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Bespoke Cbd UK Ltd, Teesside, Durham (2026)

16/01/2026

If you have cancer, build up a short intense bout of exercise into your day. Just 10 minutes of hard workout releases molecules into the bloodstream that switch on DNA repair and shut down cancer growth signals.

Researchers at Newcastle University discovered that exercise raises the levels of several small molecules in the blood that reduce inflammation, support healthy blood vessels, and improve metabolism.

When they exposed bowel cancer cells in the lab to blood containing these exercise-driven molecules, they observed widespread genetic changes. More than 1,300 genes shifted their activity, including genes involved in DNA repair, energy production, and cancer cell growth.

Although it’s great to do intense exercise every day, the researchers discovered that even one 10-minute workout started to trigger the healing process.

But it’s not just for people who have cancer. The researchers reckon that any activity—such as walking or biking or doing the gardening—reduces the risk of bowel cancer by around 20 percent. While their focus has been on bowel cancer, it’s likely that exercise will have a similar positive impact on other cancers, too

13/01/2026

The page is having some issues. I don't know what or why🫣
One says page has been suspended from being recommendations and then it clearly no violations

It's happened before and I expect it to get shut down at some point because we help people. We help people who get let down by the overstretched n h s.

12/01/2026

Few historic and fun facts on cannabinoids for research and educational purposes 😆

The World's Oldest "Vipers": Around 2,500 years ago, mourners in the Pamir Mountains of western China were already using cannabis. They burned the plants in wooden braziers during burial ceremonies, possibly to "communicate" with the deceased.

The First Medical Record: In 2737 B.C., the Chinese Emperor Shen Nung, often called the father of Chinese medicine, was the first to document the plant’s medicinal uses in his pharmacopeia.

The Scythian "Sauna": Around 450 B.C., the Greek historian Herodotus described the Scythians—nomadic warriors—throwing cannabis seeds onto red-hot stones inside felt tents to create a psychoactive steam bath that made them "shout for joy".

Surprising Historical Facts
The First Online Sale: Long before eBay or Amazon, the first-ever e-commerce transaction was a cannabis deal. In the early 1970s, students at Stanford University used ARPANET (the precursor to the internet) to arrange a purchase with students at MIT.
The Original "Canvas": The word "canvas" actually derives from the word "cannabis". For centuries, h**p was the go-to material for high-strength sails and ropes that powered the global age of exploration.
Founding Farmers: In 1619, the Virginia Assembly passed a law requiring every farmer to grow h**p. Early U.S. leaders like George Washington and Thomas Jefferson were active h**p farmers, using it for everything from fishing nets to clothing.

Cultural Oddities
Easter Island Mystery: One theory suggests the massive statues on Easter Island were "walked" into place using heavy h**p ropes and a rocking motion, rather than being rolled on logs.
The 420 Legend: The term "420" didn't start with a police code; it was a secret meeting time (4:20 p.m.) for a group of San Rafael High School students in 1971 who met by a statue of Louis Pasteur to search for a "lost" cannabis crop.
Royal Relief: Queen Victoria’s personal physician reportedly prescribed her cannabis to help alleviate menstrual cramps.

09/01/2026

A lot of people have been poorly lately , flu, colds , weak , lethargic

I too was feeling unwell, I focused on the basics that help the body recover naturally and safely. Here’s what I done:

1. Rested properly
Your body heals when you rest. I’d slowed down, slept more, and avoided pushing through fatigue, missed the gym and only walked the dog on shorter walks

2. Hydrateed well
Water with a touch of lemon, ginger and herbal teas, they help prevent dehydration and support recovery – especially if you have a fever or cold.

3. Eat simple, nourishing food
Things like:
Soup or broth
Eggs, rice, oats
Fruit (especially oranges, berries, bananas)
Veg like carrots, spinach, and potatoes
Nothing too heavy or greasy.

4. Support the immune system
I’d make sure I was getting:
Vitamin C (fruit, veg)
Vitamin D (supplement in the UK, especially in winter) I had big doses 50000iu per day
Zinc (eggs, meat, seeds)

5. Manage symptoms
Sore throat → warm drinks, honey & lemon
Congestion → steam inhalation
Aches/fever → paracetamol (if safe for you)
I used a herbal remedy 😆

6. Fresh air & gentle movement
If I felt up to it, a short walk or opening windows helps circulation and mood.

7. Listen to my body
If symptoms had worsened, lasted more than a few days, or included chest pain, high fever, or breathing problems, I’d of contacted a GP or NHS 111.

