Eggfreezing

Eggfreezing Egg freezing is a private service which helps women to be investigated for ageing and offers egg count tests : it is a service for preserving fertility

Fertility Plus is a unique, modern and bespoke private fertility service of the highest quality, provided in heart of London offering a very personalised and holistic approach to treatment. The ethos of Fertility Plus care is to provide a personalised and individual approach to each patient in the most flexible way. We offer appropriate advice, investigations, treatments and support, in a non-judgemental fashion, both to couples and single women. Moreover, we have adopted clear price packages which are transparent, fair and defy the open-wallet policies which many other service providers in London offer. Taking the option of having a baby in the future is an emotional and a significant choice. We aim to help women to plan their future fertility through the process of egg freezing.

🌟 Vitamin D Isn't Ruining Your IVF Chances – Here's What Really Happens (And Why You Shouldn't Panic!) 🌟Many believe vit...
08/04/2026

🌟 Vitamin D Isn't Ruining Your IVF Chances – Here's What Really Happens (And Why You Shouldn't Panic!) 🌟

Many believe vitamin D is crucial for fertility, and while it can support overall health, something interesting occurs during IVF. 🤔

In a study of over 2,500 women undergoing IVF, researchers found that high estrogen levels from fertility drugs increase levels of vitamin D binding protein (DBP). Think of DBP as a delivery truck for vitamin D! 🚚

This means total vitamin D in the blood may go up, but the free, usable form can dip temporarily. The good news? These short-term changes do NOT harm egg quality, embryo development, or your chances of getting pregnant. IVF success rates remain the same! 🌈

For most women, these fluctuations are normal and nothing to stress about. However, women with PCOS or from South Asian backgrounds might start with lower vitamin D levels. So checking and fixing low levels early can still be beneficial!

The key takeaway? Keep your vitamin D levels healthy before and during treatment – it’s one of the simplest ways to support your body. 💪✨
Chen H, Yao J, Hu L, et al. Vitamin D binding protein correlate with estrogen increase after administration of human chorionic gonadotropin but do not affect ovulation, embryo, or pregnancy outcomes. Frontiers in Endocrinology. 2024;15:1401975. doi:10.3389/fendo.2024.1401975Stop worrying about short-term vitamin D fluctuations during IVF and keep it simple!



For any inquiries or questions, email clinic@fertilityplus.org.uk

👉 Want more straightforward fertility insights like this? Follow us and subscribe for updates to stay empowered on your journey!

08/04/2026

How risky is a D&C for future fertility? 🤔

A new study tracked 58,607 women who underwent dilation and curettage (D&C) and found that only 0.8% developed scar tissue inside the womb (intrauterine adhesions). That's much lower than previous estimates!

However, if you've had multiple D&Cs, the risk increases:
• 2 D&Cs → ~4× higher risk
• 3 or more D&Cs → ~12× higher risk

Factors like obstetric reasons for the D&C or a history of pelvic inflammatory disease can also increase the likelihood of adhesions.

So, if you're facing a D&C, remember:
- For most women, one well-performed D&C has low risk.
- If you've had several D&Cs or risk factors, consider discussing alternatives and follow-up checks.

You deserve clear information to make informed decisions about your fertility journey! Would these numbers change how you view a D&C? 💭



Chen S, Samiezade-Yazd Z, Triplett C, Joshi N. Incidence and Risk Factors for Intrauterine Synechiae in Women With Previous Dilation and Curettage. Obstet Gynecol. 2026

08/04/2026

Endometrial scratch doesn’t help everyone—but may still help the right RIF patients

A comprehensive systematic review has evaluated over two decades of data concerning endometrial injury, commonly referred to as 'endometrial scratch,' and its effects on live birth rates. Initial studies indicated significant improvements; however, subsequent larger trials revealed limited benefits.

The latest review, which includes data from more than 4,100 women, indicates that while the increase in success rates is modest (with an odds ratio of 1.29), it may still be relevant for select individuals experiencing recurrent implantation failure, particularly when multiple biopsies are performed prior to embryo transfer.

It is crucial to understand that this technique may not be warranted for all IVF patients. However, it has the potential to enhance success rates for certain candidates.

We encourage you to consult with your healthcare provider to determine if this option is suitable for you.
Shoham Z, Broekmans FJM, et al. Reevaluating endometrial injury for in vitro fertilization: evidence suggests a promising approach may have been abandoned prematurely: a systematic review. Reproductive BioMedicine Online. 2025;105371. doi:10.1016/j.rbmo.2025.105371

08/04/2026

🚨 POI Pregnancies: 3,640 Studies Searched, 0 Clear Answers”🚨

A recent systematic review on idiopathic premature ovarian insufficiency (POI) reveals alarming findings: after searching 3,640 studies, researchers found no clear answers regarding pregnancy outcomes for women with POI. While there are suggestions that the risk of early miscarriage may be higher, the data remains poorly quantified. This highlights an urgent need for well-designed research to better understand these risks.

