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SynMed

SynMed (previously trading as Synectics Medical) is one of the UK’s leading suppliers of diagnostic and therapeutic equipment in gastroenterology

SynMed
SynMed House
Unit 7, The Pavillions
6 Kinetic Crescent
Innova Park
ENFIELD
EN3 7FJ

13/01/2026

First U.S. experience with BARS® for anastomotic revision after RYGB

This case series demonstrates that BARS enables successful endoscopic gastrojejunal anastomosis (GJA) revision with clinically meaningful early weight loss and rapid procedure times
Key findings
• 100% technical success rate with ≥70% anastomotic reduction
• Mean total body weight loss of 10.5% at 1 month (range: 6.0-13.5%)
• Mean BMI reduction of 3.5 kg/m² at 1 month (range: 2.0-4.5 kg/m²)
• Significant reduction in procedure time with experience: from 48 minutes (first case) to 19 minutes (third case)
• No major complications; all patients discharged within 1-2 days
Study details
• Retrospective case series (n=3) at Cleveland Clinic Foundation, Cleveland, Ohio
• Patients with weight regain after Roux-en-Y gastric bypass and dilated GJA (>15 mm; range: 20-60 mm)
• Aim: Evaluation of safety, efficacy, and technical feasibility of BARS® for endoscopic GJA revision

Firkins SA, Sierra L, Khurana A, Chatterjee A, Patel R, Flora B, Staneff E, Simons-Linares R. Raising the BARS: First U.S. Experience of a Novel System for Endoscopic Gastrojejunal Anastomosis Revision. Techniques and Innovations in Gastrointestinal Endoscopy. 2025;250944. doi: 10.1016/j.tige.2025.250944 .

Email sales@synmed.co.uk for more information

05/01/2026

The power of OTSC®neo with the OTSC® Twin Grasper® in acute GI perforations. 📊

Acute gastrointestinal perforations were traditionally an absolute indication for surgery. A landmark prospective multicenter study challenged this paradigm - and demonstrated the critical role of proper tissue approximation.

Voermans et al. (2012) evaluated OTSC® closure in 36 consecutive patients with acute iatrogenic perforations across 11 European tertiary centers. All cases were treated using the OTSC® TwinGrasper® for optimal tissue approximation before clip deployment.

Why the OTSC® TwinGrasper® matters: It reduces the risk of grasping adjacent organs and enables precise grasping and approximation of both perforation edges simultaneously - ensuring full-thickness, serosa-to-serosa closure.

The results:
✅ 89% overall clinical success (32/36 patients)
✅ 92% immediate endoscopic closure (33/36 patients)
✅ 0% contrast leakage on post-procedural x-ray imaging
✅ Mean closure time: only 5 minutes 44 seconds

The clinical impact: This prospective trial demonstrated that endoscopic OTSC® closure with the OTSC® TwinGrasper® can successfully manage acute perforations across the entire GI tract.

👉 Email Sales@Synmed.co.uk to book an onsite training session or for more information on OTSC®neo - the best-studied closure device.

Key Reference: Voermans RP, et al. Clin Gastroenterol Hepatol 2012; 10(6): 603-608. DOI: 10.1016/j.cgh.2012.02.005

12/11/2025

Registration is now open for the Spring 2026 date for the Synmed Capsule Endoscopy Study Day at The Clermont, Charing Cross, London, confirmed for February 13th. If you or any of your colleagues would like to attend, register via the Synmed website; https://synecticsmedical.co.uk/capsule-endoscopy-study-day/

Aimed at all levels of experience, the key objective is to introduce you to or build on your existing practice using Capsule Endoscopy and to have "Hands-on experience" in pathology recognition and reporting, including the new ‘AI Play’ function, to ensure you get the most out of your software. There will also be opportunity for discussion and to share experiences with other centres with regards to both patient preparation and post procedure care. Finally, a chance to see the latest developments in Capsule Endoscopy and related technology from Intromedic.

Contact sales@synmed.co.uk for more information.

