Dr. Nora Willen

19/02/2025

What are warts?
Warts are common, benign, swollen buds on the skin caused by human papillomavirus (HPV). Warts are generally not dangerous, but they are contagious and spread through direct and indirect contact from person to person and even between different parts of your own body.
Different strains of HPV cause different types of warts. Here are some of the most common types of warts:
Common warts (verruca vulgaris)
- 5 til 10 mm
- Hard buds, rough, peeling texture with small black dots
- Often found on fingers, hands and feet, but can grow anywhere
Flat vortex (flat verruca)
- 1 mm, can grow in large groups
- Smooth, slightly swollen, brown or skin-colored pores
- Often found on the face, neck, arms and chest
Plantarvorter (myrmecia)
- Et par mm til et par cm
- Embedded under a thick layer of skin with small black dots in a suppressed center
- Often found on the feet, especially on the soles
- Can sometimes cause pain, especially when walking or standing (carrying weight)
Kønsvorter (condylomata acuminata)
- 1 to 5 mm, occurs in groups of 5 to 15 warts
- Skin colored, pink or red buds, can look like cauliflower
- Found in tissue around the ge***al area, but also in the mouth and throat

19/02/2025

Today the 16th January, when the air is moist and bitingly cold, many people experience that their skin conditions, including rashes, become more problematic. As a dermatologist specializing in skin conditions, I would like to shed light on the causes of rashes and why they can worsen at this time of the year.
Common causes of rashes
Rashes can develop for various reasons, often as a reaction to internal or external triggers. Some of the most common causes include:
Allergic reactions
Sensitivity to certain foods, medicines or environmental allergens such as dust mites or fungus can trigger skin inflammation.
Irritanter
Prolonged exposure to strong soaps, detergents, or other chemicals can remove the skin’s natural oils, leading to irritation and rashes.
Infektioner
Viral, bacterial, or fungal infections can result in characteristic rashes that can vary in appearance and severity depending on the underlying cause.
Underlying medical conditions
Conditions like eczema, psoriasis or rosacea can often flare up in response to environmental changes or stress.
Why rashes worsen in winter
Cold and dry air
The combination of low humidity and cold temperatures draws moisture out of the skin, making it dry and more susceptible to cracking, irritation and inflammation.
Centralvarme
Although central heating keeps us warm, it reduces indoor humidity, which exacerbates skin dryness and triggers worsening of conditions like eczema.
Layers on layers of clothes
Wearing multiple layers of wool or synthetic fabrics can trap sweat and irritate sensitive skin, leading to heat rash or worsening existing conditions.
Weakened skin barrier
The skin’s natural protective barrier is often compromised in winter, making it more vulnerable to irritants and allergens.

19/02/2025

Epidermolysis bullosa (EB) is a rare, inherited (genetic) skin disease that causes blisters and affects both men and women and all ethnic and racial groups. EB disrupts the proteins that connect the skin like Velcro, resulting in sores. There are several forms of EB, ranging from mild to severe. The main forms of EB are: EB Simplex, Junctional EB, and Dystrophic EB. Kindler syndrome is considered a "mixed" form of EB. Children with EB are called "Butterfly Children" because their skin is as fragile as the wings of a butterfly. Proteins and skin layers affected by the different types of EB: Patients with RDEB are born without normal type VII collagen. RDEB patients develop a persistent, scarring subtype of EB that produces painful blisters and sores on the skin and mucous membranes (e.g., mouth and throat). Dressing changes can take hours and must be done daily or every other day. The incidence of RDEB is estimated to be about 1 to 2 per 1,000,000 people. With improvements in nutrition, wound care, and management of complications, RDEB patients can live into their 30s or 40s and beyond.