For those affected by POI, the journey to motherhood can be challenging, and this study underscores the importance of further investigation into pregnancy outcomes.

Let's advocate for more research and support for women navigating this condition!

ref: Reproductive BioMedicine Online. 2025;51(5):105426.
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Your Ovaries Are Never StillMost women come to us with a number in hand — a follicle count or an AMH result — and it oft...
08/04/2026

Your Ovaries Are Never Still

Most women come to us with a number in hand — a follicle count or an AMH result — and it often feels like a verdict. But science tells us a different story! 🌊

Follicles don’t just develop in one single wave each month; they grow in two or three synchronized pulses. Each pulse is triggered by hormonal signals, meaning your scan results can vary significantly depending on the day it’s taken. 📅

As we age, the overall pool of follicles does decline, especially after 37, but the wave pattern continues! What changes is what these waves produce. While older ovaries produce fewer small recruitable follicles, they may generate more single dominant ones.

Let’s talk about AMH — the blood test that assesses ovarian reserve. It can drop to low levels years before menopause and remain there for a while. A 35-year-old and a 47-year-old can have similar AMH results but completely different timelines ahead of them.

Remember: A single number is just a starting point, not a conclusion. Understanding the biology behind it opens up the real conversation! 💬

🌟 The 1% Factor: Why HCG Triggers Sometimes Fail 🌟Did you know that while modern fertility triggers are over 95% to 99%...
07/04/2026

🌟 The 1% Factor: Why HCG Triggers Sometimes Fail 🌟

Did you know that while modern fertility triggers are over 95% to 99% effective, there's still a small chance of failure? In about 0.5–1% of cases, hCG triggers may not work due to factors like high BMI or receptor sensitivity. GnRH analogue triggers have a slightly higher failure rate of 2–5%, often linked to deep pituitary suppression or low baseline LH.

But there's good news! The "Dual Trigger" approach—combining both hCG and GnRH—can reduce the risk of failing to retrieve any eggs to under 1%. This method provides a robust safety net for successful retrieval. 🥚✨

Stay informed and empowered on your fertility journey!
hanem, N., et al. (2023). "Luteinized Unruptured Follicle (LUF) Syndrome: Pathophysiology and Clinical Management." Journal of Assisted Reproduction and Genetics. (Discusses the role of COX-2 inhibition and high LH in PCOS patients leading to rupture failure).

Hertility Health (2024). "Luteinising Hormone: What do Your LH Levels Mean?" Clinical Review. (Explains the impact of high LH in PCOS on follicular arrested development).

BioScientifica: Reproduction (2023/2024 update). "The mare as a model for luteinized unruptured follicle syndrome." (Provides evidence for age-dependency and recurrence of unruptured follicles).

One Simple S***m Number Could Boost Your IVF/ICSI Success by 20% – Here’s What It Is! When couples face fertility challe...
07/04/2026

One Simple S***m Number Could Boost Your IVF/ICSI Success by 20% – Here’s What It Is!

When couples face fertility challenges and turn to ICSI (a type of IVF where s***m is injected directly into the egg), success isn't just about the woman's age or egg quality. A major new study shows that the man's total motile s***m count (TMSC) plays a big role too.

Researchers looked at over a thousand couples across multiple centers. When TMSC was above 15 million, fertilization rates jumped from around 45% to 65% – that's a 20% improvement! Even better, the chances of having a live birth went up by about 10% compared to lower counts.

For every extra 5 million in TMSC, fertilization improved by roughly 7%. This link held strong even after adjusting for the woman's age and other factors, making TMSC one of the strongest male-side predictors of success.

Knowing your TMSC can guide doctors to the best treatment plan, potentially raising chances while reducing time, costs, and stress. If you're exploring fertility options, asking about TMSC is a smart, simple step that could make a real difference.

For inquiries or questions, email clinic@fertilityplus.org.uk
Crafa A et al. Does total motile s***m count predict embryo quality and ICSI success in young normal-weight women? A retrospective multicentre study. Reproductive BioMedicine Online, 2026Want more tips and updates on fertility breakthroughs? Subscribe or follow now so you never miss the latest ways to improve your chances!

***mCount

07/04/2026

Shared Motherhood Without Compromise: Reciprocal IVF Matches Standard IVF Success for Same-Sex Female Couples! 🌈👩‍❤️‍👩

Imagine two women in love, both wanting to play a real biological role in building their family — one providing the eggs, the other carrying the baby. This is called reciprocal IVF (sometimes known as co-IVF or shared motherhood).