16/10/2025

Discover the FTRD® prOVE Cap: an essential tool for pre-procedure testing

Available in both colonic and gastroduodenal versions, these caps match the dimensions of their respective FTRD® caps, allowing you to test the viability of the FTRD® Set in advance. Whether you're preparing for a colonic or gastroduodenal procedure, the prOVE Cap provides a reliable way to simulate and assess the potential application, enhancing procedural success and in cases where the FTRD® System is not suitable for the intervention, it is saving valuable resources.

25/06/2025

Day 3 of BSG Live’25 at SEC Glasgow, visit us on the SYNMED stand to see latest developments in Motility and pH monitoring options, including;

• alpHaONE System wireless pH monitoring.
• alpHaFLEX catheter based pH/Impedance Monitoring System.
• MANOalpHa High Resolution Manometry System.
• Details on upcoming Impedance/pH Reflux Testing & HRM Clinical Training Seminar, September 3rd 2025

If you can’t make it to the SYNMED stand but would like to hear more, simply contact sales@synmed.co.uk

24/06/2025

We are at BSG Live’25, SEC Glasgow! visit us on stand C4 for ‘hands on’ training opportunities with the improved Ovesco OTSC® system- OTSC®neo, no need to pre book, just find our Ovesco booth and one of the team will welcome you.
Learn more about;
ArgoCap for the precise ablation of superficial lesions during APC treatment in the GI tract
BougieCap for the dilation of stenosis and strictures in the upper gastrointestinal tract
Hemopill a non-imaging, swallowable sensor capsule for the real-time detection of acute bleeding in the oesophagus, stomach, and small intestine.
Latest UK training options for the Ovesco Full Thickness Resection Device (FTRD).

If you're not attending BSG, remember we can always offer ‘hands on’ OTSC®neo training sessions onsite at your hospital, contact Sales@Synmed.co.uk

29/05/2025

FTRD® shows low recurrence rates and high success in treating difficult colorectal lesions

Key findings
• Colorectal FTRD® demonstrates a low overall recurrence rate of 9.9% (n=9/91)
• Majority (66.6%) of recurrent or residual lesions (RRLs) were successfully treated endoscopically. All of them occurred in non-lifting adenoma.
• No late adverse events reported
• Close follow-up is crucial for optimal outcomes, especially in non-lifting adenomas and early carcinomas

Study details
• Retrospective analysis conducted at University Medical Center Freiburg from 2014 to 2021
• Included 91 patients with at least one endoscopic follow-up examination
• Indications for FTRD®: Non-lifting adenoma (n=65), subepithelial tumors (n=18), early carcinoma (n=8)
• Median follow-up period was 17 months (range 2-86)

Mueller J, Miedtke V, Kuellmer A, Schiemer M, Bettinger D, Thimme R, Schmidt A. Outcome after colorectal full-thickness resection and management of recurrence. Endosc Int Open. 2024;12(8):E989-E995. DOI: 10.1055/a-2375-7568.

Email Sales@Synmed.co.uk for more information on training opportunities for FTRD

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21/05/2025

New case study on the OTSG Xcavator® by Karna et al. demonstrates OTSG Xcavator® effective for removal of large necrotic debris in direct endoscopic necrosectomy (DEN)*

Key findings

OTSG® Xcavator could remove large pieces of necrosum of between 10-15cm in length
Complete resolution of necrosis was achieved in two sessions
No adverse events occurred

Case details

63-year-old man with history of semaglutide-induced necrotizing pancreatitis leading to an infected walled-off necrotic collection
DEN with traditional tools such as forceps, snares and suction were challenging due to the nature of the large, thick and pasty necrotic tissue adherent to the cyst wall
After the procedure, LAMS were removed and replaced with plastic double-pigtail stents across the cystogastrostomy

Karna R, Arayakarnkul S, Wilson N, Bilal M. Successful necrosectomy using the over-the-scope grasping device: a tool for solid necrotic debris. Endoscopy. 2024;56(3):E957-E958. Doi: 10.1055/a-2443-4173

Email Sales@Synmed.co.uk for more details or to arrange a demonstration.

29/04/2025

Discover the potential of the HemoPill® acute as a triage tool!

A UK study by D'Cunha Kamath et al. explores how the HemoPill® acute was used to reduce inpatient gastroscopies.

