08/01/2026
🩺 Exciting new research reveals the causal relationship between premature ovarian insufficiency (POI) and cardiovascular diseases (CVD)! Using Mendelian Randomization, this study found that POI is linked to an increased risk of coronary heart disease (Odds Ratio 1.048) and ischemic stroke (Odds Ratio 1.010). However, no significant links were found with hypertension, heart failure, atrial fibrillation, or myocardial infarction.
These findings highlight the importance of monitoring cardiovascular health in women with POI due to the protective role of estrogen. Let's raise awareness about proactive cardiovascular management for those affected! 💖
Yang, X., Lin, T., Luo, L., Chen, H., Dai, Y., Li, D., & Zhu, L. (2025). Causal associations between premature ovarian insufficiency and cardiovascular diseases: a Mendelian randomization study. Gynecological Endocrinology, 41(1), 2487498.