PluchinoLab - Regenerative Neuroimmunology

12/04/2026

Join the Cambridge Neurological Society for a fascinating talk by Professor Stefano Pluchino, Clinical Professor of Regenerative Neuroimmunology at the University of Cambridge.

Professor Pluchino is a leading figure in regenerative neuroimmunology, whose research focuses on next-generation molecular therapies for chronic neuroinflammatory conditions, including multiple sclerosis. His work has transformed our understanding of stem cell biology—shifting from simple cell replacement to recognising the critical role of intercellular signalling.

His team pioneers the use of advanced stem cell technologies, including extracellular vesicles and patient-specific 2D/3D models, to investigate disease mechanisms such as inflammation, cellular senescence, and epigenetic regulation. These innovative approaches are directly informing drug discovery and the development of targeted therapeutics.

Professor Pluchino has also led pioneering clinical trials of neural stem cells in progressive multiple sclerosis, contributing significantly to the translation of cutting-edge research into clinical applications.

This is a unique opportunity to gain insight into breakthrough advances in stem cell research and their potential to transform the treatment of neurological disease.

📆 14th April
⏰ 18:30 – 19:30

Register Here please:
https://forms.gle/Eoay2StYmjhq6Y559

30/03/2026

Inside Mexico’s stem-cell industry
Researchers in the country are calling for stronger regulation of treatments that many people make long journeys to receive.

Researchers in the country are calling for stronger regulation of treatments that many people make long journeys to receive.

27/01/2026

My interview in The National News on stem-cell treatments for MS is out — discussing promise, challenges, and the path from trials to care.

Read here ->

UAE recently used stem cell therapy for disease for first time

01/01/2026

Thanks .it for featuring our work and Leandro Perrotta for the very nice piece

Having left Sicily at 18, he found his «happy place» in Cambridge (UK), where he is a professor of Regenerative Neuroimmunology. Italy? «It trains talents but doesn't know how to make them flourish, and it doesn't attract any from abroad»

22/12/2025

Seoul trip

22/12/2025

Society for Neuroscience conference in

18/12/2025

18/12/2025

14/12/2025

✨ Had a fantastic experience speaking at the Cell Press Beijing Conference 2025 on 'Cell and Gene Therapies for Neurological Conditions'! 🌟 Engaging with cutting-edge science and inspiring discussions was a privilege

18/11/2025

Researchers identify a new cell type that may drive progressive MS

Wednesday 12 November 2025
Dr Caroline Wennington

Researchers from our Cambridge Centre of Excellence have made a discovery that could lead to new ways to treat MS progression. They’ve identified an unusual type of brain cell that seems to actively fuel the slow, ongoing inflammation and nerve damage seen with the condition.

Researchers from our Cambridge Centre of Excellence have made a discovery that could lead to new ways to treat MS progression. They’ve identified an unusual type of brain cell that seems to actively fuel the slow, ongoing inflammation and nerve damage seen with the condition.

15/10/2025

The Rogue Cell: Scientists Uncover a Key Driver of Progressive Multiple Sclerosis

Researchers at Cambridge University have identified a strange, malfunctioning brain cell that reverts to a developmental state while aging prematurely, fueling the chronic inflammation that defines this debilitating disease.

Researchers have identified a strange, malfunctioning brain cell that reverts to a developmental state while aging prematurely, fueling the chronic inflammation that defines this debilitating disease. Multiple sclerosis (MS) is a relentless condition where the body's own immune system turns against....

10/10/2025

‘Disease in a dish’ study of progressive MS finds critical role for unusual type of brain cell

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease. The discovery, reported today in Neuron, is a significant step towards understanding the compl...