UK study on the HemoPill® acute shows that the bleeding-detection capsule could reduce the need for inpatient gastroscopies in patients with suspected non-variceal acute upper gastrointestinal bleeding (AUGIB)

Key findings
• 10 patients were given the HemoPill® acute. The HemoPill® acute showed a negative result in 6 and a positive result in 4 patients
• Adverse events occcurred in 0 cases and 90-day mortality was 0%
• HemoPill® as a triage tool led to a reduction of inpatient gastroscopies
• Patient with suspected non-variceal AUGIB and negative HemoPill® results could be safely managed as outpatients

Study details
• All patients included had been admitted to hospital with a suspected UGI bleed. The median Glasgow Blatchford Score was 9 and the median Rockall Score 4
• No pre-procedure fasting was required
• All patients with negative capsule results were managed as outpatients and underwent urgent outpatient gastroscopy
• All patients with positive capsule results were managed as inpatients and underwent inpatient gastroscopy

D'Cunha Kamath A, Friel JH, Braddy-Green C. Novel method for risk stratifying suspected acute non-variceal upper GI bleeds using a blood-detection capsule: first UK hospital experience. Frontline Gastroenterol. 2025; flgastro-2024-102883. Doi: 10.1136/flgastro-2024-102883.
Read more; https://fg.bmj.com/content/early/2025/02/08/flgastro-2024-102883

Email Sales@Synmed.co.uk for more information

18/02/2025

FTRD® enabled R0 resection without complications of an isolated follicular lymphoma in the cecum

Key findings
• Isolated GI follicular lymphoma (GI-FL) in the cecum was referred for endoscopic treatment
• With FTRD®, R0 resection without complications was achieved. Final pathology revealed a 23x21x8mm grade 1-2 follicular lymphoma with negative margins
• Patient is clinically well in the six-month follow-up
• Authors conclude that FTRD® appears effective for small isolated colonic GI-FL

Case details
• 62-year-old woman with a sessile polyp (12mm submucosal lesion) in the cecum
• PET-CT without evidence of malignancy, bone marrow biopsy was normal without evidence of lymphoma, suggesting an isolated GI-FL
• 1-year follow-up is pending

Mauro AJ, Bell PD, McGrath K. Gastrointestinal Follicular Lymphoma of the Cecum Treated via Endoscopic Full-Thickness Resection. ACG Case Rep J. 2024;11(8):e01466. DOI: 10.14309/crj.0000000000001466 For further clinical and product information, please follow our website links on the FTRD® System.

👉 Learn more about FTRD® and its benefits: https://lnkd.in/dnBWDUM
👉 Email Sales@Synmed.co.uk for details of UK training opportunities

13/02/2025

FTRD® - a diagnostic and therapeutic option for T1 carcinoma

FTRD® is a minimally invasive alternative to surgical resection for T1 carcinomas. Through its high R0 resection rate, it offers high-quality pathological specimens for exact histologic risk stratification and can serve as a potentially curative treatment.

👉 Learn more about FTRD® and its benefits: https://synecticsmedical.co.uk/product-category/endoscopic-full-thickness-resection/
👉 Email Sales@Synmed.co.uk for details of UK training opportunities

05/02/2025

Find out more about the HemoPill® acute! 💊

Developed to help exclude or confirm bleeding in the oesophagus, stomach and small intestine, this telemetric capsule is easy to use for both patients and physician. It requires no preparation of the patient, is smaller than regular video capsules and the data is immediately available without the need for time-consuming evaluation. That way, physicians can quickly determine whether a patient has an acute GI bleeding and needs an urgent endoscopy – or whether there is no acute bleeding present and an endoscopy can instead be scheduled during regular working hours.

👉 Contact Sales@Synmed.co.uk for more information or to arrange a period of evaluation

Address

Enfield
EN37FJ

Opening Hours

Monday	9am - 5:30pm
Tuesday	9am - 5:30pm
Wednesday	9am - 5:30pm
Thursday	9am - 5:30pm
Friday	9am - 5:30pm

Telephone

+441992780570

Website

http://www.synecticsmedical.co.uk/

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