08/01/2026

For research and educational benefits only 🙏

Key Potential Benefits of RSO

Chronic Pain Relief: One of the most common uses for RSO is managing persistent, severe pain from conditions like arthritis, neuropathy, and fibromyalgia.

Cancer Symptom Support: Many patients use RSO to help with chemotherapy-related side effects, such as nausea, vomiting, and loss of appetite.

Sleep and Insomnia: Due to its high THC content and often indica-heavy profile, RSO is frequently used as a powerful sedative to help with deep, restorative sleep.

Anti-Inflammatory Properties: The full spectrum of compounds in RSO may help reduce systemic inflammation, benefiting those with conditions like multiple sclerosis (MS) or inflammatory bowel disease (IBD).

Mental Health Support: In low, controlled doses, some users find RSO effective for reducing symptoms of anxiety and depression.

Neurological Protection: Emerging research suggests RSO may assist in managing seizures and supporting overall neurological health.

Safe Usage Tips for 2026

Start Small: Because RSO is extremely potent (often 60–90% THC), the standard starting dose is a tiny drop about the size of half a grain of rice.

Method of Use: It can be taken sublingually (under the tongue), mixed into food (like peanut butter), or applied topically to the skin.

07/01/2026

CBD trial findings 😎

Key Clinical Trials and Recent Findings (2024–2026)

Harvard/McLean Hospital Study (2025): A small, open-label trial observed 12 adults with moderate-to-severe anxiety taking a full-spectrum sublingual CBD product (30 mg/day). Participants reported significant reductions in anxiety within the first week, alongside improvements in mood and sleep.

CBD for Stress (SCANS Trial, 2025–2026): This Phase 2 trial investigated how oral CBD affects the body's stress response, brain function, and hormones in individuals with high stress or past trauma.

Meta-Analysis of Randomized Controlled Trials (2025): A comprehensive review of 12 trials concluded that daily doses of 30 mg or less provided the most consistent benefits for anxiety and sleep without significant adverse events.

Hemp-Derived CBD for Anxiety (NCT06672666, 2026): An ongoing 4-week, double-blind, placebo-controlled trial is testing doses ranging from 50 mg to 150 mg per day to assess efficacy in improving anxiety symptoms and sleep disturbances.

Broad-Spectrum vs. Isolate Study (2024): A quasi-experimental study of nearly 400 volunteers found that both CBD isolate and broad-spectrum products were effective for stress management, though participants rated the broad-spectrum product as significantly more effective for stress reduction.

Ongoing Research Areas

Social Anxiety Disorder (SAD): Recent trials have utilized doses of 300–800 mg/day for adolescents and young adults with treatment-resistant anxiety, showing significant symptom reduction.

Stress Task Responses: Ongoing trials use standardized stress tasks and functional MRI (fMRI) to observe how CBD modulates brain activation during fear learning and extinction.

Bioavailability and Titration: Current research like NCT03549819 is focusing on flexible dosing and biological markers (like inflammation) to better understand the relationship between CBD and anxiety.

06/01/2026

It's always a pleasure receiving feedback 🙏

How CBD Helps Anxiety

CBD works through several biological mechanisms in the central nervous system:

Serotonin Regulation: CBD interacts with 5-HT1A receptors, which are key targets for traditional anti-anxiety medications. It may help the brain use available serotonin more effectively to stabilize mood.

Endocannabinoid System (ECS) Support: It inhibits the enzyme (FAAH) that breaks down anandamide, a naturally occurring "bliss" molecule in the body, thereby increasing its calming effects.

GABA Boosting: Some research suggests CBD indirectly prevents a decrease in GABA, a neurotransmitter that slows down brain activity to induce relaxation.

Amygdala Activity: Neuroimaging studies show that CBD can reduce blood flow to and activity in the amygdala, the brain's "fear center," helping to dampen the physiological response to stress.

Determining the appropriate CBD dosage for anxiety is not a one-size-fits-all approach, as it can depend on individual factors such as body weight, metabolism, and the severity of anxiety symptoms.

