, aphasia and dysarthria after a recent flu-like illness. MRI was performed after stroke code activation, before laboratory results were available. He was admitted to ICU with worsening neurological status. Which diagnosis best fits the MRI and clinical context?

https://zurl.co/7dXYD A survey of REMAP-CAP investigators found strong interest in further corticosteroid research in co...
20/05/2026

https://zurl.co/7dXYD A survey of REMAP-CAP investigators found strong interest in further corticosteroid research in community-acquired pneumonia. Priority areas included hydrocortisone in severe CAP, corticosteroids in influenza-related CAP, non-hydrocortisone glucocorticoids and fludrocortisone. Future trials using a no-corticosteroid control arm in severe CAP may be difficult because of unwillingness to randomize and contamination risk.

https://zurl.co/h6hMY Data covered 2003 adults with acute leukemia admitted to 55 ICUs in 19 countries, mostly with acut...
19/05/2026

https://zurl.co/h6hMY Data covered 2003 adults with acute leukemia admitted to 55 ICUs in 19 countries, mostly with acute myeloid leukemia and early disease-phase ICU admission. ICU mortality was 45% overall and 66% among patients requiring mechanical ventilation, while vasopressors and renal replacement therapy were frequent. Survival improved over time, especially among ventilated patients, while older age and life-sustaining therapies remained associated with ICU mortality.

https://zurl.co/ZAHDM A 55-year-old male was found comatose and presented with systemic hypothermia, hypotension, hypoxe...
19/05/2026

https://zurl.co/ZAHDM A 55-year-old male was found comatose and presented with systemic hypothermia, hypotension, hypoxemia, profuse diaphoresis and bilateral miosis. Toxicological analysis confirmed organophosphate poisoning. Brain MRI showed multifocal 2–10 mm hypointense microbleeds, mainly in the corpus callosum and juxtacortical white matter, with no significant edema or ischemic lesions. The distribution was highly specific for CI-CMBs.

https://zurl.co/tqm6v Among 251 randomized controlled trials, most evaluated AKI prevention, with outcomes mainly focu...
18/05/2026

https://zurl.co/tqm6v Among 251 randomized controlled trials, most evaluated AKI prevention, with outcomes mainly focused on renal function and renal damage. Measurements often relied on serum creatinine or AKI criteria, usually within the first week after inclusion. Therapeutic trials more often assessed renal recovery, renal replacement therapy outcomes and mortality, with timing from 7 to 90 days.

https://zurl.co/SP1hW The 2026 Surviving Sepsis Campaign guidelines used a structured process to prioritize questions by...
18/05/2026

https://zurl.co/SP1hW The 2026 Surviving Sepsis Campaign guidelines used a structured process to prioritize questions by clinical importance, sepsis specificity, practice variation and evidence likely to support graded recommendations. Vasopressor weaning evidence was described as growing but limited and focused mainly on weaning-associated hypotension. Larger trials assessing patient-important outcomes are welcomed.

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