30/03/2026
What is Meso-Wharton?
Meso-Wharton P199® is a next-generation injectable biorevitalisation treatment developed by ABG Lab, designed to restore skin at a cellular level, not just superficially hydrate or fill.
It is particularly targeted for ageing, depleted skin (typically 40+), where stem cell activity and regenerative capacity have declined. 
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Key Science (what makes it different)
At its core is a synthetic Wharton’s Jelly Peptide (P199) — an analogue of embryonic signalling peptides.
• Acts as a “signal molecule” for skin stem cells
• Stimulates fibroblast activity → collagen + elastin synthesis
• Promotes cell turnover and dermal regeneration
• Enhances extracellular matrix repair 
👉 In simple terms:
This is not just hydration (like HA boosters) — it’s regenerative signalling.
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Composition
Typical formulation includes:
• Non-crosslinked Hyaluronic Acid → hydration + plumping
• Wharton’s Jelly Peptide P199 → stem cell stimulation
• Amino acids & nucleotides → cellular repair
• Vitamins & microelements → metabolic support
• Coenzymes / growth-factor-like signalling components 
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Mechanism of Action
Meso-Wharton works through 3 parallel pathways:
1. Stem cell activation
→ Reactivates dormant dermal stem cells
2. Fibroblast stimulation
→ Increased collagen, elastin, HA synthesis
3. Dermal restructuring
→ Improved density, elasticity, and skin quality
This leads to true dermal regeneration rather than temporary correction.
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Indications
• Skin ageing (loss of density, elasticity)
• Fine lines and deeper wrinkles
• Dull, thin, “tired” skin
• Neck + décolleté ageing
• Periorbital ageing (off-label in experienced hands)
• Post-procedure recovery (laser, RF, peels)
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Clinical Benefits
• Improved skin thickness & firmness
• Reduction in fine lines and wrinkles
• Enhanced hydration and glow
• Better skin resilience to environmental stress
• Subtle lifting and contour improvement 
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Treatment Protocol
• Typically 4–6 sessions
• Spaced 7–14 days apart
• Maintenance: every 6–12 months