A large new US study looked at over 3,700 embryo transfers from same-sex female couples. In reciprocal IVF, one partner donates the eggs while the other carries the pregnancy. In standard (autologous) IVF, one woman does both.

The results are reassuring and hopeful: pregnancy rates were about 64% with reciprocal IVF compared to 57% with standard IVF. Live birth rates were very similar — around 52% versus 48%. That means sharing the biological journey did not reduce the chances of having a baby.

There was a small increase in preterm birth for single babies (about 14.5% vs 11.3%), but doctors already watch IVF pregnancies closely for this, and the overall difference was modest.

This large national study gives clear evidence that reciprocal IVF is a safe, effective option. Couples no longer have to wonder if wanting both partners involved means lower success — the numbers say it works beautifully. It turns an emotional wish into a medically supported reality. Perfect for couples dreaming of true shared motherhood.

For any inquiries or questions, please email: clinic@fertilityplus.org.uk
JAMA. 2026;335(10):90
If this resonates with your journey, hit follow, subscribe, and share with anyone building their family through love. Stay tuned for more inclusive fertility updates!

Miscarriage Matters: The True Scale of Early Pregnancy LossDid you know that miscarriage affects 1 in 6 pregnancies, lea...
07/04/2026

Miscarriage Matters: The True Scale of Early Pregnancy Loss

Did you know that miscarriage affects 1 in 6 pregnancies, leading to a staggering 23 million losses every year? 😢 A landmark study by Quenby et al. reveals the profound psychological, obstetric, and long-term health consequences that have often been underestimated.

It's time to address the risk factors, economic costs, and clinical implications of pregnancy loss. We must advocate for better data, specialist care, and compassionate support for women and families impacted by this heart-wrenching experience.

Join us in raising awareness and fostering understanding around this critical issue. Together, we can make a difference! 💔🤝
Miscarriage Matters" by Quenby et al., The Lancet 2021.

Ever wondered what embryologists look for after fertilising an egg? Let's talk about PN (pronuclei) – not PM! 😉👇🔍 **2PN ...
06/04/2026

Ever wondered what embryologists look for after fertilising an egg? Let's talk about PN (pronuclei) – not PM! 😉👇

🔍 **2PN (Two Pronuclei)**: This is the gold standard! The appearance of two distinct structures means the egg and s***m have joined correctly, which signifies a normally fertilised egg.

🔬 **1PN (One Pronucleus)**: This is an atypically fertilised egg showing only a single pronucleus. They occur in about 4% to 8% of IVF cycles and 2% to 5% of ICSI cycles. Because they show only one pronucleus, clinics often assume they are missing genetic material and routinely discard them. However, research shows that 1PN embryos can actually be viable, have normal genetic material, and result in healthy live births! In fact, one study found that 45.7% of 1PN-derived blastocysts were diploid (having a normal set of chromosomes). Another study confirmed that when 1PN embryos were created via traditional IVF, a whopping 75% were normal!

⚠️ **3PN (Three Pronuclei)**: These zygotes can experience developmental errors, as they usually result from one egg being fertilised by two s***m, giving an extra set of chromosomes.

Understanding these details can make a world of difference in reproductive science! 🧬💖

06/04/2026

Many women with PCOS are told their hormones are the problem. But research reveals a deeper story. A large study found that women with PCOS are 40-50% more likely to develop type 2 diabetes, even at similar weights. However, the average woman with PCOS weighs about 7.5 BMI units more, and this extra weight accounts for 70% of the total diabetes risk.

This means that being slim doesn’t exempt you from monitoring your blood sugar levels. For those carrying extra weight, lifestyle and weight management are essential parts of PCOS care.

PCOS is your body’s early warning system. How we respond can shape our health for the next twenty years!
Reference: Polycystic o***y syndrome and elevated body mass index independently increase type 2 diabetes risk with obesity-mediated risk dominating: a real-world data analysis of US patients. Fertility and Sterility, 2025. S0015-0282(25)01910-7. https://www.fertstert.org/article/S0015-0282(25)01910-7/fulltext
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Miscarriage Matters: The True Scale of Early Pregnancy LossDid you know that miscarriage affects 1 in 6 pregnancies, lea...
06/04/2026

Miscarriage Matters: The True Scale of Early Pregnancy Loss

Did you know that miscarriage affects 1 in 6 pregnancies, leading to a staggering 23 million losses every year? A landmark study by Quenby et al. published in The Lancet reveals the devastating psychological and health consequences of early pregnancy loss, which have long been underestimated.

It’s time we acknowledge the risk factors, economic costs, and clinical implications surrounding this issue. We must advocate for better data, specialist care, and compassionate support for women and families affected by pregnancy loss. Let’s come together to raise awareness and provide the understanding and resources that are so desperately needed.

Quenby S, Gallos ID, Dhillon-Smith RK, et al. Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss. The Lancet. 2021
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