02/03/2026
Many people struggle with fatigue, anxiety, poor stress tolerance, or hormone imbalance - without understanding why.
One important piece of the puzzle may lie within your methylation pathways, particularly the COMT gene.
COMT (Catechol-O-Methyltransferase) plays a key role in breaking down neurotransmitters such as dopamine, adrenaline, and noradrenaline, as well as certain oestrogen metabolites.
Genetic variations in COMT can influence:
• how your body responds to stress
• mental focus and recovery
• sensitivity to caffeine or stimulants
• hormone metabolism
• nervous system regulation
This doesn’t mean genes determine your health outcomes - but they can help explain why individuals respond differently to stress, lifestyle changes, or supplements.
At My Body Fabulous Clinic, methylation testing allows us to assess genetic variants involved in detoxification, neurotransmitter balance, and hormone processing - helping us create truly personalised health strategies.
Understanding your biology allows us to move beyond guesswork and towards targeted care.
✨ Knowledge is the first step toward optimisation.