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The ISEH - Institute of Sport, Exercise and Health

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The ISEH - Institute of Sport, Exercise and Health

Olympic health legacy, delivering excellence in research education & clinical services in sport & ex

Our vision is to be the leading institute for sports and exercise medicine in the world. The ISEH will provide excellence in elite sports performance and sports injury prevention and management whilst bridging the gap between elite sport, amateur sports and exercise prescription for the improvement of the healthcare of the whole population. The ISEH will:

Provide elite athlete treatment - a worldwide centre of excellence
*Deliver world class teaching, training and research in sport and exercise medicine

*Deliver health care needs of sport and exercise to elite and amateur levels

*Bridge the gap between the elite athlete and the weekend warrior through offering elite performance and training (including NHS patients)

*Translate our findings from research to gave an impact on the health of the nation.

19/11/2025

Take part in research: A small team of researchers at ISEH are recruiting volunteers to take part in a study exploring how exercise affects brain function.

Are you:
• Between 18 and 35 years old?
• Interested in exercise and research?

If so, the research team leading this would be very happy to hear from you.
The project’s purpose: Single bouts of exercise have been shown to support executive functioning – that is, the higher-order cognitive processes essential for everyday life, for up to an hour after exercise. However, the mechanisms driving this benefit remain unclear.

This project aims to investigate how different exercise modalities – including passive exercise, cycling, leg raises, and muscle stimulation, influence executive function in healthy adults. The data collected will contribute to ongoing research conducted by staff and students at UCL. This research is not intended for diagnostic purposes.

Study location: Institute of Sport, Exercise and Health (ISEH, 170 Tottenham Court Road, W1T 7HA).

Full details, including how to sign up can be found here: https://iseh.co.uk/news/latest-news/take-part-in-a-study-exploring-how-exercise-affects-brain-function

12/11/2025

ISEH’s Clinical Director, Professor Fares Haddad, and Consultant Radiologist, Justin Lee (also Honorary Associate Professor at UCL), were invited to attend the Emirates Sports Medicine Conference (ESMC) in Dubai earlier this month.

The event provided an excellent opportunity to showcase the innovative work being carried out at ISEH to a wide audience of sports medicine practitioners including those from across the Middle East. Their participation also highlighted the value of ISEH’s commitment to advancing education and best practice in sports and exercise medicine globally.

06/11/2025

Talk on AI and Health – Friday, 7 November (Online). Please join us this Friday, 12:00–13:00, for a talk by Prof. Finale Doshi-Velez on AI and Health. The session is organised by Uzair Hakim, and we’re delighted to invite ISEH’s audiences to attend virtually.

Speaker: Prof Finale Doshi-Velez Harvard University (Bio: https://finale.seas.harvard.edu/)

Title: Effective AI Decision Support in Health: Interpretability, Interaction, and Empowerment

Abstract: “The complexity of health-related settings provides both an opportunity for AI to support human decision-makers but also raises challenges. How can we vet whether a model trained on retrospective data is reasonable given all the potential confounders? When we present information to a user, how can we make sure that they rely on the information appropriately?

“I'll start this talk speaking to some of our work in interpretable reinforcement learning (applied to critical care settings), where we developed an approach that is not only statistically rigorous when it comes to drawing care insights from already-collected data, but is also easily inspectable by clinicians. I'll follow with work we have done to optimize the human+AI interaction itself - think of this as a mini reinforcement learning problem where we're trying to make sure that people use the AI without overrelying on it (some of this work in psychiatry settings). However, these approaches still force a certain structure of interaction on the human user. I'll conclude with a vision toward systems in which the human user can take an even more active role in determining what interventions will best improve their health.”

Join virtually: https://teams.microsoft.com/dl/launcher/launcher.html?url=%2F_%23%2Fl%2Fmeetup-join%2F19%3Ameeting_NjljMjhmNDctMjI5Mi00MTY0LTk2ZTYtNGU4OTZmYzIwYzI0%40thread.v2%2F0%3Fcontext%3D%257b%2522Tid%2522%253a%25221faf88fe-a998-4c5b-93c9-210a11d9a5c2%2522%252c%2522Oid%2522%253a%252260c9aa51-6240-455f-b497-1f1a245afc4b%2522%257d%26OR%3DWord%26CID%3DA6591699-6AD5-4026-A09D-3E752C8E2C72%26CT%3D1762430792449%26anon%3Dtrue&type=meetup-join&deeplinkId=561466b3-a5fe-4384-a7e7-f024acfbad7d&directDl=true&msLaunch=true&enableMobilePage=true&suppressPrompt=true

31/10/2025

We’re very pleased to share that technology used at the ISEH Concussion Clinic with Prof. Mike Loosemore MBE and David Bartlett, has been recognised at the 2025 Australia and New Zealand Sports Technology Awards (ANZSTA), winning in the Data Analytics category.

