Scottish Intercollegiate Guidelines Network (SIGN)

17/02/2026

Share your views on our guideline on the management of chronic pain.

Part 1 of the SIGN guideline on Management of chronic pain was published in December 2025. Part 2 of the SIGN guideline on Management of chronic pain is now open for consultation. This part includes recommendations and guideline content on:
• simple analgesics
• antiepileptics
• muscle relaxants
• topical analgesia
• combination pharmacological therapies
• physical therapies (hands-off)
• physical therapies (hands-on)
• electrotherapy
• dietary interventions, and
• alternative therapies
in people with chronic pain.

We are primarily interested in your view on the comprehensiveness and accuracy of the interpretation of the evidence base supporting the guideline recommendations, and any comments on the style or presentation would also be welcome.
Please access part 2 of the draft SIGN guideline on Management of chronic pain at https://www.sign.ac.uk/get-involved/comment-on-a-draft-guideline/, where you will also find an online survey to submit your comments. Feedback can be submitted until 12pm on Wednesday, 11 March 2026.

25/09/2025

The Medicines and Healthcare products Regulatory Agency (MHRA) has published a reminder that taking paracetamol during pregnancy remains safe. Read our Trusted Advice on paracetamol in pregnancy https://www.sign.ac.uk/

03/02/2022

As we publish our guideline on eating disorders, Ellen Maloney, a patient representative on the guideline group, shares her experience of living with anorexia nervosa and outlines the changes she hopes the guideline will bring.

Read Ellen’s blog: bit.ly/3u4BJ1B

03/02/2022

The Mental Welfare Commission says our new guideline on eating disorders gives key recommendations which will improve the care and treatment of people living with eating disorders in Scotland.

Read more: https://www.sign.ac.uk/our-guidelines/eating-disorders/

03/02/2022

Our guideline on eating disorders had published. Read about the recommendations here:
https://www.sign.ac.uk/our-guidelines/eating-disorders/

22/11/2021

The patient version of the SIGN guideline on eating disorders is available for consultation until 16 December. The consultation can be found here https://www.sign.ac.uk/patient-and-public-involvement/consultations/

03/03/2021

We’re working with and to develop a guideline for the diagnosis, monitoring and management of chronic asthma. We are looking for co-chairs and topic advisors to join us in developing this important work.
www.nice.org.uk/get-involved/our-committees/join-a-committee/chair--diagnosis-and-management-of-chronic-asthma
www.nice.org.uk/get-involved/our-committees/join-a-committee/topic-expert--diagnosis-and-management-of-chronic-asthma

30/09/2020

Now available on our website sign.ac.uk. If you'd like to order the quick reference guide, please email sign@sign.ac.uk with the quantity you would like and your delivery address.

25/06/2020

This great blog from our Chair shows how SIGN has adapted to provide guidance during the COVID-19 pandemic.
https://blog.healthcareimprovementscotland.org/2020/06/24/how-the-covid-19-infodemic-is-changing-the-way-we-look-at-evidence/

28/05/2020

Does the Evidence Support the Hype? COVID-19 and Antiviral Treatments 05/29/2020 12:00 p.m. to 12:45 p.m. EDT (Webinar) The magnitude of the COVID-19 pandemic globally is generating considerable interest in options to prevent infection and minimize the impact if infection occurs. Pre-exposure prophy...

17/04/2020

Interesting project to help make sense of the ever-increasing evidence on COVID-19.

A growing number of studies and reports are being published on COVID-19 and the pandemic. This project will help decision makers and researchers navigate the research.