It is generally recommended to begin with a low dose and gradually increase it over time while observing the effects. This method allows individuals to assess their tolerance and identify the minimal effective dose.

Important Considerations:

Titration: Adjusting the dosage slowly over time helps in finding the optimal amount.

Product Type: The type of CBD product used, such as full-spectrum, broad-spectrum, or isolate, may influence the effects. Full-spectrum products contain a range of cannabinoids and other h**p compounds, which some believe can enhance effectiveness due to the "entourage effect".

05/01/2026

The Benefits of CBD (Cannabidiol)

CBD is a non-psychoactive compound primarily used for everyday wellness.

Pain & Inflammation: Studies suggest CBD interacts with receptors like TRPV-1 to reduce pain signals, particularly for conditions like osteoarthritis and fibromyalgia.

Mental Health: Research indicates CBD may reduce subjective symptoms of anxiety and depression by binding to serotonin receptors.

Sleep Support: Low doses (e.g., 15mg) have been found to be as effective as melatonin for improving sleep quality in some users by reducing racing thoughts and discomfort.

Neuroprotection: Beyond FDA-approved uses for severe epilepsy, preliminary evidence suggests potential benefits for neurodegenerative diseases like Parkinson’s and MS.

The Benefits of FECO (Full Extract Cannabis Oil)

FECO is a highly concentrated, thick, "whole-plant" extract. It is often distinguished from standard CBD oil by its broader molecular profile and higher potency.

The Entourage Effect: FECO captures the full spectrum of cannabinoids (THC, CBD, CBG, etc.) and terpenes, which work synergistically to enhance therapeutic outcomes.

Targeted Chronic Relief: Because of its potency, FECO is frequently preferred for complex or chronic conditions, including severe chronic pain and cancer-related symptoms like nausea and appetite loss.

Slow-Release Efficacy: FECO’s high concentration typically provides longer-lasting effects than isolated oils, making it a choice for sustained relief through the night or a full day.

Which to Choose?

CBD Oil is generally best for mild to moderate wellness needs, such as occasional stress or localized muscle soreness.

FECO is ideal for those requiring deeper, systemic support for persistent or multifaceted symptoms.

02/01/2026

We’ve all heard the old saying, "Prevention is better than cure." But in 2026, this isn't just a proverb—it’s a necessity for a high-quality life.

Think of your health like a high-performance car. You wouldn’t wait for the engine to seize before checking the oil, right? Your body deserves the same proactive care.

Why Prevention Wins Every Time:

💰 It Saves Your Wallet: Treating advanced diseases like diabetes or heart conditions is exponentially more expensive than regular screenings and healthy habits.

🛡️ It Saves Your Future: Many serious conditions, including nearly 40% of cancers and 80-90% of throat cancers, are preventable through lifestyle choices.

⚡ It Boosts Your Energy: When you prioritize sleep, hydration, and movement today, you aren't just "not sick"—you’re thriving with better focus and mood.

🕒 It Saves Your Time: A 15-minute check-up today can save you from weeks or months in a hospital bed tomorrow.

3 Simple "Prevention First" Steps for 2026:

Know Your Numbers: Don't guess. Schedule your routine blood pressure, cholesterol, and glucose checks.

Move Daily: Even a 10-minute walk after meals makes a massive difference for your metabolic health.

Listen to the Whispers: Don't ignore small signs like fatigue or persistent stress. Your body is talking to you!

Let’s stop being reactive and start being proactive. Your future self will thank you. ❤️

If your starting to struggle or have an illness and would like some ideas on how to help yourself.
Drop us a message and we will help you start researching some natural methods, excersise routines , diet plans to kick start your healing journey 🙏

What’s ONE small preventive habit you’re starting this week? Let us know in the comments! 👇

25/12/2025

Good morning you beautiful people

We wish each and everyone of you a very special Christmas.
You are loved , you are amazing and people need to see your beautiful face and that radiant Smile 😁

Id also like to take this opportunity to thank you all for your continued support in allowing us to be apart of your healing journey

Merry Christmas 🎄🎁🙏

Bespoke Cbd UK Ltd

16/01/2026

13/01/2026

12/01/2026

09/01/2026

08/01/2026

07/01/2026

06/01/2026

05/01/2026

02/01/2026

25/12/2025

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Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm
Friday	9am - 5pm
Saturday	9am - 12pm