19/02/2025

Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition Following 12-Week Oral Intake of a Supplement Containing Hydrolyzed Collagen
Background: Hydrolyzed collagen supplements are known to combat aging signs and enhance skin appearance. However, more clinical evidence is needed to substantiate their effectiveness.
Aim: This study evaluates the efficacy of a supplement containing hydrolyzed collagen and vitamin C (Absolute Collagen, AC) on biophysical parameters and visible aging signs for skin, scalp, and hair, taken either daily or every 48 hours.
Methods: Dermal collagen was measured using confocal microscopy and high-resolution ultrasound. Hydration, elasticity, wrinkles, and clinical trichoscopy were assessed, alongside expert visual grading. Efficacy was recorded at baseline, week 6, and week 12.
Results: After 12 weeks of daily AC supplementation:
- Collagen fragmentation decreased by 44.6% (p < 0.01).
- Skin hydration increased by 13.8% (p < 0.01).
- Skin elasticity improved by 22.7% (p < 0.01).
- Wrinkles decreased by 19.6% (p < 0.01).
- Scalp scaling improved by 11.0%, and hair count increased by 27.6% (p = n.s.). Clinical grading showed a 31.9% improvement in hair appearance (p < 0.01).
Conclusion: The AC supplement demonstrated clinical benefits for skin, scalp, and hair, whether taken daily or every 48 hours, over a 12-week period.
1. Introduction
Collagen is crucial for skin strength, stability, and resilience. As we age, collagen production declines due to intrinsic (genetics, hormonal changes) and extrinsic factors (UV radiation, pollution). This leads to visible signs of aging, including wrinkles and sagging.
Hydrolyzed collagen (HC) supplements are believed to combat these signs by stimulating collagen production. When ingested, HC is broken down into peptides, such as proline, hydroxyproline, and glycine, which can stimulate fibroblasts in the skin to produce more collagen.
Vitamin C plays a vital role in supporting collagen production by stabilizing the collagen triple-helix structure and cross-linking collagen fibers. It also acts as an antioxidant, neutralizing free radicals that damage the skin, particularly from UV exposure.
This study aims to provide authoritative evidence for the benefits of HC supplements on skin, scalp, and hair health, and assess their effects through advanced techniques like confocal microscopy and ultrasound imaging.
2. Methods
Study Design: A randomized, double-blind, placebo-controlled trial following Good Clinical Practice principles. Ethical approval was granted, and informed consent was obtained from participants.
Subjects: 140 participants (aged 40-60) with visible signs of aging were enrolled. The majority (90%) were female. Participants had a Glogau Wrinkle Score ≥2 and a hyperpigmentation score ≥4.
Test Products: The AC supplement contains 8000 mg of hydrolyzed marine collagen and 60 mg of vitamin C. The placebo matched the supplement in taste, texture, and appearance.
Measurement Conditions: Various skin measurements (hydration, elasticity, wrinkles) were performed at controlled temperatures and humidity, using specialized instruments like the Corneometer® and Cutometer®.
Key Measurement Tools:
- Confocal Microscopy: Used to visualize collagen structure, density, and fragmentation.
- Ultrasound: Measured collagen in the dermis and calculated the ratio of collagen in the upper vs. lower dermis.
- Skin Hydration and Elasticity: Measured using the Corneometer® and Cutometer® to assess moisture levels and skin firmness.
3. Results
The trial showed that the AC supplement significantly improved skin quality. Key findings include:
- Collagen Fragmentation: Decreased by 44.6% in the AC group compared to placebo (p < 0.01).
- Hydration: Increased by 13.8% (p < 0.01).
- Elasticity: Improved by 22.7% (p < 0.01).
- Wrinkles: Reduced by 19.6% (p < 0.01).
- Scalp and Hair Health: Scalp scaling improved by 11.0%, and hair count increased by 27.6% (although not statistically significant). Clinical grading showed a 31.9% improvement in hair appearance (p < 0.01).
4. Discussion
These results demonstrate the potential benefits of hydrolyzed collagen supplementation, with significant improvements in skin hydration, elasticity, collagen density, and the appearance of wrinkles. The positive effects on scalp health and hair count also highlight the broader potential of collagen for overall skin and hair health.
5. Conclusion
The study confirms that hydrolyzed collagen supplementation with vitamin C offers significant benefits for skin, scalp, and hair health. Daily use of the supplement resulted in enhanced collagen content, improved skin hydration and elasticity, and a reduction in the appearance of wrinkles. These findings support the use of collagen peptides in anti-aging treatments.

19/02/2025