20/09/2025
Is there a "best" way to take your progesterone during IVF? 🤔 A groundbreaking new study says there might be! For anyone who's been through the emotional and physical rollercoaster of IVF, you know that every little detail matters. One of the most critical parts of the process is the "luteal phase support" – the hormones you take to help the embryo implant and grow. For years, there's been a debate about the best way to get this support.
What has been your experience with progesterone during IVF? Let's discuss! 💬✨
Tehraninejad, E.S., Alizadeh, S., Nekoo, E.A. et al. Comparing the outcomes of in-vitro fertilization in patients receiving vaginal, subcutaneous, and intramuscular progesterone for luteal phase support: a three-armed randomized controlled trial. BMC Women's Health 24, 481 (2024).
Griesinger, G., Blockeel, C., Tournaye, H. et al. Oral dydrogesterone for luteal phase support in fresh embryo transfer cycles: an individual participant data meta-analysis. Hum Reprod Open 2020, hoaa032 (2020).
Drakopoulos, P., Papatheodorou, A., Pluchino, N. et al. Comparison of luteal support protocols in fresh IVF/ICSI cycles: a network meta-analysis of randomized controlled trials. Sci Rep 14, 13735 (2024).