David Bartlett shared:

“Through the leadership and development support of Prof. Mike Loosemore, ScreenIT has enabled the Institute of Sport, Exercise and Health (ISEH) to become the heart of an integrated concussion care infrastructure in the UK, connecting athletes, clinicians and data in one seamless digital ecosystem that is setting a new global standard for concussion management.”

More here: https://iseh.co.uk/news/latest-news/tech-used-at-the-iseh-concussion-clinic-wins-award

30/10/2025

Findings examined: A new study led by ISEH’s Dr John Mitchell, with co-authors and close colleagues Dr Jo Blodgett and Prof. Mark Hamer, used data from more than 4,000 individuals to investigate how changes in 24-hour time use were associated with the risk of developing type II diabetes over a five-year period during midlife (ages 46 to 51).

What they did:
At age 46, participants wore accelerometers continuously for one week to capture time spent sleeping, sitting, and in light or moderate-to-vigorous physical activity (MVPA). Incident diabetes was assessed at age 51. The authors examined which behavioural shifts across the day were most favourable for diabetes prevention.

Findings:

Only increases in moderate-to-vigorous physical activity (MVPA), replacing time spent sitting, sleeping, or in light activity, were associated with a reduced risk of diabetes after adjusting for diet and body mass index (BMI).

The predicted effect of changing MVPA was asymmetric: losing 15 minutes of MVPA per day was associated with roughly a 25% higher diabetes risk, whereas an additional 30 minutes per day was required to achieve a similar reduction in risk.

Conclusion:
While light activity may reduce diabetes risk indirectly through lowering BMI, these findings indicate that beyond BMI, only increasing MVPA (at the expense of sitting, light activity, or sleep) was directly associated with lower diabetes risk.

Access the study published in Diabetes Research and Clinical Practice: https://www.sciencedirect.com/science/article/pii/S0168822725009714

23/10/2025

ISEH’s Dr Flaminia Ronca recently published research which focused on how different stages of the menstrual cycle and levels of activity affected women’s brain function. Together with Evelyn Watson, Isabel Metcalf and Dr Benjamin Tari, the study revealed that the menstrual cycle does influence cognitive performance, but not in the way women assume it does, and lifestyle matters more than phase…

Key points:
- There remains an incongruence between perception and performance: Women feel worst during menstruation, and they believe this is negatively impacting their cognitive performance, but there is no evidence to detriment in this phase.

- Reaction times were faster and fewer errors were committed on the day of ovulation: This was true for everyone, but particularly strong for elite athletes. Slower reaction times, but not fewer errors, occurred during the mid-luteal phase.

- Being physically active mattered more than cycle phase! While menstrual phase was associated with changes in cognition, sedentary participants were consistently slower, and made more errors, than more active participants, regardless of menstrual phase.

Conclusion: Our lifestyle, which is within our control, has a far greater effect on our brain than our menstrual phase.

Keep reading: https://www.theguardian.com/society/2025/oct/10/female-athletes-faster-reaction-times-day-ovulate-study

Access the paper published in Sports Medicine Open: https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-025-00924-8

22/10/2025

Drawing on our dedicated team’s experience of operating a midlife brain health clinic for retired elite contact sport athletes, (The Advanced BRAIN Health Clinic - ABHC at our facility), research led by Dr Neil Graham, with Dr Richard Sylvester, Prof. David Sharp Jessica Hain and Erin Rooney (co-authors and colleagues from the ABHC at ISEH plus other committed researchers), outlines a practical framework for assessing individuals with cognitive concerns.

This framework emphasises key clinical features, approaches to investigation, including neuroimaging and advanced fluid biomarkers. symptomatic management strategies, and emerging research directions.

Swipe for some key points from this research and for a comment from Dr Neil Graham, lead author.

Keep reading and access the framework:
https://iseh.co.uk/news/latest-news/retired-contact-sports-athletes-with-cognitive-concerns-a-practical-framework-for-assessing-individuals-with-cognitive-concerns-and-promoting-brain-health

21/10/2025

A new study led by Dr Neil Graham, (affiliated with ISEH through the Advanced BRAIN Health Clinic ABHC based at our facility) along with co-authors including Prof. Mathew Wilson, Jessica Hain, Erin Rooney, Dr Richard Sylvester and Prof. David Sharp from ABHC, found that former elite rugby players, especially those who played in forward positions, showed unique changes in their blood proteins linked to brain health.

The most consistent change was a decrease in a specific protein, which could one day help identify individuals at higher risk of brain problems early on.

This research was published in J Neurol Neurosurg Psychiatry(JNNP)

Swipe for key findings:

The authors found changes in blood biomarkers in former players that may affect how the brain handles amyloid beta. This could help track brain health in athletes who play contact sports – but more long-term research is needed to follow these changes over time.

The UK Advanced Brain Health Clinic (ABHC) study was created to find ways to protect brain health, reduce dementia risk, improve predictions and diagnose brain changes earlier.

