10/10/2025
Happy World Mental Health Day!
Did you know that the use of antidepressants in the UK almost doubled between 2010 and 2021?
(https://tinyurl.com/3a32hwem)
Why do we still use antidepressants as the first or the single treatment approach for depression when we know that diet and lifestyle play a huge role in mental health? Using an approach that focuses on diet and lifestyle can be very effective in many cases. We know that antidepressants are linked to many (and some serious) side effects and patients need to be very carefully weaned off them when they want to stop using them.
We now know that inflammation, gut health and diet quality are the big drivers of symptoms in depression and other mental health conditions. When your gut is inflamed your brain can become inflamed. Reducing gut and neuroinflammation via an anti-inflammatory diet can be as effective as medication in some cases and can also increase the efficacy of medications. A 2019 systematic review also found that low-grade inflammation reduced the effectiveness of antidepressants, while an umbrella review from 2024 linked the consumption of ultra-processed foods to 32 adverse health outcomes, including common mental health disorders.
(https://doi.org/10.3389/fpsyt.2019.00458
https://doi.org/10.1136/bmj-2023-077310)
A paper from 2018 (PMID: 30254980) analysed foods for their antidepressant nutrient content (the nutrients being folate, iron, omega-3 fatty acids, magnesium, potassium, selenium, B1, vitamin A, B6, B12, C and zinc) and gave them an antidepressants food score. The top scoring foods were oysters, mussels and other seafoods, and organ meats for animal foods, and leafy greens, lettuces, peppers, and cruciferous vegetables for plant foods.
Another paper (PMID: 39756916) showed that a high dietary intake of live microbes (that you get from fermented probiotic foods) may be associated with a lower risk of depression as well as improvements in bowel habits. The study found that participants with hard and loose stools had a higher risk of depression than those with normal stools, and participants with depression had a higher risk of hard and loose stools than those without depression.
What a beautiful demonstrations of the gut-brain axis in action! ๐ฅฆ ๐ฉ ๐ง
An anti-inflammatory, gut-friendly and minimally processed diet is your insurance against many illnesses, including mental health disorders. So make sure to include some healthy fats, good quality protein, plenty of colourful foods and some fermented foods, in your home-cooked daily meals.