Keep reading: https://iseh.co.uk/news/latest-news/study-reveals-unique-changes-in-blood-proteins-linked-to-brain-health-in-former-elite-rugby-players

Learn more about the ABHC study here: https://iseh.co.uk/clinical-services/clinics/advanced-brain-health-clinic-london

08/10/2025

Findings explained: A study led by ISEH’s Dr Theo Farley, a physiotherapist specialising in concussion, and co-authored by Prof. Mathew Wilson and Dr Richard Sylvester, along with a dedicated research team, examined how high-intensity exercise affects the body’s balance and eye movement systems (known as the vestibular and oculomotor systems) in both active and less active men and women.

These systems help to keep our balance, control our eye movements, and stabilise our vision when the head moves. Injuries to these systems can happen after head trauma, such as a concussion, and can lead to problems with balance, dizziness, and delayed recovery.

Some key points:
· 75 people took part: 45 university athletes and 30 sedentary students (those who didn’t meet the UK exercise guidelines of 150 minutes of moderate or 75 minutes of vigorous activity each week).
· Everyone first completed a baseline test using the Vestibular and Oculomotor Screening (VOMS) tool, which checks for symptoms like dizziness, headache, or blurred vision. Then, each person did a 5-minute treadmill run at a high effort level (17 out of 20 on the Borg scale). After running, they repeated the VOMS test three times, with 30 seconds between each test.
· The main measure was how many people experienced symptoms during the VOMS test.
· Doing high-intensity exercise can temporarily affect balance and eye movement control. This effect happens in both active and less active people, regardless of gender. And the results suggest that when the VOMS test is done (for example, before or after exercise) can make a difference, which is important for sports medicine and concussion testing.

Swipe for further details, and to keep reading, visit: https://iseh.co.uk/news/latest-news/how-high-intensity-exercise-influences-the-bodys-balance-and-eye-movement-systems

26/09/2025

In the UK, nearly two-thirds of adults are overweight or obese, and there are calls to eat less ultra-processed food (UPF), though there isn’t enough evidence yet to include UPFs in official dietary guidelines.

The Eatwell Guide gives advice on healthy eating, focusing on nutrients and food groups, but very few people follow it fully, and it doesn’t mention UPFs. Experts in the UK and US say more studies are needed, especially trials comparing UPFs with minimally processed foods (MPFs) while following healthy diet recommendations.

To study this, ISEH’s Professor Mark Hamer was a co-author of an randomised controlled trial, whereby a dedicated research team compared the effects of eating Minimally processed foods vs UPF diets for 8 weeks, looking mainly at weight changes and also at body composition, heart and metabolic health, and appetite.

We would like to thank the publications that have communicated the study’s findings – continue reading: https://www.nytimes.com/2025/08/04/well/eat/avoiding-ultraprocessed-foods-might-double-weight-loss.html

Access the paper: https://www.nature.com/articles/s41591-025-03842-0

24/09/2025

Over the last few days, we've been delighted to welcome a new cohort of masters students to the Sports Medicine, Exercise, and Health MSc programme. We were pleased to greet both in person and distance learners as they begin what promises to be a busy and rewarding year.

The programme is designed to give clinicians and practitioners a deeper understanding of sports medicine, sports injuries, and exercise medicine. It focuses on the evidence-based management of sports and musculoskeletal injuries, while also highlighting the crucial role of physical activity in preventing and treating chronic disease.

23/09/2025

The Institute of Sport, Exercise and Health (ISEH) and Meliora Medical (formerly Return2Play) have partnered to launch the Centre for Youth Sports Medicine - a pioneering centre dedicated to adolescent sports medicine.🏉🏐🏊‍♀️🚵🎾👟

ISEH, part of HCA Healthcare UK, is an internationally recognised centre of excellence in sports and exercise medicine (SEM). It delivers world-class care to elite adult and adolescent athletes, and active individuals, supported by cutting-edge research and education programmes that promote injury prevention, treatment, and long-term health through physical activity.

Meliora Medical provides expert general and sports medicine services to over 140 private schools across the UK, with a network of clinicians caring for more than 125,000 children. Their mission is to ensure that young people in schools, sports clubs, and universities receive the highest standards of care.

Together, ISEH and Meliora Medical have created the Centre for Youth Sports Medicine to deliver exemplary holistic care for adolescent athletes, while driving innovation through collaborative research and education. Core service lines will include: Sports Medicine, Orthopaedics, Cardiology, Respiratory Medicine, Gynaecology, Nutrition, and Psychology.

Full statement: https://iseh.co.uk/news/latest-news/centre-for-youth-sports-medicine-launched-with-meliora-medical

Address

170 Tottenham Court Road
London
W1T7HA

Opening Hours

Monday	8am - 8pm
Tuesday	8am - 8pm
Wednesday	8am - 8pm
Thursday	8am - 8pm
Friday	8am - 8pm
Saturday	8am - 8pm

Website

https://www.iseh.co.uk/

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